Recent Advances of Novel Pharmaceutical Designs for Anti-cancer Therapies, 3rd Edition
A special issue of International Journal of Molecular Sciences (ISSN 1422-0067). This special issue belongs to the section "Molecular Pharmacology".
Deadline for manuscript submissions: 15 October 2024 | Viewed by 28
Special Issue Editor
Interests: medicinal chemistry; natural products; multi-component reactions; metal-based drugs; antibiotics and antimycotics; anticancer drugs; antiparasitic drugs; antiviral drugs
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
The development of efficient and well-tolerated anticancer drugs is one of the main healthcare challenges of the century, with rising numbers of cancer patients worldwide. The close correspondence of clinicians, tumor biologists and medicinal chemists is mandatory for the successful establishment of new cancer treatments. Small-molecule protein binders and enzyme inhibitors, natural products, DNA-targeting alkylating agents and metal complexes form the main part of the current arsenal of anticancer drugs, which can serve as starting points for the development of new compounds with improved activity, bioavailability and potential to overcome drug resistance. Repurposed drugs and cost-effective new compounds obtained from multi-component reactions or few-step syntheses can become broadly available anticancer drugs. Computer-aided drug design contributes to the optimisation of existing drugs, as well as the identification of the first-generation inhibitors of new cancer targets. Sophisticated formulation systems improve pharmacokinetics and the tumor targeting properties of anticancer drugs. Recent drug research efforts aim at cancer epigenetics, cancer stem-like cells, tumor microenvironment and immunology. This Special Issue intends to showcase the current efforts on anticancer drug design and development. Original research articles, review articles, and short communications within (but not restricted to) the described research fields are welcome.
Dr. Bernhard Biersack
Guest Editor
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. International Journal of Molecular Sciences is an international peer-reviewed open access semimonthly journal published by MDPI.
Please visit the Instructions for Authors page before submitting a manuscript. There is an Article Processing Charge (APC) for publication in this open access journal. For details about the APC please see here. Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
Keywords
- cancer
- anticancer drugs
- drug design
- targeted therapy
- immunotherapy
- molecular target
- molecular mechanism
- drug resistance
