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Applied Sciences
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Food-Related Bioactive Compounds: Extraction, Bioavailability, and Applications Volume II
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Food-Related Bioactive Compounds: Extraction, Bioavailability, and Applications Volume II

A special issue of Applied Sciences (ISSN 2076-3417). This special issue belongs to the section "Chemical and Molecular Sciences".

Deadline for manuscript submissions: 30 June 2024 | Viewed by 3539

Special Issue Editors

Dr. Ivelina Desseva

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Guest Editor
Department of Analytical Chemistry and Physical Chemistry, Technological Faculty, University of Food Technologies, 4002 Plovdiv, Bulgaria
Interests: food chemistry; food analysis; biological activity; antioxidants; analytical methods; bioaccessibility; bioavailability; simulated food digestion methods; bioactive peptides
Special Issues, Collections and Topics in MDPI journals
Dr. Dasha Mihaylova

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Guest Editor
Department of Biotechnology, University of Food Technologies, 4002 Plovdiv, Bulgaria
Interests: biological activity; antioxidants; analytical methods; phytochemistry; bioaccessibility; food chemistry; fruit quality
Special Issues, Collections and Topics in MDPI journals

Special Issue Information

Dear Colleagues,

This Special Issue is the continuation of our previous Special Issue, titled "Food-Related Bioactive Compounds: Extraction, Bioavailability, and Applications".

The food we consume was never as much in focus as it is today. More and more people pay attention to their diet and demand added value to the products they use. The so-called bioactive compounds include diverse groups of molecules that may influence the human body’s functions. While most of the scientific community is focused on health-promoting compounds, we should keep in mind that there are others that may harm. This is why high-quality research on food-related bioactive compounds is very much needed. Plant, animal and marine samples are the traditionally studied sources. Additionally, with the entry of edible insects, research on their health effects is also perspective. However, this is only one piece of the big picture. The next step is to evaluate the influence of gastrointestinal digestion. Although a complex process, it is worth going deeper in that direction. Undoubtedly, many data have been published so far, but fortunately, there is still room for updating. In this regard, this Special Issue will gather original research papers or state-of-the-art reviews on the advances in the extraction of any valuable compounds, from traditional or alternative sources, with potential food applications. Highlights on the bioavailability and further applications are also welcomed.  

Dr. Ivelina Desseva
Dr. Dasha Mihaylova
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Applied Sciences is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2400 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • food bioactive compounds
  • biological activity
  • extraction
  • bioaccessibility and bioavailability
  • antioxidants, and antimicrobials
  • plant, animal, marine, and insect sources
  • health effects

Related Special Issue

Published Papers (3 papers)

