New Insights into Viral Vector Mediated Gene Therapy
A special issue of International Journal of Molecular Sciences (ISSN 1422-0067). This special issue belongs to the section "Molecular Microbiology".
Deadline for manuscript submissions: 30 August 2024 | Viewed by 151
Special Issue Editor
Special Issue Information
Dear Colleagues,
In the past decade, viral vector-mediated gene therapy has shown their potential for the treatment of inherited disorders. With 26 gene therapy products approved worldwide, including genetically modified cell therapies, viral vectors are now used for the treatment of retinal, metabolic or neurodegenerative diseases, as well as cancer. While oncolytic, lentiviral, adenoviral or adeno-associated viral vectors have their own advantages, some limitations related to production capacity, tissue targeting, vector integration, immunogenicity or toxicity remain challenging.
This Special Issue of IJMS invites submissions of original research or review articles addressing recent developments in viral vectors for gene therapy, including vector design and production, vector–cell interactions, and proof-of-concept in preclinical models, as well as innovative strategies to prevent vector-mediated toxicity.
Dr. Gwladys Gernoux
Guest Editor
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. International Journal of Molecular Sciences is an international peer-reviewed open access semimonthly journal published by MDPI.
Please visit the Instructions for Authors page before submitting a manuscript. There is an Article Processing Charge (APC) for publication in this open access journal. For details about the APC please see here. Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
Keywords
- viral vector
- gene therapy
- gene delivery
- adenovirus
- adeno-associated virus
- lentivirus
- analytics
- preclinical testing
- inherited disorders
