Diagnostic Modalities in Critical Care -Volume 2

A special issue of Diagnostics (ISSN 2075-4418). This special issue belongs to the section "Point-of-Care Diagnostics and Devices".

Deadline for manuscript submissions: closed (28 April 2023) | Viewed by 1754

Special Issue Editors

Special Issue Information

Dear Colleagues,

Early screening and recognition of severe medical and surgical illnesses, advanced and rush prehospital care of urgent conditions, organized immediate care in trauma centers and development of in-hospital rapid response teams lead to an increase of intensive care patients and survival of severe conditions in the last few decades. In the intensive care setting, bedside diagnostic tools are essential for good quality of care, early recognition of complications and treatment of critically ill patients. Due to very unstable patients, complex monitoring and oft diverse robust organ support systems (extracorporeal heart, lungs kidneys, liver support, etc.) diagnostics need to be brought to the patient's bed. Intensive care treatment of medical patients, patients after cardiothoracic or major abdominal surgery, polytraumatized and all other critically ill patients is currently incomprehensible without continuously sophisticated monitoring, bedside ultrasonography, diverse radiologic diagnostic techniques, point of care coagulation management, and laboratory and other diagnostic modalities. In the time of the COVID-19 pandemic, the information on the use of different radiologic techniques, on revolutionary use of ultrasonography in lungs investigation, diverse laboratory tests primary for COVID-19 diagnosis and furthermore for early recognition of potentially fatal complications and their prevention is increasing and should be properly addressed.

Bedside diagnostic techniques are rapidly emerging as an important and irreplaceable tool in the hands of intensive care physicians, therefore the main goal of this second volume Special Issue is to update on and summarize diverse diagnostic modalities and diagnostic approaches in the intensive care setting, specially focusing on the point of care approach.

Dr. Sasa Rajsic
Dr. Benedikt Treml
Guest Editors

Manuscript Submission Information

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Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Diagnostics is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2600 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.


  • intensive care
  • critical care
  • critically ill
  • point of care
  • bedside
  • monitoring
  • ultrasonography
  • radiologic diagnostic
  • coagulation
  • COVID-19
  • emergency
  • prehospital

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Published Papers (1 paper)

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12 pages, 599 KiB  
Brixia Chest X-ray Score, Laboratory Parameters and Vaccination Status for Prediction of Mortality in COVID-19 Hospitalized Patients
by Jusuf A. Nukovic, Valentina Opancina, Nebojsa Zdravkovic, Nikola Prodanovic, Ana Pejcic, Miljan Opancina, Jasmin J. Nukovic, Radisa Vojinovic, Dragan Dulovic, Fehim Jukovic, Nedim Hamzagic, Merisa Nukovic and Nenad V. Markovic
Diagnostics 2023, 13(12), 2122; https://doi.org/10.3390/diagnostics13122122 - 20 Jun 2023
Viewed by 1327
Chest X-ray has verified its role as a crucial tool in COVID-19 assessment due to its practicability, especially in emergency units, and Brixia score has proven as a useful tool for COVID-19 pneumonia grading. The aim of our study was to investigate correlations [...] Read more.
Chest X-ray has verified its role as a crucial tool in COVID-19 assessment due to its practicability, especially in emergency units, and Brixia score has proven as a useful tool for COVID-19 pneumonia grading. The aim of our study was to investigate correlations between main laboratory parameters, vaccination status, and Brixia score, as well as to confirm if Brixia score is a significant independent predictor of unfavorable outcome (death) in COVID-19 patients. The study was designed as a cross-sectional multicentric study. It included patients with a diagnosed COVID-19 infection who were hospitalized. This study included a total of 279 patients with a median age of 62 years. The only significant predictor of unfavorable outcome (death) was Brixia score (adjusted odds ratio 1.148, p = 0.022). In addition, the results of the multiple linear regression analysis (R2 = 0.334, F = 19.424, p < 0.001) have shown that male gender (B = 0.903, p = 0.046), severe COVID-19 (B = 1.970, p < 0.001), and lactate dehydrogenase (B = 0.002, p < 0.001) were significant positive predictors, while albumin level (B = −0.211, p < 0.001) was a significant negative predictor of Brixia score. Our results provide important information about factors influencing Brixia score and its usefulness in predicting the unfavorable outcome (death) of COVID-19 patients. These findings have clinical relevance, especially in epidemic circumstances. Full article
(This article belongs to the Special Issue Diagnostic Modalities in Critical Care -Volume 2)
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