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Research

14 pages, 1591 KiB  
Article
Assessment of Bioavailability Parameters of Mono- and Bistriazole Derivatives of Propynoylbetulin
by Monika Kadela-Tomanek, Arkadiusz Sokal, Klaudia Stocerz, Ewa Bębenek, Elwira Chrobak and Paweł Olczyk
Appl. Sci. 2024, 14(5), 1695; https://doi.org/10.3390/app14051695 - 20 Feb 2024
Viewed by 393
Abstract
Bioavailability describes the properties that determine the passage of a compound through biological barriers. In many cases, bioavailability depends on the lipophilicity of the compound. In this study, the lipophilicity as well as other bioavailability properties of the mono- and bistriazole derivatives of [...] Read more.
Bioavailability describes the properties that determine the passage of a compound through biological barriers. In many cases, bioavailability depends on the lipophilicity of the compound. In this study, the lipophilicity as well as other bioavailability properties of the mono- and bistriazole derivatives of betulin are presented. The lipophilicity was determined using RP-TLC and theoretical methods. The experimental lipophilicity of mono- and bistriazole derivatives is in the range from 4.39 to 7.85 and from 3.75 to 8.83, respectively. The lipophilicity of mono- and bistriazoles is similar, and the logPTLC depends on the type of substituent at the triazole ring. The introduction of a substituent with oxygen and nitrogen atoms decreases lipophilicity. Comparing the experimental and theoretical lipophilicity shows that the milogP and XLOGP3 programs best reproduce the experimental values. The in silico-determined pharmacokinetic parameters show that monotriazole derivatives could be used as oral drugs while bistriazoles show low availability after oral administration. Triazoles could be used as transdermal drugs. The analysis of in silico bioavailability parameters shows that the type of substituent at the triazole ring influences the pharmacokinetic properties, while the number of triazole rings slightly affects the bioavailability properties of the compound. Full article
(This article belongs to the Special Issue Food-Related Bioactive Compounds: Extraction, Bioavailability, and Applications Volume II)
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23 pages, 1054 KiB  
Article
Aromatized Wine-Type Beverages with Added Byproducts of Essential Rose Oil Industry
by Anton Slavov, Hristo Spasov, Rada Dinkova, Petko Denev, Ivayla Dincheva, Mariyana Georgieva Topuzova and Vesela Chalova
Appl. Sci. 2023, 13(18), 10417; https://doi.org/10.3390/app131810417 - 18 Sep 2023
Viewed by 714
Abstract
The aroma bouquet of wine depends mainly on grape (variety, crop, climate, location, and so on), yeasts/microorganisms, and wine aging. Additionally, the wine flavor can be modulated by adding herbs, extracts, byproducts, and so on. The aim of the present study was to [...] Read more.
The aroma bouquet of wine depends mainly on grape (variety, crop, climate, location, and so on), yeasts/microorganisms, and wine aging. Additionally, the wine flavor can be modulated by adding herbs, extracts, byproducts, and so on. The aim of the present study was to characterize aromatized wine-type beverages (AWTBs) prepared by supplementation with rose oil industry byproducts (ROIBs). Three approaches were employed: 1. dried ROIBs were added to the grape must, followed by fermentation with Saccharomyces cerevisiae (ARW_CoF); 2. dried ROIBs were added to preliminarily prepared rosé (ARW_M); 3. 70% (v/v) ethanolic extracts of ROIBs were added to preliminarily prepared rosé (ARW_E). The polyphenol content in the modified beverages increased significantly from 230.00 ± 5.21 (control) to 296.13 ± 3.57 (ARW_M_100), 295.50 ± 3.78 (ARW_CoF_100), and 293.73 ± 4.29 (ARW_E_400) µmol GAE/L. The addition of ROIBs did not alter the formation of higher alcohols, since their contents in the AWTBs and the control were below 65 mg/L. The amount of phenethyl alcohol increased significantly from 1.07 ± 0.15 mg/L to 4.08 ± 0.30, 4.96 ± 0.24, and 5.77 ± 0.28 mg/L in the ARW_E_400, ARW_M_100, and ARW_CoF_100, respectively. The sensory evaluation revealed a preference for AWTBs from the ARW_CoF series. The results suggested that rose byproducts could be successfully utilized for the preparation of new AWTBs enriched with phenolic antioxidants, while exhibiting a distinctive and pleasant rose aroma. Full article
(This article belongs to the Special Issue Food-Related Bioactive Compounds: Extraction, Bioavailability, and Applications Volume II)
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10 pages, 4647 KiB  
Communication
PepLab Platform: Database and Software Tools for Analysis of Food-Derived Bioactive Peptides
by Zhelyazko Terziyski, Margarita Terziyska, Ivelina Deseva, Stanka Hadzhikoleva, Albert Krastanov, Dasha Mihaylova and Emil Hadzhikolev
Appl. Sci. 2023, 13(2), 961; https://doi.org/10.3390/app13020961 - 10 Jan 2023
Cited by 4 | Viewed by 1921
Abstract
Research on food-derived bioactive peptides is expanding and the need for a convenient online platform that combines a foolproof and intuitive user interface with a reliable database and tools for prediction and analysis is rising. In this regard, this paper presents an open-access [...] Read more.
Research on food-derived bioactive peptides is expanding and the need for a convenient online platform that combines a foolproof and intuitive user interface with a reliable database and tools for prediction and analysis is rising. In this regard, this paper presents an open-access web-based platform PepLab (Peptides Laboratory). The database contains 2764 peptide sequence entries, grouped into sixteen classes according to their biological activity and into seven classes according to the source from which they were derived. Moreover, it includes bioinformatic tools for their processing and analysis. The DMpep tool allows extracting information about a number of physicochemical characteristics of a peptide or a set of peptides, including those that are not recorded in the database. The main advantages of PepLab are a user-friendly interface, a responsive design, and optimized search engines for better visibility on the Internet. Prediction of non-reported activity is available based on amino acid sequence analysis. In addition, users can download data and results in a convenient format (text and/or graphic) that was limited in the existing platforms. In this way, the presented PepLab platform will be helpful for researchers from various fields—bioinformatics, pharmaceuticals, food sciences, dietetics, biotechnology, analytical chemistry, etc. Full article
(This article belongs to the Special Issue Food-Related Bioactive Compounds: Extraction, Bioavailability, and Applications Volume II)
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