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Children
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Current Challenges in Pediatric Gastrointestinal Diseases
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Current Challenges in Pediatric Gastrointestinal Diseases

A special issue of Children (ISSN 2227-9067).

Deadline for manuscript submissions: 15 August 2024 | Viewed by 2865

Special Issue Editors

Dr. Marco Manfredi

E-Mail Website
Guest Editor
Maternal and Child Department, Azienda USL-IRCCS di Reggio Emilia, Sant’Anna Hospital, Castelnovo ne’ Monti, Italy
Interests: Helicobacter pylori; acute gastroenteritis; functional gastrointestinal disorders; celiac disease; gastroesophageal reflux disease
Dr. Madhur Ravikumara

E-Mail Website
Guest Editor
Department of Gastroenterology, Perth Children's Hospital, Perth, WA, Australia
Interests: inflammatory bowel disease; coeliac disease; malabsorption; gastrostomy and liver diseases in children

Special Issue Information

Dear Colleagues,

Gastrointestinal diseases include a wide range of pathological disorders affecting children and adolescents all over the world. This group of disorders represents one of the more frequent reasons for the requirement of paediatric consultation both in outpatient and urgent inpatient settings. In the last few years, the knowledge related to pathogenesis, diagnosis and treatment has greatly improved, and great progress is also being made regarding the follow-up of chronic diseases with the aim of improving the patients’ quality of life. The aim of this Special Issue is to discuss and present several aspects of gastrointestinal disorders in paediatrics with the intent of increasing our knowledge and awareness of these conditions.

We look forward to receiving your contributions.

This Special Issue welcomes original research articles as well as review articles and case reports focusing on recent advances in gastrointestinal diseases in children and adolescents.

Dr. Marco Manfredi
Dr. Madhur Ravikumara
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Children is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2400 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • children
  • acute diarrhoea
  • abdominal pain
  • gastrointestinal infections
  • Helicobacter pylori
  • inflammatory bowel diseases

Published Papers (2 papers)

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Research

13 pages, 473 KiB  
Article
Characteristics of the Inflammatory Bowel Disease in Children: A Croatian Single-Centre Retrospective Study
by Ivan Pivac, Antonia Jelicic Kadic, Ranka Despot, Vanda Zitko, Darija Tudor, Edita Runjic and Josko Markic
Children 2023, 10(10), 1677; https://doi.org/10.3390/children10101677 - 11 Oct 2023
Cited by 2 | Viewed by 915
Abstract
Inflammatory bowel diseases (IBDs), encompassing ulcerative colitis (UC) and Crohn’s disease (CD), are chronic gastrointestinal disorders often diagnosed in youth, presenting unique features compared to adult-onset cases. We aimed to profile pediatric IBD patients in Croatia through a retrospective analysis of children up [...] Read more.
Inflammatory bowel diseases (IBDs), encompassing ulcerative colitis (UC) and Crohn’s disease (CD), are chronic gastrointestinal disorders often diagnosed in youth, presenting unique features compared to adult-onset cases. We aimed to profile pediatric IBD patients in Croatia through a retrospective analysis of children up to 18 years old diagnosed with IBD at the University Hospital of Split from 1 January 2012, to 31 December 2021, utilizing data collected during hospitalization for diagnosis. Over a decade, 107 children were diagnosed, with 43.9% having UC, 55.1% CD, and 0.9% IBD-unclassified. Median age at diagnosis was 14.1 years, with UC patients being older (14.8 vs. 13.7 years, p = 0.044). Males constituted 60.7% of patients. Median symptom duration was 2.0 months, with CD patients experiencing a longer diagnostic delay (3.0 vs. 2.0 months, p = 0.003). The median incidence rate was 9.89 (95% CI 5.93–13.84) per 100,000 children/year, varying across age groups. Median (IQR) BMI z-score was −0.34 (−0.97–0.45). Common symptoms included diarrhea (60.7%) and abdominal pain (50.5%), with rectal bleeding more prevalent in UC (72.3% vs. 32.2%, p < 0.001). While our study offers valuable insights into pediatric IBD in Croatia, further prospective research is needed to clarify disease progression and development. Full article
(This article belongs to the Special Issue Current Challenges in Pediatric Gastrointestinal Diseases)
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10 pages, 252 KiB  
Article
Social and Environmental Determinants of Diarrheal Diseases among Children under Five Years in Epworth Township, Harare
by Sandra Chari, Thokozani Patrick Mbonane and Renay Helouise Van Wyk
Children 2023, 10(7), 1173; https://doi.org/10.3390/children10071173 - 06 Jul 2023
Cited by 1 | Viewed by 1414
Abstract
Children five years or younger in low- and middle-income countries (LMICs) are severely affected by diarrheal disease, especially in the sub-Saharan region. Hence, this study aimed at determining the prevalence and determinants of diarrhoea disease among children under 5 years in Epworth Township, [...] Read more.
Children five years or younger in low- and middle-income countries (LMICs) are severely affected by diarrheal disease, especially in the sub-Saharan region. Hence, this study aimed at determining the prevalence and determinants of diarrhoea disease among children under 5 years in Epworth Township, Zimbabwe. A descriptive cross-sectional study was conducted at a local clinic in Epworth Township, Harare. A convenience sampling strategy was used to recruit study participants for participation, and 386 children were enrolled in the study. The majority were male children (n = 229; 59.3%), whereas there were more female caregivers (n = 370; 95.9%) than male caregivers (n = 16; 4.1%). The prevalence of diarrhoea disease in the study was 25.1%. The determinants associated with diarrhoea were being partially vaccinated (AOR 2.38, CI: 95% 2.80–8.22), collecting water more than 1 kilometre from a household (AOR 4.55; CI: 95% 2.10–9.85), and using untreated water (AOR 6.22; CI: 95% 2.13–18.20). The age of the caregiver (being older than 21) and using a clean water container (AOR 0.05; CI: 95% 0.02–0.13) were protective factors. Provision of primary health care, especially the prevention of a disease through immunization and rendering environmental health services, could reduce the prevalence of diarrhoea in disadvantaged townships. Full article
(This article belongs to the Special Issue Current Challenges in Pediatric Gastrointestinal Diseases)
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