Ovarian Cancer: From Mechanisms to Novel Target Therapies
A special issue of Biomedicines (ISSN 2227-9059). This special issue belongs to the section "Molecular and Translational Medicine".
Deadline for manuscript submissions: 31 May 2024 | Viewed by 101
Special Issue Editor
Special Issue Information
Dear Colleagues,
Epithelial ovarian cancer (EOC) is the leading cause of gynecologic malignancy-related deaths worldwide. Despite advances in multidisciplinary treatment, the overall mortality has remained steady over the past thirty years. Most EOC patients are diagnosed at an advanced stage, and they eventually develop chemo-resistant relapsed disease despite surgery and combination chemotherapy. To date, the mechanism underlying chemo-resistance in ovarian cancer remains unclear. In addition, ovarian cancer falls under a heterogeneous group of malignancies that arise from various cell types, and the genetic mechanisms involved in chemo-resistance should be complex and differentially defined among different subtypes of ovarian cancer. Thus, to develop novel therapeutic strategies, it is crucial to define reliable predictive biomarkers for different subtypes and therapeutic resistance.
Dr. Yi-Hui Wu
Guest Editor
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Keywords
- epithelial ovarian cancer
- relapsed disease
- subtypes
- therapeutic resistance
- metastasis
