Biological Efficacy of Plant Extracts: Latest Advances and Prospects

A special issue of Applied Sciences (ISSN 2076-3417). This special issue belongs to the section "Applied Biosciences and Bioengineering".

Deadline for manuscript submissions: closed (20 January 2023) | Viewed by 2502

Special Issue Editors


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Department of Biotechnology and Pharmaceutical Technology, Yuanpei University of Medical Technology, Hsinchu City 300, Taiwan
Interests: physiological activities and applications of tea and plant polyphenols; refined and stabilized fish oil and polyunsaturated fatty acids; antioxidant, anti-inflammatory, antibacterial, anticancer, skin care and other functional testing of natural products and microbial fermentation products; microencapsulation engineering and production and release of biologically active substances; biotechnology health product design and development; food safety and health management
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Guest Editor
Division of Nephrology, Department of Internal Medicine, Taoyuan Branch of Taipei Veterans General Hospital, Taoyuan 330, Taiwan
Interests: translational medicine in chronic kidney disease, mineral and bone disorders; uremic toxins and vascular calcification; oxidant and inflammatory signaling transduction pathways; novel biomarkers and pharmaceutical targets in prediction models
Special Issues, Collections and Topics in MDPI journals

Special Issue Information

Dear Colleagues,

We welcome you to contribute to a Special Issue of Applied Sciences entitled “Biological Efficacy of Plant Extracts: Latest Advances and Prospects”. Plants containing abundant natural nutrients and bioactive phytochemicals serve as the main raw materials for effective nutraceuticals and pharmaceuticals. Thus, the importance of plant extracts cannot be overemphasized. One of the most famous and successful examples is phlorizin, a potent inhibitor of human sodium-glucose cotransporter (SGLT). It was originally isolated from the bark of apple trees. SGLT-2 inhibitors have been developed as a class of prescription medicines that are FDA-approved treatment for adults with type 2 diabetes. In light of this, natural products from plant extracts have the potential to become a new generation of bio-products suitable for use in medical applications. Myriad plant extracts have been well studied to date, but many others have not. To improve human health, there is also an urgent need to develop more novel and effective regimens.

This Special Issue aims to provide a comprehensive understanding of the latest discoveries for biological efficacy in plant extracts. We heartily invite authors to contribute original research articles and reviews that help to refresh therapeutic applications in the future.

Prof. Dr. Chih-Cheng Lin
Dr. Jia-Feng Chang
Guest Editors

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Keywords

  • plant extracts
  • phytochemicals
  • medicinal plants
  • biological activity
  • natural nutrients
  • nutraceuticals
  • pharmaceuticals
  • herbal medicine
  • ethnopharmacology

Published Papers (1 paper)

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Research

18 pages, 2205 KiB  
Article
An In Vitro Study of the Healing Potential of Black Mulberry (Morus nigra L.) Extract in a Liposomal Formulation
by Adriana Ramona Memete, Florina Miere (Groza), Vasile Laslo, Cornelia Purcarea, Laura Vicas, Mariana Ganea, Angela Antonescu and Simona Ioana Vicas
Appl. Sci. 2023, 13(2), 1041; https://doi.org/10.3390/app13021041 - 12 Jan 2023
Cited by 5 | Viewed by 1860
Abstract
Natural compounds are used in modern dermal treatments to avoid side effects commonly associated with conventional treatments. The aim of our study was to develop a liposomal formulation including black mulberry extract and to highlight its potential on the healing of normal human [...] Read more.
Natural compounds are used in modern dermal treatments to avoid side effects commonly associated with conventional treatments. The aim of our study was to develop a liposomal formulation including black mulberry extract and to highlight its potential on the healing of normal human dermal fibroblasts (NHDF) in vitro using the scratch test. Mulberry-loaded liposomes (MnL) were prepared using a thin-film hydration method based on cholesterol (C) and phosphatidylcholine (PC) in a 1:3 (w/w) ratio. The liposomal formulation was characterized by analyzing its size, electric surface potential, morphology, entrapment efficiency, and in vitro healing effects. Also, the black mulberry fruits (Morus nigra L.) were characterized from point of view of polyphenolic compounds and antioxidant capacity by Ferric-Reducing Antioxidant Power (FRAP) assay. HPLC-DAD-MS (ESI+) (high performance liquid chromatography-photodiode array detection-mass spectrometry (electrospray ionization)) analysis indicated the presence of phenolic compounds namely from hydroxybenzoic and hydroxycinnamic acids and flavonols. Among flavonols, quercetin-glucoside represented 50.56%, and chlorogenic acid was the predominant compound among hydroxycinnamic acids (37.06%). In vitro fibroblast wound closure was more effective with mulberry-loaded liposomes (MnL) than extracts of mulberries. According to our study, mulberry-loaded liposomes have been shown to be effective in wound healing and can be used as a natural treatment. Full article
(This article belongs to the Special Issue Biological Efficacy of Plant Extracts: Latest Advances and Prospects)
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