Diagnostic Biomedical Image and Processing with Artificial Intelligence and Deep Learning

A special issue of Bioengineering (ISSN 2306-5354). This special issue belongs to the section "Biosignal Processing".

Deadline for manuscript submissions: 31 August 2024 | Viewed by 1169

Special Issue Editors


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Guest Editor
Digital Medical Research Centre, Fudan University, Shanghai 200438, China
Interests: medical image processing; image-guided intervention; application of virtual and augmented reality technologies in medicine

E-Mail Website
Guest Editor
Digital Medical Research Centre, Fudan University, Shanghai 200438, China
Interests: artificial intelligence; medical image processing techniques; 3D computer vision; surgical navigation; computer-assisted surgical technologies such as surgical robots

E-Mail Website
Guest Editor
Digital Medical Research Centre, Fudan University, Shanghai 200438, China
Interests: artificial intelligence analysis of medical images; biophysical modeling

Special Issue Information

Dear Colleagues,

As technology continues to evolve, biomedical imaging, including radiographic images (CT, MRI, PET, SPECT, etc.), pathological images, ophthalmic images (Optical Coherence Tomography - OCT, OCT Angiography - OCTA, fundus photography, and fluorescein angiography), microscopy imaging, protein images, and other related biomedical images, are playing an increasingly important role in assisting clinical disease diagnosis, treatment decisions, and scientific research. With the continuous enrichment of large-scale image datasets and the ongoing advancement of cutting-edge parallel graphics processing units, advanced image processing techniques, particularly the integration of biomedical imaging and AI, hold the potential to further enhance diagnostic efficiency and accuracy. This progress is expected to significantly advance scientific research in the field of biomedical imaging.

Advanced image processing techniques, particularly AI-based methods represented by deep learning, have been widely applied to various tasks in biomedical images. These tasks range from image classification, image segmentation, image reconstruction, image super-resolution, image registration, and image fusion to disease classification, lesion detection, and survival prediction. However, the challenges of AI in biomedical image analysis still require further resolution.

We are pleased to invite you as contributors of this Special Issue to publish your experimental and theoretical results of new approaches and applications in biomedical imaging. This Special Issue aims to focus on articles and cutting-edge technology reviews that apply the most advanced techniques to

biomedical image processing and applications. The topics include constructing data-efficient deep learning models to address the demands of large datasets, establishing models with efficient data annotation, enhancing algorithm robustness and interpretability to create high-confidence models, and developing more efficient and advanced algorithms for specific tasks.

In this Special Issue, original research articles and reviews are welcome. Research areas may include (but not limited to) the following:

  1. Advanced image processing techniques applied to biomedical imaging:

Image segmentation, image reconstruction, image super-resolution, image registration, image fusion.

  1. Advanced application technologies based on biomedical imaging:

Image and disease classification, object and lesion detection, organ region and marker localization, organ and structure segmentation, survival prediction, radiation therapy planning, assistive treatment, surgical navigation, innovative approaches in large model techniques, fusion of biomedical imaging and multimodal information.

  1. Data-efficient models based on biomedical imaging:

Training methods based on limited annotated data (unsupervised learning, semi-supervised learning, self-supervised learning, and weakly supervised learning), efficient domain adaptation models and approaches, efficient data annotation models and approaches.

  1. Applications of novel imaging and imaging techniques in biomedical and engineering fields:

Cutting-edge imaging techniques such as super-resolution imaging, fast image reconstruction and imaging techniques, emerging radiographic imaging, latest imaging techniques for pathological images, microscopic images, and the integration of virtual reality and augmented reality technologies with ai in biomedical imaging. Also, applications in the biomedical field utilizing novel imaging combined with AI, including the use of protein imaging and digital signal images.

  1. Other relevant technical articles and state-of-the-art technology reviews in the field.

We look forward to receiving your contributions.

Prof. Dr. Zhijian Song
Prof. Dr. Manning Wang
Dr. Shuo Wang
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Bioengineering is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2700 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • biomedical image
  • artificial intelligence
  • deep learning
  • image processing
  • medical imaging
  • computer-assisted diagnosis
  • pattern recognition
  • computer vision
  • bioengineering

Published Papers (2 papers)

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Research

13 pages, 2034 KiB  
Article
An Automated Video Analysis System for Retrospective Assessment and Real-Time Monitoring of Endoscopic Procedures (with Video)
by Yan Zhu, Ling Du, Pei-Yao Fu, Zi-Han Geng, Dan-Feng Zhang, Wei-Feng Chen, Quan-Lin Li and Ping-Hong Zhou
Bioengineering 2024, 11(5), 445; https://doi.org/10.3390/bioengineering11050445 - 30 Apr 2024
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Abstract
Background and Aims: Accurate recognition of endoscopic instruments facilitates quantitative evaluation and quality control of endoscopic procedures. However, no relevant research has been reported. In this study, we aimed to develop a computer-assisted system, EndoAdd, for automated endoscopic surgical video analysis based on [...] Read more.
Background and Aims: Accurate recognition of endoscopic instruments facilitates quantitative evaluation and quality control of endoscopic procedures. However, no relevant research has been reported. In this study, we aimed to develop a computer-assisted system, EndoAdd, for automated endoscopic surgical video analysis based on our dataset of endoscopic instrument images. Methods: Large training and validation datasets containing 45,143 images of 10 different endoscopic instruments and a test dataset of 18,375 images collected from several medical centers were used in this research. Annotated image frames were used to train the state-of-the-art object detection model, YOLO-v5, to identify the instruments. Based on the frame-level prediction results, we further developed a hidden Markov model to perform video analysis and generate heatmaps to summarize the videos. Results: EndoAdd achieved high accuracy (>97%) on the test dataset for all 10 endoscopic instrument types. The mean average accuracy, precision, recall, and F1-score were 99.1%, 92.0%, 88.8%, and 89.3%, respectively. The area under the curve values exceeded 0.94 for all instrument types. Heatmaps of endoscopic procedures were generated for both retrospective and real-time analyses. Conclusions: We successfully developed an automated endoscopic video analysis system, EndoAdd, which supports retrospective assessment and real-time monitoring. It can be used for data analysis and quality control of endoscopic procedures in clinical practice. Full article
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18 pages, 1620 KiB  
Article
Reference Data for Diagnosis of Spondylolisthesis and Disc Space Narrowing Based on NHANES-II X-rays
by John Hipp, Trevor Grieco, Patrick Newman, Vikas Patel and Charles Reitman
Bioengineering 2024, 11(4), 360; https://doi.org/10.3390/bioengineering11040360 - 08 Apr 2024
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Abstract
Robust reference data, representing a large and diverse population, are needed to objectively classify measurements of spondylolisthesis and disc space narrowing as normal or abnormal. The reference data should be open access to drive standardization across technology developers. The large collection of radiographs [...] Read more.
Robust reference data, representing a large and diverse population, are needed to objectively classify measurements of spondylolisthesis and disc space narrowing as normal or abnormal. The reference data should be open access to drive standardization across technology developers. The large collection of radiographs from the 2nd National Health and Nutrition Examination Survey was used to establish reference data. A pipeline of neural networks and coded logic was used to place landmarks on the corners of all vertebrae, and these landmarks were used to calculate multiple disc space metrics. Descriptive statistics for nine SPO and disc metrics were tabulated and used to identify normal discs, and data for only the normal discs were used to arrive at reference data. A spondylolisthesis index was developed that accounts for important variables. These reference data facilitate simplified and standardized reporting of multiple intervertebral disc metrics. Full article
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