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Horticulturae
Special Issues
Bioactive Compound Levels of Medicinal Plants
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Bioactive Compound Levels of Medicinal Plants

A special issue of Horticulturae (ISSN 2311-7524). This special issue belongs to the section "Medicinals, Herbs, and Specialty Crops".

Deadline for manuscript submissions: closed (31 March 2022) | Viewed by 9932

Special Issue Editor

Dr. Bimal Kumar Ghimire

E-Mail Website
Guest Editor
Department of Crop Science, College of Sanghuh Life Science, Konkuk University, Seoul 05029, Korea
Interests: plant biotechnology; phytoconstituents aromatic and non-aromatic medicinal plants such as phenolic compounds and essential volatile compounds; genetic transformation; plant regeneration; bioreactor culture; biofuels and bioenergy research; genetic diversity in medicinal plants, crops, and bioenergy plants; biological activities, including antioxidant and antidiabetic; neuroprotective activity of plants
Special Issues, Collections and Topics in MDPI journals

Special Issue Information

Dear Colleagues,

Plants synthesize various bioactive compounds, including phenolic, flavonoids, caffeine, and carotenoids, many of which are important drug ingredients. Additionally, plant-based foods are significant sources of vitamins, minerals, and bioactive compounds on which human metabolism is also dependent.

Recently, studies on bioactive compounds in plants have attracted attention globally due to those compounds’ role in curing cardiovascular and other human diseases, stimulating the immune system, and delaying the aging process, as well as in anticancer action, atherosclerosis, and mitigation of Alzheimer’s disease, to name a few. Several studies have shown that the disease preventive potentialities of dietary food have been associated with the constituent polyphenols present in plants. Thus, research on plant-based bioactive compounds has grown due to their association with a number of biological activities. Moreover, these compounds play different functions in plants themselves, including in pollination systems, UV light protection, protection against pathogens and diseases, and plant adaptation to different growth conditions.

Plant secondary metabolites have an enormous added value because they are used to treat diseases, as well as in the fields of food, cosmetics, and agrochemicals. The application of synthetic drugs and antioxidant and antimicrobial agents sadly comes with some serious health concerns, and as such, there has recently been increased interest in finding the active ingredients in plants that can act as natural antioxidant and anti-infective agents that can replace synthetic compounds and contribute to human health and food preservation.

Recognizing the growing interest in this area, the present Special Issue aims to serve as a comprehensive collection of recent research achievements in the bioactive compounds of important medicinal plants and their applications. The scope of this project also includes research works using in vitro and in vivo experiments to identify health benefits and potential applications, as well as alternatives in the prevention or treatment of disease.

Dr. Bimal Kumar Ghimire
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Horticulturae is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2200 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • plant metabolites
  • bioactivity
  • biotechnology
  • biomedicine
  • natural products
  • nutraceuticals

Published Papers (4 papers)

