Advances in Targeted Therapy of Neuroblastoma

A special issue of Biomedicines (ISSN 2227-9059). This special issue belongs to the section "Neurobiology and Clinical Neuroscience".

Deadline for manuscript submissions: 30 June 2024 | Viewed by 133

Special Issue Editor


E-Mail Website
Guest Editor
1. Graduate Institute of Biomedical Sciences, China Medical University, Taichung 110122, Taiwan
2. Research Center for Cancer Biology, China Medical University, Taichung 110122, Taiwan
3. Institute of Biochemistry and Molecular Biology, College of Life Sciences, China Medical University, Taichung 110122, Taiwan
Interests: cancer targeted therapy; cancer immunotherapy; post-translational modifications; chromatin remodeling

Special Issue Information

Dear Colleagues,

Neuroblastoma is the most common extracranial solid tumor of childhood. Over the past few decades, the advances in targeted therapy of neuroblastoma have greatly improved patient survival outcomes, such as ALK inhibitors, RAS-MAPK inhibitors, targeting MYCN through AURORA and BET inhibitors, epigenetic therapies, and GD2-based immunotherapy. However, many patients still develop relapsed and refractory disease. Recent progress in the developmental origin and phenotypic plasticity of neuroblastoma has provided new insights into the pathogenesis of neuroblastoma. This knowledge, along with the cutting-edge single-cell applications of next-generation sequencing technologies, will inform a further delineation of the molecular basis of neuroblastoma, as well as the development of novel biomarkers and therapies for precision medicine strategies. 

Dr. Xing-Guo Li
Guest Editor

Manuscript Submission Information

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Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2600 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • neuroblastoma
  • targeted therapy
  • single-cell NGS technologies
  • epigenetic therapy
  • immunotherapy

Published Papers

This special issue is now open for submission.
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