Special Issue "Macrophages in Cardio-Renal Diseases"

A special issue of Biomedicines (ISSN 2227-9059). This special issue belongs to the section "Endocrinology and Metabolism Research".

Deadline for manuscript submissions: 30 November 2023 | Viewed by 181

Special Issue Editors

1. Department of Medicine, David Geffen School of Medicine at University of California, Los Angeles, CA 90095, USA
2. Department of Internal Medicine, Charles R. Drew University of Medicine and Science, Los Angeles, CA 90059, USA
Interests: cardiovascular disease; atherosclerosis; inflammation; macrophage
Dr. Yuchen Wang
E-Mail Website
Guest Editor
Department of Medicine, David Geffen School of Medicine at University of California, Los Angeles, CA 90095, USA
Interests: immune microenvironment; cell-cell communication; inflammation and bioinformatics

Special Issue Information

Dear Colleagues,

Macrophages play a significant role in cardio-renal diseases, including atherosclerosis, heart failure, hypertension, and chronic kidney disease. They contribute to the development and progression of these conditions through inflammation, tissue remodeling, and fibrosis. In atherosclerosis, macrophages form lipid-laden foam cells within arterial walls, thus leading to plaque formation. They promote myocardial inflammation and fibroblast activation, contributing to adverse remodeling in heart failure. Macrophages also play a role in hypertension by causing renal inflammation and vascular dysfunction. In chronic kidney disease, macrophages contribute to renal inflammation, fibrotic remodeling, and impaired tissue repair. Targeting macrophage activities and interactions holds promise for therapeutic interventions in cardio-renal diseases, offering opportunities to mitigate inflammation, improve vascular function, and preserve renal integrity. Therefore, this issue will focus on recent findings uncovering new aspects of macrophage biology in cardio-renal diseases.

Dr. Satyesh K. Sinha
Dr. Yuchen Wang
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

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Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2600 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.


  • cardiovascular disease and macrophages
  • macrophage-mediated inflammation
  • macrophage phenotypes
  • macrophage senescence
  • macrophage proliferation and survival
  • macrophages and lipid metabolism

Published Papers

This special issue is now open for submission.
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