Dear Colleagues,

Biomechanical factors are crucial and may influence the processes of tissue growth, development, maintenance, degeneration, and repair. On the other hand, regenerative medicine where recent advances in tissue engineering have promoted the development of scaffolds that may be implanted in combination with cell-based therapies has brought us new therapeutic perspectives and opportunities. These regenerative strategies to restore damaged or diseased tissues have recently introduced advances in understanding of how cells and tissues adapt to the surrounding mechanical environment and forces. Biomechanics knowledge is, without any doubt, fundamental to the development of cell-based and medical devices and innovative clinical therapies, always considering the principles of tissue engineering and regenerative medicine for musculoskeletal, neural, cardiovascular, craniofacial, skin, urinary, and other tissues. Additionally, associated with innovative therapies, and due to the importance of biomechanical forces, rehabilitation and exercise protocol and physiotherapy are crucial in the total functional recovery of the patients.

In this Special Issue, contributors are encouraged to address two main aspects related to rehabilitation engineering. The first is regenerative medicine, cell-based therapies, and new medical devices for the regeneration and functional recovery of the tissues, where biomechanical aspects are crucial. The second is the estimation of biomechanical load applied to biological structures that could be accomplished by in vivo experimental methodologies and using in silico biomechanics modeling and simulation. This Special issue also welcomes original research papers, opinion papers or reviews where biomechanics methodologies are applied regarding the performance optimization of movement, factors determining biological tissues, injury prevention and rehabilitation, exercise protocols, and physiotherapy that are involved in the regeneration of tissues in vivo, but also validations in vitro and using animal models in preclinical trials and biomechanical modeling and simulation.

You may choose our Joint Special Issue in Applied Sciences.

Prof. Dr. Antonio P. Veloso
Dr. Ana Colette Maurício
Guest Editors

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• biomechanics
• regenerative medicine
• cell-based therapies
• medical devices
• exercise
• physiotherapy protocols
• functional evaluation
• histology
• biomaterials