Synapses: Molecular Organization, Regulation and Synaptic Function
A special issue of Cells (ISSN 2073-4409).
Deadline for manuscript submissions: 31 May 2024 | Viewed by 191
Special Issue Editor
Interests: synaptic transmission; synaptic plasticity; protein phosphatases; phosphorylation; CNS myelination; learning and memory; intellectual disability; epilepsy
Special Issue Information
Dear Colleagues,
Synapses are highly organized subcellular compartments specializing in synaptic transmission and many forms of synaptic plasticity. Glutamate receptors, GABAA receptors, signaling molecules, and cell adhesion molecules constitute essential components in supporting synaptic function. Efficient signal transduction at synapses requires scaffolding proteins which bring signaling molecules in close physical proximity to their effectors, forming a signaling center. The activity-dependent reorganization of signaling molecules to the physical proximity of their effector via trafficking/regulation of their scaffolding proteins is critical for the modification of multiple classes of proteins.
Understanding how signaling molecules are regulated by their scaffolding proteins and other modulators will help elucidate the panoply of mechanisms that underlie synaptic plasticity. Moreover, understanding how this organization is perturbed in different neurological diseases will help identify putative therapeutic pathways. We invite research or review articles on any subjects, including liquid-liquid phase separation (LLPS), related to molecular organization and its regulation associated with synapse function and neural plasticity.
Dr. Houhui Xia
Guest Editor
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Cells is an international peer-reviewed open access semimonthly journal published by MDPI.
Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2700 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
Keywords
- synapse
- glutamate
- GABA
- neurotransmitter receptor
- scaffolding protein
- ion channel
- kinase
- phosphatase
- cell adhesion molecule
