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Mesenchymal Stromal and Immune Cells’ Involvement in Human Diseases and Their Treatment

A special issue of International Journal of Molecular Sciences (ISSN 1422-0067). This special issue belongs to the section "Molecular Immunology".

Deadline for manuscript submissions: 30 October 2024 | Viewed by 222

Special Issue Editor


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Guest Editor
The Keenan Research Centre for Biomedical Science of St. Michael’s Hospital, Unity Health Toronto, University of Toronto, Toronto, ON M5B 1T8, Canada
Interests: stem cells (and MSCs, in particular); mitochondria; macrophages; brain and lung injury; sepsis; ischemia-reperfusion; TGFβ pathways; translational research and clinical studies
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Special Issue Information

Dear Colleagues,

We are pleased to announce this thematic Special Issue on “Mesenchymal Stromal and Immune Cells’ Involvement in Human Diseases and Their Treatment”. MSCs are multipotent cells that have demonstrated promise in various preclinical disease models, including lung injury, sepsis, pneumonia, and cardiovascular diseases. MSCs are also being tested in clinical trials in critically ill patients with sepsis, in prevention of graft vs. host disease, acute lung injury, COVID-19 pneumonia, liver cirrhosis, cancer, wound healing problems, etc. Despite extensive research in the MSC field, however, our understanding of the mechanisms of their action is incomplete, and this Special Issue will advance our knowledge in this important research field.

The main scope of the issue is to highlight the current state of knowledge of molecular mechanisms by which MSCs act in health and disease, exhibit potent paracrine properties, modulate host immune responses and inflammation, interact with the environment, and orchestrate tissue repair, at both the local and systemic levels.

We welcome original research and up-to-date review papers. Generally, pure clinical research or model studies, survey studies, and correlation research are out of the scope of IJMS. However, clinical or model submissions with biomolecular experiments are welcomed.

Dr. Mirjana Jerkić
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. International Journal of Molecular Sciences is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. There is an Article Processing Charge (APC) for publication in this open access journal. For details about the APC please see here. Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • MSC homing
  • macrophages
  • lung injury
  • inflammation
  • sepsis
  • COVID-19
  • heart
  • liver
  • cell therapy

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Published Papers

This special issue is now open for submission.
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