Pulmonary Vascular Diseases in Extreme Environments: What Is Our Current Knowledge?
A special issue of Cells (ISSN 2073-4409). This special issue belongs to the section "Cells of the Cardiovascular System".
Deadline for manuscript submissions: 31 August 2024 | Viewed by 158
Special Issue Editors
Interests: pulmonary hypertension; lung fibrosis; high-altitude medicine
Interests: pulmonary hypertension; right ventricular hypertrophy; high altitude medicine and physiology
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
Pulmonary hypertension (PH) is a severe and potentially deadly pulmonary vascular disorder characterized by deregulated pulmonary vasoconstriction and pulmonary vascular remodeling. Pulmonary vascular remodeling appears due to abnormal cellular processes, such as the increased proliferation and reduced apoptosis of the pulmonary vascular cells. High-altitude milieu is a well-known extreme environmental location, characterized by chronic hypoxic conditions, which can cause the development of high-altitude-induced PH. Another extreme environmental condition, such as prolonged cold exposure, has also been described to induce the development of cold-induced PH. Despite the existing literature about hypoxia and cold-induced pulmonary vascular diseases, the precise and profound cellular and molecular mechanisms are still not fully revealed and established. Therefore, we invite our colleagues to contribute to our Special Issue by submitting their manuscripts as either original works or review articles with a focus on in vivo and in vitro studies. Finally, manuscripts dealing with human patients are strongly welcome.
Dr. Djuro Kosanovic
Dr. Akylbek Sydykov
Guest Editors
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Keywords
- pulmonary vascular diseases
- pulmonary hypertension
- pulmonary vascular vasoconstriction
- pulmonary vascular remodeling
- high altitude
- hypoxia
- cold exposure
- cold environment
- cellular and molecular mechanisms
