Advances in Magnetic Resonance Imaging (MRI)

A special issue of Applied Sciences (ISSN 2076-3417). This special issue belongs to the section "Biomedical Engineering".

Deadline for manuscript submissions: 20 July 2024 | Viewed by 792

Special Issue Editor


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Guest Editor
Department of Anatomy, Yonsei University Wonju College of Medicine, Wonju 26426, Republic of Korea
Interests: magnetic resonance imaging; medical imaging; diagnosis; radiology; 3-dimensional modeling; segmentation
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Special Issue Information

Dear Colleagues,

This Special Issue presents advances in magnetic resonance imaging for clinicians and researchers. Magnetic resonance imaging, along with related technologies, have been continuously improved to provide diagnostic accuracy and various medical applications. Recent advances, including 3-dimensional modeling and segmentation using artificial intelligence, will enhance the utility of magnetic resonance imaging in numerous fields. Interested radiologists, technicians, doctors, and researchers may contribute their novel techniques and findings to enrich their colleagues. Both hardware and software can be the focus for the papers, as long as it adds new knowledge to the field. This Special Issue might provide a forum for academic discussion among the peer researchers.

Dr. Beom Sun Chung
Guest Editor

Manuscript Submission Information

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Keywords

  • magnetic resonance imaging
  • medical imaging
  • diagnosis
  • radiology
  • 3-dimensional modeling
  • segmentation

Published Papers (1 paper)

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Research

11 pages, 2193 KiB  
Article
The Influence of Late Gadolinium Enhancement Cardiac Magnetic Resonance Image Analysis Imprecision on Myocardial Damage Quantification in Patients with Myocarditis: A Pilot Study
by Lana Kralj, Andreja Cerne Cercek, Alja Gomišček Novak and Borut Kirn
Appl. Sci. 2024, 14(1), 117; https://doi.org/10.3390/app14010117 - 22 Dec 2023
Viewed by 610
Abstract
Background: Myocardial damage in myocarditis is assessed through late gadolinium enhancement (LGE) cardiac magnetic resonance (CMR). Variability in quantifying myocarditis extent results from imprecise image segmentation and inconclusive data on quantification method selection. To improve analysis precision, segmentation steps are systematically ranked based [...] Read more.
Background: Myocardial damage in myocarditis is assessed through late gadolinium enhancement (LGE) cardiac magnetic resonance (CMR). Variability in quantifying myocarditis extent results from imprecise image segmentation and inconclusive data on quantification method selection. To improve analysis precision, segmentation steps are systematically ranked based on their inherent risks of error. Additionally, data on two distinct quantification methods are presented. Methods: Using newly developed software, four experts analyzed five LGE-CMR left ventricular (LV) short-axis (SAx) images of myocarditis patients in three sessions. Regions of interest (ROIs) (myocardial (ROImyoc), reference (ROIref), and exclusion region (ROIexcl)) were identified and used to calculate LGE extent with 3σ (intensity above three standard deviations (σ) in reference) and the full width at half maximum (FWHM) method (intensity above 50% of maximum signal in reference). The reference LGE extent was calculated and the influence of the ROIs on LGE extent variability was determined. Interobserver and intraobserver variability were evaluated as 1-intraclass correlation coefficient (ICC). Results: LGE extent variability was 6.2 ± 0.6% for 3σ and 4.0 ± 0.6% for FWHM. The contributions of ROImyoc, ROIref, and ROIexcl were 1.5 ± 0.2%, 2.7 ± 0.4%, and 2 ± 0.3%, respectively, for 3σ, and 1.1 ± 0.1%, 1.6 ± 0.4%, and 1.3 ± 0.3%, respectively, for FWHM. LGE extent was lower in FWHM. Interobserver variability was 0.56 for 3σ and 0.43 for FWHM. The intraobserver variability was higher for the 3σ method in all four observers. Conclusion: ROIref selection contributed most to LGE extent variability. FWHM yielded lower LGE extent and lower inter- and intraobserver variability. Due to low statistical significance, the findings are only partially confirmed. Full article
(This article belongs to the Special Issue Advances in Magnetic Resonance Imaging (MRI))
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