Engineering Biomaterials for Regenerative Medicine Applications

Dear Colleagues,

There is emerging interest in the innovation of biomaterials used in medical applications designed to interact with various biological systems. They are used in various applications, including implants, drug delivery systems, therapeutic models, and tissue engineering scaffolds. Biomaterials are used in regenerative medicine to create scaffolds that provide a temporary structure for cells to grow and develop into new tissue regeneration. The scaffold can be made from various materials, including natural polymers, synthetic polymers, and other material platforms. The choice of material depends on the specific application. For example, natural polymers, such as collagen, chitosan, cellulose, gelatin, alginate, silk fibroin, and starch, alone or in combination, are widely used to create scaffolds for soft tissue engineering applications. Synthetic polymers, such as polylactic acid (PLA), Polylactic-co-glycolic acid (PLGA), and polyglycolic acid (PGA), are often used to create scaffolds for hard tissue engineering applications. Metal nanostructures, such as iron, gold, zinc, etc., often create scaffolds for bone tissue engineering applications. In addition, biomaterials can be used to improve the success of regenerative medicine therapies in several ways. They can provide a temporary structure for cells to grow and develop, deliver cells to the target site, and provide a controlled release of growth factors and other signaling molecules. Biomaterials are an important part of the future of regenerative medicine applications. As the field continues to develop, biomaterials will play an increasingly important role in developing innovative therapies for various diseases and conditions.

Here are some topics of interest that this Special Issue is focusing on:

• Artificial skin: Papers report the biomaterials used to create artificial skin that can be used to treat burns and other skin injuries.
• Artificial cartilage: Papers report the biomaterial used to create artificial cartilage that can replace damaged cartilage in the knee, hip, and other joints.
• Artificial bone: Papers report the biomaterial used to create artificial bone that can replace damaged bone in the spine, skull, and other bones.
• Tissue engineering: Papers report the biomaterials used to create scaffolds that can be seeded with cells to grow new tissue. This is being used to develop new treatments for a variety of conditions, including heart disease, stroke, and spinal cord injury.
• Drug delivery: Papers on the interest in biomaterials use in drug delivery to tumors in a controlled and targeted manner.
• Immunotherapy: Papers focus on biomaterials that can deliver immune cells to tumors, which can help stimulate the body's immune system to fight cancer.
• Tissue engineering: Papers use biomaterials to create scaffolds that can be seeded with cells to grow new tissue to replace damaged tissue caused by cancer.
• Diagnostics: Biomaterials applications to develop new diagnostic tools that can help identify cancer early when it is most treatable.

In the future, biomaterials will be a promising new frontier in regenerative medicine. As the field continues to develop, biomaterials will play an increasingly important role in developing new therapies for various diseases and injuries. As the field of regenerative medicine continues to evolve, biomaterials will play an increasingly important role in the development of new treatments.

Dr. Ramar Thangam
Dr. Heemin Kang
Dr. Venugopal Krishnan
Guest Editors

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• biomaterials
• tissue repair
• regenerative medicine
• stem cells
• immune cells
• cancer therapy
• biomedical devices and implants
• tissue regeneration