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Cosmetics
Special Issues
Treatment for Anti-aging and Rejuvenation
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Treatment for Anti-aging and Rejuvenation

A special issue of Cosmetics (ISSN 2079-9284).

Deadline for manuscript submissions: 20 September 2024 | Viewed by 11878

Special Issue Editor

Dr. Ji Yeon Hong

E-Mail Website
Guest Editor
Department of Dermatology, Chungnam National University Sejong Hospital, Chungnam National University College of Medicine, Sejong, Republic of Korea
Interests: cosmetic dermatology; filler; botulinum toxin; rejuvenation; anti-aging; cosmeceuticals; laser

Special Issue Information

Dear Colleagues,

The role of healthcare is now shifting beyond disease treatment to focus on disease prevention, and it is even advancing into technologies that can reverse the aging process. Consequently, anti-aging and skin rejuvenation have become emphasized areas within the fields of dermatology, plastic surgery, and cosmetics. In this Special Issue, titled "Treatment for Anti-aging and Rejuvenation", we warmly invite your submissions of research and review papers encompassing topics such as cosmeceuticals, energy-based devices, laser modalities, surgical interventions, and more. Furthermore, we look forward to the sharing of up-to-date knowledge in the fields of cosmetology, dermatology, aesthetic dermatology, and plastic surgery.

Dr. Ji Yeon Hong
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Cosmetics is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 1800 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • dermatology
  • cosmetology
  • energy-based devices
  • laser
  • rejuvenation
  • anti-aging
  • plastic surgery
  • cosmetic surgery
  • face-lift
  • fat transfer
  • dermal fillers
  • botulinum toxin
  • skin boosters

Published Papers (6 papers)

