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Cell Metabolism: Its Physiology, Dysfunction, and Related Metabolic Complications

A special issue of International Journal of Molecular Sciences (ISSN 1422-0067). This special issue belongs to the section "Molecular Biology".

Deadline for manuscript submissions: 20 June 2024 | Viewed by 404

Special Issue Editor


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Guest Editor
Department of Biological Sciences, Ulsan National Institute of Science and Technology, Ulsan 44919, Republic of Korea
Interests: DNA methylation; TET proteins; hematopoietic stem cells; hematopoiesis; leukemia; cancer epigenetics; cancer therapy; drug screen; metabolic diseases; obesity; diabetes; biosensor; signaling and gene expression
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Special Issue Information

Dear Colleagues,

Metabolism, the cornerstone of life, is finely orchestrated by the complex interplay among cells within specialized tissues, notably adipocytes, muscle cells, and hepatocytes. Adipocytes govern systemic energy and glucose homeostasis, thermogenesis, and hormone secretion. Muscle cells, with their high energy demands, also play a central role in glucose uptake and utilization. Dysfunction within these cells disrupts the metabolic balance, contributing to various complications, including insulin resistance, obesity, diabetes, and cardiovascular diseases. Additionally, hepatocytes, the metabolic powerhouses, also dictate glucose and lipid metabolism and detoxification, and they are the central players in diabetes, fatty liver disease, hepatic inflammation and fibrosis, and liver cancers. This Special Issue aims to explore the intricate molecular events and mechanisms that underlie both normal and aberrant cellular metabolism, along with the associated metabolic disorders.

We invite submissions of original research articles, reviews, and clinical studies that address, but are not limited to, the following areas:

  • Molecular insights into adipocyte differentiation and function;
  • Adipose tissue inflammation and metabolic dysfunction;
  • Role of adipokines in metabolism;
  • Adipose tissue remodeling in health and disease;
  • Hepatic glucose and lipid metabolism;
  • Crosstalk among liver, muscle, and adipose tissues in metabolic regulation;
  • Genetic and epigenetic regulation of metabolism;
  • Obesity and diabetes: mechanisms, complications, and therapeutic interventions;
  • Steatosis, hepatitis, and cirrhosis: underlying mechanisms and therapeutic targets;
  • Liver cancers: pathology and therapeutic strategies;
  • Innovative therapeutic approaches to treat metabolic diseases.

We look forward to receiving your contributions.

Dr. Myunggon Ko
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. International Journal of Molecular Sciences is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. There is an Article Processing Charge (APC) for publication in this open access journal. For details about the APC please see here. Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • cell metabolism
  • adipocytes
  • muscle cells
  • hepatocytes
  • insulin resistance
  • inflammation
  • obesity
  • diabetes
  • hepatic disorders
  • cardiovascular diseases
  • cancers

Published Papers

This special issue is now open for submission.
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