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Research

11 pages, 569 KiB  
Article
Optimization of Cultivation Type and Temperature for the Production of Balloon Flower (Platycodongrandiflorum A. DC) Sprouts in a Plant Factory with Artificial Lighting
by Thi Kim Loan Nguyen, Jin-Hui Lee, Ga Oun Lee, Kye Man Cho, Du Yong Cho and Ki-Ho Son
Horticulturae 2022, 8(4), 315; https://doi.org/10.3390/horticulturae8040315 - 8 Apr 2022
Cited by 1 | Viewed by 2033
Abstract
The objective of this study was to determine the efficiency of balloon flower sprout’s saponin production in a plant factory with artificial lighting (PFAL). Balloon flower has been traditionally used as herbal medicine and now, it is used as a medicinal plant as [...] Read more.
The objective of this study was to determine the efficiency of balloon flower sprout’s saponin production in a plant factory with artificial lighting (PFAL). Balloon flower has been traditionally used as herbal medicine and now, it is used as a medicinal plant as well as a functional food. It is important to establish the cultivation conditions for the stable production of high-quality balloon flower. Therefore, this study aimed to investigate the effects of culture systems and temperature conditions on the growth and saponin accumulation of balloon flower sprouts in controlled environment systems. One-year balloon flower roots were cultivated in soil and soilless culture systems at different temperature conditions (20, 25, and 30 °C) for 17 days. The results showed that the shoot fresh weight and shoot dry weight of the balloon flower sprouts grown in the soilless culture system at 25 °C were significantly increased by about 1.29 and 1.58 times, respectively, as compared with those of the sprouts grown in a soil culture system. Sprouts grown in the soilless culture system at 25 °C also recorded the highest root fresh weight, whereas there was no significant difference in root dry weight among the treatments. The plant height results showed an increased trend similar to that of the shoot fresh weight and shoot dry weight of the balloon flower sprouts. The concentrations of platycodin D3 (Pd-D3), polygalcin D (Pc-D), and total saponin in the shoot parts were highest in the soilless culture system at 20 and 25 °C. The root parts of sprouts grown in the soilless culture system at 30 °C also had higher deapioplatycodin D (Dpd-D) and total saponin concentrations. Overall, these results suggest that a soilless culture system with temperature conditions at 20 and 25 °C is suitable for improving the growth and saponin concentration of balloon flower cultivated in PFALs. Ultimately, our research should be a valuable resource for future research on the production of medicinal plants such as sprouts and should provide basic information to establish methods for enhancing the growth and bioactive compounds in balloon flower. Full article
(This article belongs to the Special Issue Bioactive Compound Levels of Medicinal Plants)
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13 pages, 1667 KiB  
Article
Elicitation of Medicinal Plants In Vivo—Is It a Realistic Tool? The Effect of Methyl Jasmonate and Salicylic Acid on Lamiaceae Species
by Wafae Kandoudi, Péter Radácsi, Beáta Gosztola and Éva Zámboriné Németh
Horticulturae 2022, 8(1), 5; https://doi.org/10.3390/horticulturae8010005 - 22 Dec 2021
Cited by 16 | Viewed by 3275
Abstract
Salicylic acid (SA) and methyl jasmonate (MeJa) are prominent phytohormones that are involved in stress reactions. Both compounds may influence the biosynthesis of secondary compounds; however, scientific experiments in vivo are rare and contradictive. This paper reports on a study on the elicitation [...] Read more.
Salicylic acid (SA) and methyl jasmonate (MeJa) are prominent phytohormones that are involved in stress reactions. Both compounds may influence the biosynthesis of secondary compounds; however, scientific experiments in vivo are rare and contradictive. This paper reports on a study on the elicitation of volatiles and total phenolics (TPC) by MeJa and SA. The subjects were four Lamiaceae species studied in open field conditions in Budapest (Hungary). According to the results, both elicitors provoked specific responses in each plant species depending on the dosage applied and the parameter studied; 2 mM of SA stimulated essential oil (EO) accumulation in marjoram and peppermint, while in hyssop 0.1 mM was optimal. MeJa proved to be effective only in marjoram and in basil. In marjoram, cis-sabinene hydrate was decreased and in hyssop, isopinocamphone was increased by both dosages of SA. In peppermint, pulegone content was reduced by 2 mM SA, but no significant change of the major components of basil EO was detected. SA was successful in increasing TPC and antioxidant activity (AC) in three of the experimental species, but not in hyssop. In marjoram, only 0.1 mM induced TPC and eventually AC, while in peppermint and basil both dosages of SA were effective. Optimalisation of the treatments is suggested in further in vivo experiments. Full article