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Research

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11 pages, 1186 KiB  
Article
1064 nm Q-Switched Fractional Laser for Transcutaneous Delivery of a Biostimulator: Efficacy and Safety Outcomes of a Split-Face Study
by Francesco Moro, Elisa Camela, Tonia Samela, Lia Pirrotta, Maria Beatrice Pupa, Tiziano Zingoni, Irene Fusco and Laura Colonna
Cosmetics 2024, 11(1), 14; https://doi.org/10.3390/cosmetics11010014 - 23 Jan 2024
Cited by 1 | Viewed by 1643
Abstract
Background: Laser-assisted drug delivery is a promising strategy that enhances topical treatment by increasing cutaneous permeation and reducing side effects. In cosmetic settings, the efficacy and safety profiles of a treatment must meet the need of a painless procedure with fast recovery. In [...] Read more.
Background: Laser-assisted drug delivery is a promising strategy that enhances topical treatment by increasing cutaneous permeation and reducing side effects. In cosmetic settings, the efficacy and safety profiles of a treatment must meet the need of a painless procedure with fast recovery. In this context, Q-switched laser appears promising as it can open cutaneous pores without creating a carbonisation barrier. Methods: A split-face study on patients presenting for cosmetic procedures at IDI-IRCCS, Rome (30 September–18 October 2023), was conducted. Pan-facial Q-Switched laser was followed by a topical biostimulator applied on half of the face. Post-procedure local reactions were recorded together with patients’ perceptions. Cutaneous elasticity and hydration were assessed at baseline and three-week follow-up. The Skindex17 questionnaire evaluated the procedure’s impact on patients’ life quality. Also, participants and physicians expressed satisfaction with the treatment. Results: The procedure was well tolerated by patients; local reactions include transitory erythema, superficial bleeding, and oedema, none of which had an impact on daily life. An improvement in skin quality was documented objectively and subjectively by patients and physicians. Conclusion: Q-switched lasers emerge as promising devices for drug delivery, especially for cosmetic reasons. Indeed, the low risk of local reactions together with a remarkable increase in cutaneous permeation make this a suitable strategy for cosmetic procedures. Full article
(This article belongs to the Special Issue Treatment for Anti-aging and Rejuvenation)
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21 pages, 6050 KiB  
Article
An Assessment of the Effectiveness and Safety of ULTRACOL100 as a Device for Restoring Skin in the Nasolabial Fold Region
by Thuy-Tien Thi Trinh, Pham Ngoc Chien, Linh Thi Thuy Le, Nguyen Ngan-Giang, Pham Thi Nga, Sun-Young Nam and Chan-Yeong Heo
Cosmetics 2024, 11(1), 4; https://doi.org/10.3390/cosmetics11010004 - 25 Dec 2023
Viewed by 2460
Abstract
One of the most notable signs of an aging face is the nasolabial folds (NLFs), which often diminish emotional well-being and self-confidence. To address this concern, many people seek solutions to improve their appearance, often turning to fillers. The ULTRACOL100 device, a tissue [...] Read more.
One of the most notable signs of an aging face is the nasolabial folds (NLFs), which often diminish emotional well-being and self-confidence. To address this concern, many people seek solutions to improve their appearance, often turning to fillers. The ULTRACOL100 device, a tissue restoration material, has been previously investigated and shown to exhibit significant efficacy in both in vitro and in vivo studies. In this research, we aim to explore the safety and effectiveness of the clinical trial of ULTRACOL100 in improving the skin in the NLF area over an 8-week observation period. Male and Female adults with nasolabial folds received two injections of ULTRACOL100, with a 4-week interval between treatments, on one side of their faces. On the other side, they received control materials (REJURAN®, JUVELOOK®, or HYRONT®). The assessment of skin improvement in the nasolabial fold area for each subject took place before and four weeks after each application. Various skin parameters, such as roughness, elasticity, moisture, transparency, trans-epidermal water loss, tone, radiance, skin pore size, and skin density, were measured to evaluate the outcomes. The application of the ULTRACOL100 device significantly reduced the skin roughness, the trans-epidermal water loss, and the skin pore size and increased the skin’s elasticity and internal elasticity, as well as the skin’s moisture, transparency, skin tone, radiance, and density. This study comprehensively investigates the effectiveness and safety of the ULTRACOL100 device, comparing it with three commercial products (REJURAN®, JUVELOOK®, and HYRONT®). The ULTRACOL100 device showed comparable performance in improving the appearance of the NLF area among this study subjects. Full article
(This article belongs to the Special Issue Treatment for Anti-aging and Rejuvenation)
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13 pages, 1600 KiB  
Article
Simultaneous Skin Rejuvenation in Patients Undergoing Medical Treatment for Actinic Keratosis and Non-Melanoma Skin Cancer: A Case Series Analysis
by Nadia Sciamarrelli, François Rosset, Sara Boskovic, Silvia Borriello, Luca Mastorino, Simone Ribero, Pietro Quaglino and Paolo Broganelli
Cosmetics 2024, 11(1), 3; https://doi.org/10.3390/cosmetics11010003 - 25 Dec 2023
Viewed by 1925
Abstract
This original article presents the findings of a comprehensive case series, shedding light on the efficacy of diverse treatment modalities for managing precancerous and cancerous skin lesions and their remarkable rejuvenation effects on the skin. A particular focus is placed on the promising [...] Read more.
This original article presents the findings of a comprehensive case series, shedding light on the efficacy of diverse treatment modalities for managing precancerous and cancerous skin lesions and their remarkable rejuvenation effects on the skin. A particular focus is placed on the promising outcomes achieved through the application of a combination treatment involving 5-Fluorouracil (5-FU) and salicylic acid, which demonstrates enduring and noteworthy results. Furthermore, alternative therapeutic approaches, including 5-FU monotherapy, Methyl aminolevulinate–photodynamic therapy (MAL-PDT), and the combination of Imiquimod therapy with MAL-PDT, exhibit substantial potential for patients seeking non-surgical solutions. These treatments manifest as valuable tools in improving skin texture and mitigating the effects of photodamage. Nevertheless, the intricate interplay between the chosen treatment, the extent of photodamage, and individual patient characteristics, with a particular emphasis on age, necessitates long-term follow-up to gauge treatment outcomes and the likelihood of lesion recurrence. Notably, these treatments are associated with a significant degree of inflammation, igniting curiosity regarding enhanced skin cellular turnover and the potential for a more youthful skin appearance. Our findings accentuate the promise of topical fluorouracil (5-FU) and photodynamic therapy (PDT) in combating photoaging among patients with actinic keratoses. However, a need for further in-depth research is evident to unravel the nuanced relationships between these treatments, the severity of photodamage, and the influence of patient-specific factors. Such comprehensive investigations are instrumental in optimizing patient care and outcomes, offering a holistic approach to managing photodamage within the context of actinic keratoses. This work, when combined with existing literature, provides valuable insights and serves as a catalyst for future research to fully unlock the potential of these treatments, ultimately enhancing the quality of patient care. Full article
(This article belongs to the Special Issue Treatment for Anti-aging and Rejuvenation)
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Review

