Special Issue "Chronic Kidney Disease"
A special issue of International Journal of Environmental Research and Public Health (ISSN 1660-4601). This special issue belongs to the section "Health Behavior, Chronic Disease and Health Promotion".
Deadline for manuscript submissions: closed (30 November 2019) | Viewed by 42150
Interests: epidemiology; public health; RCT; systematic reviews; CKD
2. Department of Clinical and Biological Sciences, ASOU San Luigi, University of Turin, 10124 Turin, Italy
Interests: CKD; dietary management and CKD; hemodialysis; tailored dialysis (daily dialysis, incremental dialysis); ethical aspects; long term outcomes; pregnancy and CKD; pregnancy and dietary management in kidney transplantation
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Chronic kidney disease (CKD) has been redefined in the new millennium as any alteration of kidney morphology, function, or blood or urine composition lasting for at least three months. This broad definition encompasses also diseases or conditions that are associated with normal kidney function, such as a kidney scar from an acute pyelonephritis episode or a single kidney resulting from kidney donation. The choice of broadening the definition acknowledges the fact that even the first stages of CKD are associated with adverse clinical events (for example, in pregnancy) and with an increased risk of morbidity and mortality.
CKD is a relevant public health problem: according to the 2015 Global Burden of Disease Study, it was the 12th cause of death, leading to 1.1 million deaths worldwide each year; moreover, overall CKD mortality has increased by 31.7% over the last 10 years. These data are likely to be underestimated, and indeed the world kidney day in 2019 is dedicated to care for all patients in all settings, a goal not yet accomplished in developing countries.
Establishing the prevalence of CKD is difficult, since the disease is not found unless searched for, in particular in the early phases of the disease; furthermore, the role of CKD as a cause of death is evident where renal replacement therapy (RRT) is not available, but its role in increasing death risk is not easily calculated. RRT consumes about 3–5% of the global healthcare budget where dialysis is available without restrictions; however, dialysis is not widely available in about two thirds of the overall world population.
While the prevalence of CKD is overall increasing with extending lifespan, being linked to diabetes, hypertension, obesity, and atherosclerosis, CKD is at least partly preventable, and its effects may be at least partly counterbalanced by early and appropriate care. Finally, the World Health Organisation stresses the fact that CKD treatment requires a systematic policy approach, to strengthen all relevant aspects of the health system.
We will welcome papers on all aspects of CKD, including organisation, cost, and models of care. Papers from developing countries will be particularly welcomed.
Prof. Elisabetta Versino
Prof. Giorgina Barbara Piccoli
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- kidney transplantation
- morbidity and costs of care–health services integration