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Medication Adherence and Beliefs About Medication: Second Edition
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Medication Adherence and Beliefs About Medication: Second Edition

A special issue of Healthcare (ISSN 2227-9032). This special issue belongs to the section "Medication Management".

Deadline for manuscript submissions: closed (1 October 2022) | Viewed by 14955

Special Issue Editors

Dr. Sara Garfield

E-Mail Website
Guest Editor
Imperial College Healthcare NHS Trust, UCL School of Pharmacy, London, UK
Interests: patients' perceptions of medication; factors influencing patients' decisions about treatment; shared decision making; medication adherence; safety and quality of medication use
Special Issues, Collections and Topics in MDPI journals
Dr. Gaby Judah

E-Mail Website
Guest Editor
NIHR North West London Patient Safety Research Collaboration (PSRC), Institute of Global Health Innovation (IGHI), Imperial College London, London, UK
Interests: behaviour change; predictors of health-related behaviours; cancer screening; medication adherence; improving patient safety
Special Issues, Collections and Topics in MDPI journals

Special Issue Information

Dear Colleagues,

The scope of this Special Issue is to disseminate research evidence on patients’ and carers’ beliefs about and experiences of medicines, including barriers and facilitators to taking medication, and how these might impact medication adherence. The Issue will include research on the development and testing of interventions to increase adherence, particularly when these are grounded in the patient/carer perspective. Research relating to shared decision making about medicines between patients and healthcare professionals is within the scope of the issue. 

Submissions may be quantitative, qualitative, or mixed-methods research or reviews that meet established review standards, and data may be from primary or secondary sources. All types of study design will be considered. All healthcare settings, including acute care, long-term care, community and home care, mental health, and primary care will be included. All populations and medical conditions will be considered. 

Dr. Sara Garfield
Dr. Gaby Judah
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Healthcare is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2700 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • adherence
  • medicines
  • shared decision making
  • patients
  • carers
  • beliefs
  • attitudes
  • barriers
  • facilitators

Published Papers (7 papers)

