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Thyroid Dysfunctions: Molecular Mechanisms Underlying Clinical Consequences

A special issue of International Journal of Molecular Sciences (ISSN 1422-0067). This special issue belongs to the section "Molecular Endocrinology and Metabolism".

Deadline for manuscript submissions: 30 July 2024 | Viewed by 139

Special Issue Editor

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Guest Editor
SOC Endocrinology, ASU FC—Oncology Area Department, University-Hospital S. Maria della Misericordia, 33100 Udine, Italy
Interests: thyroid cancer; thyroid eye disease; thyroid; hormones; adrenal; adrenal disease; medullary thyroid cancer; multiple endocrine neoplasia; aldosterone; licorice
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Special Issue Information

Dear Colleagues,

Thyroid hormones play a fundamental role in the homeostasis of all organs and tissues. Therefore, thyroid dysfunction, both as an excess and defect of thyroid hormones, has a considerable impact on human health, particularly on the heart, bone tissue, skin, central and peripheral nervous systems, kidney, and adipose tissue; however, the diagnosis of thyroid dysfunction is not always easy and misdiagnoses can often occur due to interference with laboratory assay methods. Moreover, not all of the molecular mechanisms by which the excess or defect of thyroid hormones cause alterations to target organs are well known.

In this Special Issue, original studies on all aspects of the molecular mechanisms by which thyroid disorders lead to clinical implications are welcome, such as thyroid-induced osteoporosis, thyroid eye disease, thyroid cardiac alterations, thyroid cancer, or thyroid genetic disorder. It will also cover reports providing new insights into possible laboratory interference in thyroid hormone assays leading to clinical consequences.

Dr. Jacopo Manso
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. International Journal of Molecular Sciences is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. There is an Article Processing Charge (APC) for publication in this open access journal. For details about the APC please see here. Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.


  • thyroid
  • thyroid dysfunctions
  • thyroid hormones
  • thyroid disorders
  • molecular mechanisms

Published Papers

This special issue is now open for submission.
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