Search for Articles:
Title / Keyword
Author / Affiliation / Email
Journal
Article Type
 
 
Advanced Search
 
Section
Special Issue
Volume
Issue
Number
Page
 
4.5
2.7
Journals
Applied Sciences
Special Issues
Polymer Surface Treatments for Drug Delivery and Wound Healing
share announcement

Polymer Surface Treatments for Drug Delivery and Wound Healing

A special issue of Applied Sciences (ISSN 2076-3417). This special issue belongs to the section "Materials Science and Engineering".

Deadline for manuscript submissions: 20 May 2024 | Viewed by 1984

Special Issue Editor

Dr. Van-An Duong

E-Mail
Guest Editor
The Institute of Molecular Medicine, The University of Texas Health Science Center at Houston, Houston, TX 77030, USA
Interests: drug delivery; lipid nanoparticles; bioavailability; DSC; FTIR; dissolution; solubility; HPLC; separation; pharmaceutical analysis; LC–MS; proteomics; proteome
Special Issues, Collections and Topics in MDPI journals

Special Issue Information

Dear Colleagues,

In recent decades, various nanocarriers have been developed for drug delivery and wound healing, including polymeric, lipid, and inorganic nanoparticles. Notably, the surfaces of these nanocarriers can be modified with polymers to enhance drug solubility, absorption, bioavailability, and overall therapeutic effects in drug delivery as well as wound healing efficacy. Surface modification can alter the surface charge, improve mucoadhesion and drug absorption, and enable targeted drug delivery of nanocarriers. 

Polymer surface treatments of nanocarriers are being investigated for drug delivery and wound healing. These studies will pave the way for the success of other nanocarriers.

In this Special Issue, we welcome original research articles and reviews on topics including, but not limited to, the following:

  • Development of polymer-based surface-modified drug delivery systems for different purposes;
  • Applications of polymer surface treatment for wound healing;
  • Improvement of nanocarrier properties using polymer surface treatment;
  • Comprehensive reviews of polymer surface treatments for drug delivery and wound healing.

Dr. Van-An Duong
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Applied Sciences is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2400 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • polymer
  • surface modification
  • nanocarriers
  • lipid nanoparticles
  • wound healing
  • drug delivery
  • targeting
  • inorganic nanoparticles
  • bioavailability

Published Papers (2 papers)

Download All Papers
Order results
Result details
Show export options expand_more Show export options expand_less
Select all
Export citation of selected articles as:

Editorial

Jump to: Research

3 pages, 199 KiB  
Editorial
Polymer Surface Treatments for Drug Delivery and Wound Healing
by Van-An Duong
Appl. Sci. 2023, 13(16), 9054; https://doi.org/10.3390/app13169054 - 08 Aug 2023
Cited by 1 | Viewed by 642
Abstract
Nanomedicine is a cutting-edge field at the intersection of nanotechnology and medicine that has experienced significant advancements in recent decades [...] Full article
(This article belongs to the Special Issue Polymer Surface Treatments for Drug Delivery and Wound Healing)

Research

Jump to: Editorial

21 pages, 4910 KiB  
Article
Formulation by Design of an Innovative Tea Tree Oil Nanoemulgel Incorporating Mupirocin for Enhanced Wound Healing Activity
by Mahdi M. Bujubarah, Heba S. Elsewedy, Tamer M. Shehata and Wafaa E. Soliman
Appl. Sci. 2023, 13(24), 13244; https://doi.org/10.3390/app132413244 - 14 Dec 2023
Viewed by 1017
Abstract
Mupirocin is an antibacterial agent that has been documented to be effective in treating superficial skin infections. However, the main limitation of its application is bacterial resistance. Therefore, there is a need to determine a way to potentiate its efficiency. Accordingly, this obstacle [...] Read more.
Mupirocin is an antibacterial agent that has been documented to be effective in treating superficial skin infections. However, the main limitation of its application is bacterial resistance. Therefore, there is a need to determine a way to potentiate its efficiency. Accordingly, this obstacle led to this current investigation, which aims to find a way to improve the therapeutic action of mupirocin. This study focuses on the integration of tea tree oil with mupirocin to improve its antibacterial and wound healing capacities. Distinct nanoemulsions (NEs) were developed and the best of them were optimized using a central composite design (CCD) approach. The optimized NEs were mixed with a gel base to form a mupirocin-loaded nanoemulgel (NEG). The formulation was evaluated for characteristics including pH, viscosity, spreadability, and in vitro release over 6 h. The NEG was examined for its stability in two different conditions, namely at room temperature and refrigerated, for 3 months. Eventually, the NEG was inspected to determine its antibacterial and wound healing efficiencies. The developed mupirocin-loaded NEG exhibited good physical properties in terms of pH (6.13), viscosity (19,990 cP), spreadability (48.8 mm), and in vitro release over 6 h (51.4%). Moreover, it showed good stability with no significant difference in the evaluated parameters when stored for 3 months in the two conditions. Ultimately, mupirocin-loaded NEG prepared with tea tree oil exhibited a significant antibacterial influence in addition to good healing efficiency. Full article
(This article belongs to the Special Issue Polymer Surface Treatments for Drug Delivery and Wound Healing)
►▼ Show Figures

Figure 1

Show export options expand_more Show export options expand_less
Select all
Export citation of selected articles as:
 
Displaying articles 1-2
Back to TopTop