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Research

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12 pages, 1324 KiB  
Article
Persistence to Medications for Benign Prostatic Hyperplasia/Benign Prostatic Obstruction-Associated Lower Urinary Tract Symptoms in the ASL TO4 Regione Piemonte (Italy)
by Lucrezia Greta Armando, Raffaella Baroetto Parisi, Elisa Remani, Mariangela Esiliato, Cristina Rolando, Valeria Vinciguerra, Abdoulaye Diarassouba, Clara Cena and Gianluca Miglio
Healthcare 2022, 10(12), 2567; https://doi.org/10.3390/healthcare10122567 - 17 Dec 2022
Cited by 2 | Viewed by 1454
Abstract
Background: Pharmacological treatment of benign prostatic hyperplasia (BPH)/benign prostatic obstruction (BPO)-associated lower urinary tract symptoms (LUTS) aims at improving patients’ quality of life by managing urinary symptoms and preventing complications and disease progression. However, continuous use of drugs to treat BPH/BPO-associated LUTS decreases [...] Read more.
Background: Pharmacological treatment of benign prostatic hyperplasia (BPH)/benign prostatic obstruction (BPO)-associated lower urinary tract symptoms (LUTS) aims at improving patients’ quality of life by managing urinary symptoms and preventing complications and disease progression. However, continuous use of drugs to treat BPH/BPO-associated LUTS decreases over time. The aim of this retrospective observational study was to describe use of α1-adrenoceptor antagonists (ABs) and steroid 5α-reductase inhibitors (5ARIs) by adult (age ≥ 40 years) men in the ASL TO4, a Local Health Authority in the northern area of the city of Turin (Italy). Methods: Persistence measures were adopted as a robust, informative, and feasible way to understand medication-taking behavior and to assess patient compliance. Results: A total of 4309 men (median age 71 years) were enrolled. Monotherapy was the treatment option prescribed to the largest part of the study population. However, ≥two drugs were prescribed to a substantial proportion of men (23%). Men prescribed alfuzosin or dutasteride had significantly greater persistence, which decreased over time. Conclusions: Unmet needs and areas of intervention for healthcare systems aimed at improving the use of drugs for BHP/BPO-associated LUTS in the ASL TO4 Regione Piemonte were identified. Full article
(This article belongs to the Special Issue Medication Adherence and Beliefs About Medication: Second Edition)
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9 pages, 418 KiB  
Article
A Study on Types of Medication Adherence in Hypertension among Older Patients and Influencing Factors
by Sunmin Lee, Kyu-Hyoung Jeong, Seoyoon Lee and Hayoung Park
Healthcare 2022, 10(11), 2322; https://doi.org/10.3390/healthcare10112322 - 20 Nov 2022
Cited by 2 | Viewed by 2771
Abstract
Background: Hypertension has the characteristic that the risk of complications can be reduced through appropriate medication in daily life. Hence, it is important to consider practical measures to increase medication adherence, particularly among older patients. Methods: This study used the Korea Health Panel [...] Read more.
Background: Hypertension has the characteristic that the risk of complications can be reduced through appropriate medication in daily life. Hence, it is important to consider practical measures to increase medication adherence, particularly among older patients. Methods: This study used the Korea Health Panel 2020 data (Version 2.0.1), jointly conducted by Korea Institute for Health and Social Affairs and National Health Insurance. A total of 2300 patients with high blood pressure over 65 years of age were selected. In order to identify types of medication adherence in older hypertensive patients, and examine factors that influence the types, the Latent Profile Analysis (LPA) and logistic regression were performed. Results: The types of adherence groups were classified into two groups: an ‘adherence group’ (87.1%) and a ‘non-adherence group’ (12.9%). Furthermore, age, living alone, and depressive symptoms were identified as determinants of medication adherence type among older hypertensive patients. Conclusion: The significant impact of sociodemographic status (age, living alone, and depressive symptoms) on medication adherence among older hypertensive patients indicates the need to establish more specific empirical interventions based on each type’s characteristics. It is expected that this study will provide an in-depth understanding of factors associated with medication adherence among older patients with hypertension, which can support interventions tailored to the specific needs of those who are non-adherent. Full article
(This article belongs to the Special Issue Medication Adherence and Beliefs About Medication: Second Edition)
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9 pages, 800 KiB  
Article
Adherence to Antibiotic Prescription of Dental Patients: The Other Side of the Antimicrobial Resistance
by Francesco D’Ambrosio, Federica Di Spirito, Francesco De Caro, Antonio Lanza, Daniela Passarella and Ludovico Sbordone
Healthcare 2022, 10(9), 1636; https://doi.org/10.3390/healthcare10091636 - 27 Aug 2022
Cited by 15 | Viewed by 2148
Abstract
Since non-adherence to antibiotic therapy can cause several problems, including antimicrobial resistance (AMR) and treatment failures, the present study evaluated adherence to oral antibiotic therapy and AMR awareness among consecutively enrolled dental patients. Data concerning age, gender, socioeconomic status, education level, cohabitation, and [...] Read more.
Since non-adherence to antibiotic therapy can cause several problems, including antimicrobial resistance (AMR) and treatment failures, the present study evaluated adherence to oral antibiotic therapy and AMR awareness among consecutively enrolled dental patients. Data concerning age, gender, socioeconomic status, education level, cohabitation, and general health were retrieved from medical records. AMR awareness was investigated through direct questions and adherence to antibiotic treatment was assessed through a modified Italian version of the Morisky medical scale-8 items. Participants’ characteristics were analyzed in relation to treatment adherence and AMR, using a Χ2 independence test (significance level of α <0.1). Dental patients generally showed a low (51.82%) adherence to oral antibiotic therapy, and medium and high adherence was reported only by 29.37% and 18.81% of participants. Treatment adherence was similar in relation to participants’ gender and age but significantly lower in subjects with only secondary school graduation and higher in participants with higher education levels. Non-cohabitants were significantly more adherent than cohabitants. AMR awareness was declared by 42.15% of males and 38.70% of females: 56.52% of dental patients aware of AMR were 18–38 years old, 35.20% were 39–59 years old, and 26.95% were aged between 60 and 80. Further studies are needed to develop adequate strategies, expanding dental patients’ knowledge of AMR, thus optimizing the benefits and reducing the risks of antibiotic administration in dental patients. Full article
(This article belongs to the Special Issue Medication Adherence and Beliefs About Medication: Second Edition)
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14 pages, 302 KiB  
Article
Self-Medication Patterns during a Pandemic: A Qualitative Study on Romanian Mothers’ Beliefs toward Self-Treatment of Their Children
by Petruța Tarciuc, Doina Anca Pleșca, Alina Duduciuc, Nicoleta Gimiga, Elena Tătăranu, Valeria Herdea, Laura Mihaela Ion and Smaranda Diaconescu
Healthcare 2022, 10(9), 1602; https://doi.org/10.3390/healthcare10091602 - 23 Aug 2022
Cited by 2 | Viewed by 2049
Abstract
Self-medication represents a significant healthcare and health policy issue worldwide, both in developed and underdeveloped countries. Currently, the COVID-19 pandemic is considered a relevant context that could subtly trigger self-medication behavior because of limited access to health care services and the threat of [...] Read more.
Self-medication represents a significant healthcare and health policy issue worldwide, both in developed and underdeveloped countries. Currently, the COVID-19 pandemic is considered a relevant context that could subtly trigger self-medication behavior because of limited access to health care services and the threat of infection with the SARS-CoV-2 virus. While the previous research conducted with quantitative methodologies reported a dramatically increased rate of self-medication around the world, qualitative inquiries on the subjective experience with self-medicine remain scarce in medical and related fields of study. For this purpose, a qualitative study with semi-structured interviews was undertaken to better understand how Romanian mothers (n = 18) applied self-treatment with their children by avoiding medical advice during the COVID-19 pandemic. The results showed that the COVID-19 pandemic did not affect the prevalence of self-medicine among the pediatric population as parents achieved a degree of awareness of self-treatment of their children due to the general context of the outbreak of the COVID-19 pandemic. Full article
(This article belongs to the Special Issue Medication Adherence and Beliefs About Medication: Second Edition)
16 pages, 4935 KiB  
Article
A Participatory Sensing Study to Understand the Problems Older Adults Faced in Developing Medication-Taking Habits
by Maribel Valenzuela-Beltrán, Ángel G. Andrade, Katarzyna Stawarz and Marcela D. Rodríguez
Healthcare 2022, 10(7), 1238; https://doi.org/10.3390/healthcare10071238 - 02 Jul 2022
Viewed by 1518
Abstract
Past research has demonstrated that older adults tend to use daily activities as cues to remember to take medications. However, they may still experience medication non-adherence because they did not select adequate contextual cues or face situations that interfere with their medication routines. [...] Read more.
Past research has demonstrated that older adults tend to use daily activities as cues to remember to take medications. However, they may still experience medication non-adherence because they did not select adequate contextual cues or face situations that interfere with their medication routines. This work addresses two research questions: (1) How does the association that older adults establish between their daily routines and their medication taking enable them to perform it consistently? (2) What problems do they face in associating daily routines with medication taking? For 30 days, using a mixed-methods approach, we collected quantitative and qualitative data from four participants aged 70–73 years old about their medication taking. We confirm that older adults who matched their medication regimens to their habitual routines obtained better results on time-based consistency measures. The main constraints for using daily routines as contextual cues were the insertion of medication taking into broad daily routines, the association of multiple daily routines with medication taking, the lack of strict daily routines, and the disruption of daily routines. We argue that the strategies proposed by the literature for forming medication-taking habits should support their formulation by measuring patients’ dosage patterns and generating logs of their daily activities. Full article
(This article belongs to the Special Issue Medication Adherence and Beliefs About Medication: Second Edition)
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10 pages, 380 KiB  
Article
Attitude, Beliefs, and Use of Herbal Remedies by Patients in the Riyadh Region of Saudi Arabia
by Ahmad H. Alghadir, Amir Iqbal and Zaheen A. Iqbal
Healthcare 2022, 10(5), 907; https://doi.org/10.3390/healthcare10050907 - 13 May 2022
Cited by 7 | Viewed by 2642
Abstract
Background: The consumption of herbal medicines (HMs) is increasing worldwide, especially in developing countries. This study attempts to investigate and evaluate the patient’s perception with regard to the security of HMs, their attitudes towards the concomitant use of HMs with modern medicines, and [...] Read more.
Background: The consumption of herbal medicines (HMs) is increasing worldwide, especially in developing countries. This study attempts to investigate and evaluate the patient’s perception with regard to the security of HMs, their attitudes towards the concomitant use of HMs with modern medicines, and counseling about their use. Design: Self-administered questionnaire-based cross-sectional survey study. Setting: A self-administered structured questionnaire was administered to 200 patients who received HMs from four different government and private hospitals in the Riyadh region of Saudi Arabia, over a period of three months. Results: The response rate was 74.5%. Out of these, 76.83% of respondents reported using HMs in some form for a variety of conditions. There was no statistically significant relationship between various demographic characteristics and the use of herbs. The majority of the respondents (76.72%) reported using HMs without any professional supervision. This exposes them to the risk of harmful side effects and drug interactions. Conclusions: Physicians and pharmacists should work to provide evidence-based information about HMs to patients about effectiveness and side effects and be vigilant while writing prescriptions and dispensing drugs to them. Patient counseling and education about medication use are required to augment their awareness about their use. Full article
(This article belongs to the Special Issue Medication Adherence and Beliefs About Medication: Second Edition)
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Review

