Pathogenesis and Novel Diagnostics in Juvenile Idiopathic Arthritis and Other Rheumatic Diseases

Dear Colleagues,

Paediatric rheumatic diseases refer to a heterogeneous collection of autoimmune or autoinflammatory forms of musculoskeletal, arthritic, and connective tissue disorders that can develop in childhood. The most common types of these diseases are juvenile idiopathic arthritis and other rheumatic diseases (such as dermatomyositis or systemic lupus erythematosus). These diseases  can affect children of any age and any ethnic background, and being diagnosed too late or poorly treated may contribute to the disability of an afflicted child, due to disturbances in the structure and function of the osteoarticular and muscle system. Hence, the prompt detection of structural disorders of the articular cartilage would allow clinicians to initiate appropriate therapies, which is essential for the course of the arthropathy in question. Too late an application of appropriate treatment, resulting from the lack of specific diagnostic biomarkers, may result in the perpetuation of pathological changes in the motor system in patients, or the development of systemic disorders, especially in those with high disease activity who require an aggressive therapy.

It is therefore crucial that we continue to research the pathogenesis of paediatric rheumatic diseases, seeking new biomarkers of the diseases and effective therapeutic methods. We invite researchers to submit original works or review articles covering significant development in the pathogenesis of juvenile idiopathic arthritis and other rheumatic diseases, as well as novel diagnostic and therapeutic methods.

Prof. Dr. Katarzyna Winsz-Szczotka
Dr. Kornelia Kuźnik-Trocha
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Biomedicines is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2600 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

• juvenile idiopathic arthritis
• juvenile dermatomyositis
• systemic lupus erythematosus
• musculoskeletal pain syndromes
• local and systemic scleroderma
• Kawasaki disease
• diagnosis and treatment
• biomarkers
• cartilage
• matrix
• inflammation
• extra-articular manifestations
• immune response