(This article belongs to the Special Issue Bioactive Compound Levels of Medicinal Plants)
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23 pages, 4398 KiB  
Article
Effects on Growth and Metabolism of Difference between Day and Night Temperatures (DIF) and Supplementation with Rare Earth Elements (REE) in Micropropagated Dendrobium aphyllum (Roxb.) C. E. Fischer
by Boling Liu, Lijun Tang, Bowen Gao, Byoung Ryong Jeong, Shijun Deng and Hao Wei
Horticulturae 2021, 7(11), 425; https://doi.org/10.3390/horticulturae7110425 - 21 Oct 2021
Viewed by 1637
Abstract
Dendrobium aphyllum (Roxb.) C. E. Fischer is an ornamental plant with certain medicinal values from the Orchidaceae family. Currently, micropropagation is the main means through which it is propagated. In this research, the effects of different daytime and nighttime temperatures (DIF) and medium [...] Read more.
Dendrobium aphyllum (Roxb.) C. E. Fischer is an ornamental plant with certain medicinal values from the Orchidaceae family. Currently, micropropagation is the main means through which it is propagated. In this research, the effects of different daytime and nighttime temperatures (DIF) and medium supplementation with rare earth elements (REE) on the growth and metabolism of D. aphyllum during a micropropagation period were investigated. Three kinds of REE nitrates, La(NO₃)₃, Ce(NO₃)₃ and Nd(NO₃)₃, at four concentrations, 50, 100, 150, and 200 μM, were added to the culture medium. Three DIFs, 0, 6 and 12 °C, with an identical mean daily temperature of 20 °C, were used with photoperiod/dark period temperatures of 20/20 °C, 23/17 °C and 26/14 °C, respectively. After four weeks of culture, both supplemental REE and DIF treatments promoted growth of the plant compared with the control group. With increased REE concentration and DIF, the growth of the plants was suppressed and symptoms of stress response occurred. At the same concentration, Ce(NO₃)₃ had a more significant promotional effect on plant growth. In general, the medium supplemented with 100 μM Ce(NO₃)₃ combined with a 6 °C DIF was the most optimal for the vegetative growth of the plant. A 12 °C DIF promoted synthesis of more primary metabolites such as total proteins and polysaccharides. From the perspective of improving the medicinal values of this plant, increasing the DIF for an optimal growth environment is a valuable reference. This study can provide a technical basis for the propagation and production of Dendrobium aphyllum in the future. Full article
(This article belongs to the Special Issue Bioactive Compound Levels of Medicinal Plants)
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15 pages, 1077 KiB  
Article
Nutraceutical and Functional Properties of Peel, Pulp, and Seed Extracts of Six ‘Köhnü’ Grape Clones
by Muhammed Kupe, Neva Karatas, Mehmet Settar Unal, Sezai Ercisli, Mojmir Baron and Jiri Sochor
Horticulturae 2021, 7(10), 346; https://doi.org/10.3390/horticulturae7100346 - 29 Sep 2021
Cited by 6 | Viewed by 2104
Abstract
Grape production has a long history in the Elazig province and surrounding vicinity and produced grapes have been used for table consumption and also processed into traditional beverages, Şıra (special non-alcoholic grape juice) and wine. In the Elazig province, the main grape cultivars [...] Read more.
Grape production has a long history in the Elazig province and surrounding vicinity and produced grapes have been used for table consumption and also processed into traditional beverages, Şıra (special non-alcoholic grape juice) and wine. In the Elazig province, the main grape cultivars are ‘Ağın Beyazı’, ‘Öküzgözü’, ‘Boğazkere’, ‘Şilfoni’, ‘Tahannebi’, and ‘Köhnü’. Among them, ‘Köhnü’ cultivar is highly preferred by consumers due to its black color and perfect berry characteristics. The cultivar has grown for centuries in different parts of Elazig and shows a great variability for most of its morphological and biochemical characteristics. In the present study, we aimed to determine morphological and biochemical traits in six ‘Köhnü’ clones sampled from Elazığ. The cluster weight of six clones was found between 334–394 g. The highest total phenolic content was observed in seeds followed by peel and pulp samples. The seed extract of Clone 2 had the highest total phenolic content at 254 mg gallic acid equivalent/100 g fresh weight. The results also showed that peel, pulp, and seed samples of ‘Köhnü’ grape clones had considerable amounts of antioxidant components determined by DPPH (1,1-Diphenyl-2-picryl-hydrazyl), FRAP (ferric reducing antioxidant power), and TEAC assays and might be rich sources of natural antioxidants. Among the six ‘Köhnü’ clones, Clone 3, and Clone 6 differed from the others in respect to the highest cluster weight, the highest concentrations of total phenolic content, and antioxidant activity. The results also implied that all clones could be used potentially as a readily accessible source of natural antioxidants and as a possible pharmaceutical supplement. Full article
(This article belongs to the Special Issue Bioactive Compound Levels of Medicinal Plants)
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