Epithelial–Mesenchymal Transition: Mechanisms and Roles
A special issue of Biomedicines (ISSN 2227-9059). This special issue belongs to the section "Cell Biology and Pathology".
Deadline for manuscript submissions: closed (31 December 2023) | Viewed by 197
Special Issue Editors
Interests: epithelial/endothelial-mesenchymal transition; inflammation; antioxidants; tissue injury and remodeling
Interests: physiology; neuroscience; neurology; ophthalmology
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleague,
This Special Issue, “Epithelial–Mesenchymal Transition (EMT): Mechanisms and Roles” will mainly focus on the principal roles that EMT plays in disease development, cancer progression and metastases. EMT is a form of epithelial dysfunction wherein epithelial cells lose their epithelial identity and function and in turn acquire mesenchymal-like markers and function, a process that is prominent in the pathogenesis of many diseases, including fibrosis and cancer. Notably, the induction of EMT requires the coordinated action of multiple stimuli, such as exposure to cytokines, growth factors, oxidative stress, and inflammatory signals. Therefore, understanding the dynamic crosstalk between these cells may help identify new therapeutic targets for fibrosis, cancer, and even cancer metastasis. Thus, we consider this topic to be of particular interest as new knowledge can help prevent treatment failure and contrast disease progression. We invite authors to submit original research and review articles focusing on the epithelial to mesenchymal transition and cellular plasticity in disease development, cancer progression and metastases, and their potentiality in diagnosis and target therapy.
Potential topics including but not limited to:
- EMT/MET in disease development, cancer progression and metastasis.
- Omics in EMT/MET.
- EMT proteins as diagnostic biomarkers and precision therapy—New methodology.
Dr. Chen-Wei Liu
Dr. Xiaokuang Ma
Guest Editors
Manuscript Submission Information
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Keywords
- Epithelial–Mesenchymal Transition
- oxidative stress
- inflammatory signals
- fibrosis
- cancer metastasis
- precision therapy
