Role of Bone Marrow Niche in Haematological Cancers
A special issue of Biomedicines (ISSN 2227-9059). This special issue belongs to the section "Cancer Biology and Oncology".
Deadline for manuscript submissions: 31 July 2024 | Viewed by 193
Special Issue Editor
Interests: cellular biology; mesenchymal stem cells; bone marrow microenvironment; cancer immunology
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
Blood cancers include leukaemia, lymphoma, multiple myeloma, myelodysplastic and myeloproliferative syndromes. These cancers are extremely challenging with great patient variability in molecular and clinical profiles. The treatment failure and adverse side effects of intensive therapies, particularly bone marrow transplantation, are other demands to increase research in this field. Bone marrow niches for these haematological cancers include different cells of blood and stromal types. Many genetics and functional cell studies have focused on malignant blast cells and cancer immunology. However, there is a need for novel research to understand the complicated pathogenesis of these cancers and identify new roles of related molecules and signalling. Such knowledge is needed to improve current treatment options and develop new therapeutic tools.
This Special Issue will cover a wide range of research on the cellular and molecular mechanisms of blood cancers, particularly those taking place within the bone marrow microenvironment. We welcome submissions of original research or review articles on, but not limited to, the following topics:
- Immune, stromal, and hematopoietic malignant cellular interactions.
- Molecules within the bone marrow microenvironment.
- Oncogenic pathways in bone marrow driving blood cancer progress.
- Biotechnology, therapeutic tools, or biomaterials to model or target the blood cancer microenvironment.
Dr. Jehan J. El-Jawhari
Guest Editor
Manuscript Submission Information
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Keywords
- blood cancers
- bone marrow
- microenvironment
- immune stromal interactions
- mesenchymal stem cells