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9 pages, 253 KiB  
Review
The CFHealthHub Learning Health System: Using Real-Time Adherence Data to Support a Community of Practice to Deliver Continuous Improvement in an Archetypal Long-Term Condition
by Robert D. Sandler and Martin J. Wildman
Healthcare 2023, 11(1), 20; https://doi.org/10.3390/healthcare11010020 - 21 Dec 2022
Cited by 2 | Viewed by 1448
Abstract
CFHealthHub is a learning health system active in over 50% of adult CF Centres in England, supporting people with CF to develop habits of self-care around adherence to preventative inhaled therapy. This is achieved through the delivery of a behaviour change intervention, alongside [...] Read more.
CFHealthHub is a learning health system active in over 50% of adult CF Centres in England, supporting people with CF to develop habits of self-care around adherence to preventative inhaled therapy. This is achieved through the delivery of a behaviour change intervention, alongside collection of objective adherence data. As is common to long-term conditions, adherence to prescribed therapy is low, despite clear evidence of beneficial long-term impact on outcomes. This article explains how CFHealthHub is underpinned by coherent conceptual frameworks. We discuss how application of implementation and quality improvement strategies has facilitated CFHealthHub’s progression from a pilot study to a large, randomised control trial and now to a learning health system, becoming embedded within routine care. CFHealthHub is now able to support real-time health technology assessments, quality improvement and research trials and is in the process of being implemented in routine clinical care across participating centres. Full article
(This article belongs to the Special Issue Medication Adherence and Beliefs About Medication: Second Edition)
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