Novel Concepts in Aptamer Selection, Modification and Integration into Sensing Platforms

A special issue of Biosensors (ISSN 2079-6374). This special issue belongs to the section "Biosensor and Bioelectronic Devices".

Deadline for manuscript submissions: closed (31 January 2022) | Viewed by 467

Special Issue Editors

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Guest Editor
Applied Biophysics and Surface Science Group, Bio-Medical Research Foundation of the Academy of Athens (BRFAA), Athens, Greece
Interests: biointerfaces; aptamers; surface (bio)functionalization; material-independent chemis-tries; biosensors; lab-on-a chip; NEMS; microfluidics; point-of-need; medical diagnostics; food safety; drug screening; environmental monitoring
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Guest Editor
1. Department of Applied Physics, National Technical University of Athens, 10682 Athens, Greece
2. Department of Biomedical Engineering, University of West Attica, 122 43 Athens, Greece
Interests: nanotechnology; materials science; sensing technology & amp; thin films fabrication/characterization (sputtering, pvd, ald)

Special Issue Information

Dear Colleagues,

You are kindly invited to submit original research and review articles to this new Special Issue dedicated to the most recent developments in the field of aptamers and aptasensors. It has been almost 30 years since the invention of systematic evolution of ligands by exponential enrichment (SELEX) methodology and the description of the first aptamers, but unfortunately, aptamer development still lags behind the progress made in the analytical methodologies that employ them. This Special Issue aims to gather the latest advances in aptamer selection techniques and the rational or semirational introduction of modifications to improve their affinity and specificity and enhance their performance. It also aims to showcase novel applications of aptamers alone or in combination with nanomaterials in fields where they are already traditionally deployed (environmental and food monitoring), but also in emerging ones such as medical diagnostics and therapeutics, with a special emphasis on their employment in complex matrices with minimal sample preparation. It is my hope that this Special Issue will provide a forum for the exchange of ground-breaking ideas on aptamers and their applications and will inspire the scientific community to further investigate aptamer structure, rational design, and integration into biosensing platforms. 

Dr. George Tsekenis
Dr. Evangelos Skotadis
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Biosensors is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2700 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.


  • Aptamers
  • Aptazymes
  • Post-selection aptamer modifications
  • Rational design
  • Environmental monitoring
  • Food safety and quality
  • Medical diagnostics
  • Therapeutics
  • Matrix effects
  • Continuous monitoring

Published Papers

There is no accepted submissions to this special issue at this moment.
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