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12 pages, 294 KiB  
Review
Current Knowledge and Regulatory Framework on the Use of Hyaluronic Acid for Aesthetic Injectable Skin Rejuvenation Treatments
by Jenny Allen and Kalliopi Dodou
Cosmetics 2024, 11(2), 54; https://doi.org/10.3390/cosmetics11020054 - 03 Apr 2024
Viewed by 1445
Abstract
Dermal injections of hyaluronic acid gel for aesthetic skin rejuvenation are becoming increasingly popular nowadays. Although these products are classified as medical devices, the regulations on their administration by licensed practitioners are still weak, whereas their manufacturers increasingly highlight and advertise the cellular [...] Read more.
Dermal injections of hyaluronic acid gel for aesthetic skin rejuvenation are becoming increasingly popular nowadays. Although these products are classified as medical devices, the regulations on their administration by licensed practitioners are still weak, whereas their manufacturers increasingly highlight and advertise the cellular effects that underpin the efficacy of these injections. In this review, we discuss all current knowledge on the mode of action of dermally injected hyaluronic acid and the potential toxicological implications, especially from crosslinked gels, in conjunction with the current global regulations. We also highlight the urgent need for further research to elucidate the therapeutic implications and underscore the imperative need for robust regulatory frameworks to safeguard public health. We conclude that dermal injections of hyaluronic acid have several therapeutic implications that warrant further research and that strict regulations must be applied to their manufacture/quality control and the required qualifications of licensed aesthetic injectors. Full article
(This article belongs to the Special Issue Treatment for Anti-aging and Rejuvenation)
21 pages, 1253 KiB  
Review
Promising Functions of Novel Vitamin D Derivatives as Cosmetics: A New Fountain of Youth in Skin Aging and Skin Protection
by Zorica Janjetovic and Andrzej T. Slominski
Cosmetics 2024, 11(2), 37; https://doi.org/10.3390/cosmetics11020037 - 01 Mar 2024
Cited by 1 | Viewed by 2332
Abstract
Vitamin D is a natural photoproduct that has many beneficial effects on different organs, including skin. Active forms of vitamin D and its derivatives exert biological effects on skin cells, thus maintaining skin homeostasis. In keratinocytes, they inhibit proliferation and stimulate differentiation, have [...] Read more.
Vitamin D is a natural photoproduct that has many beneficial effects on different organs, including skin. Active forms of vitamin D and its derivatives exert biological effects on skin cells, thus maintaining skin homeostasis. In keratinocytes, they inhibit proliferation and stimulate differentiation, have anti-inflammatory properties, act as antioxidants, inhibit DNA damage and stimulate DNA repair after ultraviolet (UV) exposure. In melanocytes, they also inhibit cell proliferation, inhibit apoptosis and act as antioxidants. In fibroblasts, they inhibit cell proliferation, affect fibrotic processes and collagen production, and promote wound healing and regeneration. On the other hand, skin cells have the ability to activate vitamin D directly. These activities, along with the projected topical application of vitamin D derivatives, are promising for skin care and photo protection and can be used in the prevention or possible reversal of skin aging. Full article
(This article belongs to the Special Issue Treatment for Anti-aging and Rejuvenation)
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Other

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10 pages, 3457 KiB  
Case Report
Using 3D Imaging to Preoperatively Plan Facelift Procedures for the Lower Third of the Face and Neck
by Anastasiya S. Borisenko, Valentin I. Sharobaro, Alexey E. Avdeev, Nigora S. Burkhonova and Anastasiya O. Fisun
Cosmetics 2024, 11(1), 28; https://doi.org/10.3390/cosmetics11010028 - 11 Feb 2024
Viewed by 1552
Abstract
The pursuit of youth and attractiveness is a fundamental desire in contemporary society. For many individuals, the appearance of visible signs of aging, such as skin laxity, gravitational changes in facial and neck soft tissues, and loss of harmonious proportions, can be psychologically [...] Read more.
The pursuit of youth and attractiveness is a fundamental desire in contemporary society. For many individuals, the appearance of visible signs of aging, such as skin laxity, gravitational changes in facial and neck soft tissues, and loss of harmonious proportions, can be psychologically distressing. The choice of effective methods for addressing these changes depends on their specific characteristics, the patient’s anatomical features, and the type of facial aging. The introduction of 3D imaging to determine the hyoid bone level, the volume of soft tissue structures in the cervico-mental area, ptosis of subplatysmal structures, and the volume of submandibular glands, in addition to ultrasound study of the submental projection at the preoperative stage, are key for making the best decisions regarding preoperative planning. This case report aims to illustrate how modern imaging techniques are a fundamental part of the preoperative assessment of the mid and lower third of the face to ensure the most favorable aesthetic outcomes for each patient. Full article
(This article belongs to the Special Issue Treatment for Anti-aging and Rejuvenation)
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