Molecular Mechanisms of Periodontal Disease and Autoimmune Diseases
A special issue of International Journal of Molecular Sciences (ISSN 1422-0067). This special issue belongs to the section "Molecular Immunology".
Deadline for manuscript submissions: closed (28 February 2024) | Viewed by 285
Special Issue Editor
Interests: periodontitis; gingivitis; inflammation; antibodies; cytokines; immune response; antigens; bacteria
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
Periodontitis is the sixth most common health condition in the world, affecting at least 47% of adults aged 30 years and older in the United States. Periodontitis is a destructive inflammatory disease triggered by dental bacterial plaque that if left untreated can lead to tooth mobility and tooth loss. Several studies have demonstrated the involvement of autoimmune responses in periodontal disease, but also that periodontal diseases can increase the susceptibility or exacerbate autoimmune diseases such as rheumatoid arthritis, type I diabetes mellitus, systemic lupus erythematosus, Crohn's disease, scleroderma and Sjögren's syndrome. Understanding the linking mechanisms of pathogenesis characterized by a dysregulated host immune response in periodontal and autoimmune diseases may provide new therapeutic options and targets for both disorders.
The aim of this Special Issue is to provide the most updated research on the molecular mechanisms that underlie the two-way connection between periodontal disease and autoimmune diseases. Both original research and review articles on this topic will be accepted.
Dr. Evangelos Papathanasiou
Guest Editor
Manuscript Submission Information
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Keywords
- periodontitis
- gingivitis
- inflammation
- antibodies
- cytokines
- immune response
- antigens
- bacteria
