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Signaling Molecules Involved in Gametes Development, Differentiation and Fertilization 2.0

A special issue of International Journal of Molecular Sciences (ISSN 1422-0067). This special issue belongs to the section "Molecular Biology".

Deadline for manuscript submissions: 26 August 2024 | Viewed by 123

Special Issue Editors


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Guest Editor
Dipartimento di Medicina Sperimentale, Sez. Fisiologia Umana e Funzioni Biologiche Integrate, Università degli Studi della Campania ‘Luigi Vanvitelli’, Via Santa Maria di Costantinopoli, 16-80138 Napoli, Italy
Interests: reproduction; spermatogenesis; reproductive toxicology; apoptosis; testicular cytoskeleton; gene expression; fertility
Special Issues, Collections and Topics in MDPI journals

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Guest Editor
Dipartimento di Medicina Sperimentale, Sez. Fisiologia Umana e Funzioni Biologiche Integrate, Università degli Studi della Campania ‘Luigi Vanvitelli’, Via Santa Maria di Costantinopoli, 16-80138 Napoli, Italy
Interests: reproduction; spermatogenesis; reproductive toxicology; apoptosis; testicular cytoskeleton; blood-testis barrier; fertility
Special Issues, Collections and Topics in MDPI journals

Special Issue Information

Dear Colleagues,

The reproductive activity of a species is crucial to ensure its survival and genetic variability. Therefore, the production and differentiation of good-quality gametes, which are capable of fertilizing or being fertilized, are of primary importance. In contrast, there is a worrying decline in fertility worldwide, directly proportional to the increasing worsening of the quality of gametes. Thus, studies on the molecular mechanisms that regulate male and female gametogenesis are encouraged, not only to add new knowledge on the biological aspects of these differentiative processes but also to identify new potential markers of proper fertility and/or therapeutic targets on which to act to improve it.

This Special Issue aims to cover the physiological and pathological aspects of gamete production and differentiation at histological, cellular, and biomolecular levels. These include, but are not limited to, all aspects related to gamete function, including sperm and oocyte maturation, epididymal transit, fertilization, sperm motility, capacitation, and acrosome reaction. Papers focusing on the influence of environmental pollutants (endocrine-disrupting chemicals, microplastics, etc.), as well as metabolic disorders (overweight/obesity, diabetes), on gametes are also welcome to be submitted. Papers focusing on any vertebrate (including human) and non-vertebrate species will be accepted, as well as in vitro and ex vivo studies. This Special Issue welcomes research articles, case reports, short communications, letters, and review articles.

Prof. Dr. Sergio Minucci
Dr. Massimo Venditti
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. International Journal of Molecular Sciences is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. There is an Article Processing Charge (APC) for publication in this open access journal. For details about the APC please see here. Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • spermatogenesis
  • oogenesis
  • spermatozoa
  • oocyte
  • fertilization
  • acrosome reaction
  • fertility
  • epidydimal transit
  • endocrine disrupting chemicals
  • testicular and ovarian cancer

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This special issue is now open for submission.
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