Application of Bioengineering to Orthopedics

A special issue of Bioengineering (ISSN 2306-5354). This special issue belongs to the section "Regenerative Engineering".

Deadline for manuscript submissions: 31 October 2024 | Viewed by 778

Special Issue Editor


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Guest Editor
Chicago Department of Orthopedics, University of Illinois, Chicago, IL, USA
Interests: orthopaedics; biomechanics; smart medical devices

Special Issue Information

Dear Colleagues,

We are excited to announce the launch of our Special Issue titled "Application of Bioengineering to Orthopedics." This issue explores the interdisciplinary field where bio-engineering and orthopedics intersect, highlighting innovative solutions and recent advancements that have significantly impacted orthopedic clinical practice and patient outcomes.

This Special Issue will cover various topics, including tissue engineering, biomaterials, 3D bioprinting, the use of artificial intelligence in orthopedic surgery and rehabilitation, biomechanical studies, and the application of augmented reality to surgery pre-planning in orthopedics. Our goal is to showcase the latest research and developments in this dynamic field, providing valuable insights and knowledge to both researchers and practitioners.

We can gain valuable insights into the mechanics of various joints and their associated pathologies, ligaments, and tendon studies through detailed biomechanical analysis. This issue will also include nanotechnologies and explore how these cutting-edge techniques revolutionize our understanding of orthopedic prosthesis design and patient-specific implants. One example of the application of bio-engineering to orthopedics is the creation of coated surfaces on implants that prevent bacterial survival.

Moreover, we will explore the application of 3D printing technology in creating customized devices and implants tailored to individual patient needs. Finite Element Analysis (FEA) and motion analysis will be highlighted as essential tools in evaluating the performance and suitability of these devices in a simulated environment prior to clinical application.

Simulation studies are invaluable in understanding the behavior of implants and biological tissues under various conditions. We will discuss using cadaveric or animal tissue models and sawbones models of multiple joints to simulate pathologies and analyze the resulting changes in joint motion, stress, strain, and moment arms.

This Special Issue will also cover various subspecialties within orthopedics, including adult hip and knee reconstruction, meniscus, ACL (Anterior Cruciate Ligament), PCL (Posterior Cruciate Ligament) studies, and implant studies, as well as the use of artificial intelligence in orthopedic surgery and rehabilitation. By integrating bioengineering principles with orthopedic knowledge, we can develop innovative solutions and improve patient outcomes and longevity.

Through this Special Issue, we aim to highlight the symbiotic relationship between bioengineering and orthopedics and how their convergence pushes the boundaries of what is possible regarding the treatment and understanding of orthopedic conditions. We invite researchers, clinicians, and academicians to contribute their valuable insights and discoveries to this exciting and evolving field. We encourage authors to contribute original research articles, review articles, and case studies on how bioengineering has enhanced and transformed orthopedics. Join us in exploring the intersection of bio-engineering and clinical orthopedics, where innovation meets real solutions for current and future patient care.

Dr. Farid Amirouche
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Bioengineering is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2700 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Published Papers (1 paper)

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Research

12 pages, 2069 KiB  
Article
Surface Modification of Polyetheretherketone (PEEK) Intervertebral Fusion Implant Using Polydopamine Coating for Improved Bioactivity
by Suzy Park and Tae-Gon Jung
Bioengineering 2024, 11(4), 343; https://doi.org/10.3390/bioengineering11040343 - 31 Mar 2024
Viewed by 569
Abstract
The occurrence of bone diseases has been increasing rapidly, in line with the aging population. A representative spinal fusion material, polyetheretherketone (PEEK), is advantageous in this regard as it can work in close proximity to the elastic modulus of cancellous bone. However, if [...] Read more.
The occurrence of bone diseases has been increasing rapidly, in line with the aging population. A representative spinal fusion material, polyetheretherketone (PEEK), is advantageous in this regard as it can work in close proximity to the elastic modulus of cancellous bone. However, if it is used without surface modification, the initial osseointegration will be low due to lack of bioactivity, resulting in limitations in surgical treatment. In this study, we aimed to modify the surface of PEEK cages to a hydrophilic surface by coating with polyethylene glycol (PEG), hyaluronic acid (HA), and polydopamine (PDA), and to analyze whether the coated surface exhibits improved bioactivity and changes in mechanical properties for orthopedic applications. Material properties of coated samples were characterized and compared with various PEEK groups, including PEEK, PEEK-PEG, PEEK-HA, and PEEK-PDA. In an in vitro study, cell proliferation was found to be enhanced on PDA-coated PEEK; it was approximately twice as high compared to the control group. In addition, mechanical properties, including static and torsion, were not affected by the presence of the coating. Thus, the results suggest that PEEK-PDA may have the potential for clinical application in fusion surgery for spinal diseases, as it may improve the rate of osseointegration. Full article
(This article belongs to the Special Issue Application of Bioengineering to Orthopedics)
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