The Cellular and Molecular Bases of Circadian Clocks
A special issue of Biology (ISSN 2079-7737). This special issue belongs to the section "Cell Biology".
Deadline for manuscript submissions: closed (31 July 2023) | Viewed by 5931
Special Issue Editor
Special Issue Information
Dear Colleagues,
It is presumed that ancient biological clocks originally evolved in unicellular organisms to coordinate cellular metabolism as per environmental demands. In order to anticipate and respond to daily geophysical variabilities, species of many phyla, including metazoans, have evolved an endogenous “timing” device, i.e., the circadian clock. The mammalian “clock” system is a hierarchical network of biological oscillators that ensures the temporal control of physiology. Recent studies have started revealing the molecular links which could connect the clock system with different pathologies. However, our grasp of clock-controlled tissue-specific gene expression, and how it contributes to homeostasis at both the cellular and organismal levels, is still rudimentary. These investigations are essential to not only reveal the molecular mechanisms through which an “altered/broken” clock could possibly lead to the development of chronic disease, but also their therapeutic targeting.
This Special Issue focuses on “The Cellular and Molecular Bases of Circadian Clocks”. The main objectives are to understand the mechanistic basis of clock functioning in health and disease.
This Special Issue welcomes the submission of original research and review articles focusing on the cellular and molecular aspects of the circadian clock, in addition to its relationship with pathologies and their therapeutic targeting. This Special Issue will enlighten readers about new discoveries, advances, and developments in the field of chronobiology.
Dr. Atish Mukherji
Guest Editor
Manuscript Submission Information
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