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Applied Sciences
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Advanced Dental Biomaterials: Technologies and Applications
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Advanced Dental Biomaterials: Technologies and Applications

A special issue of Applied Sciences (ISSN 2076-3417). This special issue belongs to the section "Applied Dentistry and Oral Sciences".

Deadline for manuscript submissions: 20 May 2024 | Viewed by 5398

Special Issue Editors

Dr. Anabela Baptista Pereira Paula

E-Mail Website
Guest Editor
Institute of Integrated Clinical Practice, Institute of Orthodontics, Laboratory of Evidence-based Science and Precision Dentistry, Faculty of Medicine, University of Coimbra, 3000-075 Coimbra, Portugal
Interests: dentistry; development of animal models for dental diseases (pulp capping, surgical models, gastric pathology); mechanical evaluation of composite resins; biomaterials (from molecular biology to cell biology); new approaches for dental pulp treatment (from drug development to in vivo experiments); research in medicine based on clinical practice evidence (systematic reviews and meta-analysis, and patient reported outcomes)
Special Issues, Collections and Topics in MDPI journals
Dr. Inês Francisco

E-Mail Website
Guest Editor
Institute of Orthodontics, Laboratory of Evidence-Based Science and Precision Dentistry, Institute for Clinical and Biomedical Research (iCBR), Area of Environment Genetics and Oncobiology (CIMAGO), Faculty of Medicine, University of Coimbra, 3000-075 Coimbra, Portugal
Interests: orthodontics; orthognathic surgery; SAOS; cleft palate; regenerative strategies; biomaterials; research in medicine based on clinical practice evidence (systematic reviews and meta-analysis, and patient reported outcomes)
Special Issues, Collections and Topics in MDPI journals

Special Issue Information

Dear Colleagues,

Therapy in the oro-dental and maxillo-facial region is challenging because the oral cavity has several tissues with distinct cell populations (ectodermal and mesodermal), making the procedures more complex. Dental materials must survive the harsh and fluctuating conditions of the mouth, and currently, no dental materials have the ideal properties for any dental applications. Therefore, new biomaterials have been developed for dental use which have a wider applicability in preventive, restorative, and regenerative treatments.

The aim of this Special Issue “Advanced Dental Biomaterials: Technologies and Applications” is to provide the latest information on dental biomaterials. Topics in this Special Issue include, but are not limited to: biocompatibility of biomaterials, nanorobots or dentirobots, mechanics characterization of dental biomaterials, regenerative strategies, dental composite materials, bonding adhesives, periodontal tissue engineering strategies, stem cells, pulp capping biomaterials, bone regeneration, cleft palate, surface modification techniques, titanium alloys, and 3D printing. High-quality research articles, clinical studies, review articles, and case reports are all welcome.

We invite you to submit your valuable contributions to this Special Issue.

Best regards,

Dr. Anabela Baptista Pereira Paula
Dr. Inês Francisco
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Applied Sciences is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2400 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • biomaterials
  • restorative dentistry
  • regenarative dentistry
  • orthodontics
  • orthognathic surgery
  • cleft palate
  • pulp regeneration
  • composite resins

Published Papers (4 papers)

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Research

12 pages, 1289 KiB  
Article
Evaluation of the Periotest Device as an Objective Measuring Tool for Tooth Mobility—A Clinical Evaluation Study
by Olga Gerasimidou, Timothy F. Watson and Brian J. Millar
Appl. Sci. 2024, 14(5), 1860; https://doi.org/10.3390/app14051860 - 23 Feb 2024
Viewed by 535
Abstract
Objective: The aim of this study was to allow researchers to evaluate the Periotest device as a reproducible tool that can be trusted to carry out accurately reproducible and comparable tooth mobility readings. Methods: A reproducibility test was initially conducted taking Periotest recordings [...] Read more.
Objective: The aim of this study was to allow researchers to evaluate the Periotest device as a reproducible tool that can be trusted to carry out accurately reproducible and comparable tooth mobility readings. Methods: A reproducibility test was initially conducted taking Periotest recordings for #16 every 10 min with 1 min intervals. Each time, three readings were recorded, and the average of the three was noted. This was followed by recordings for three different subject groups varying in age that were seen three times in 4 weeks, with 2-week intervals between each appointment; recordings were taken of #11, #13 and #16. Nonparametric analysis using the Wilcoxon signed-rank test was carried out. Results: For the reproducibility test, the values of all three readings for each recording session were either exactly the same or differed by up to ±2 Periotest value units. p-value results in the three patient groups showed no significant difference in Periotest values between appointments, with the minor exception of #16 in all three groups, but this was well within the limits of error of the device. Conclusions: Analysis of the Periotest readings in this study indicates that positive (higher) Periotest values correspond to increased tooth mobility. Full article
(This article belongs to the Special Issue Advanced Dental Biomaterials: Technologies and Applications)
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14 pages, 1001 KiB  
Article
Bone Mineral Density through DEXA and CBCT: A Systematic Review with Meta-Analysis
by Inês Francisco, Catarina Nunes, Flávia Pereira, Raquel Travassos, Madalena Prata Ribeiro, Filipa Marques, Mariana McEvoy, Mariana Santos, Catarina Oliveira, Carlos Miguel Marto, Francisco Caramelo, Anabela Baptista Paula and Francisco Vale
Appl. Sci. 2023, 13(10), 5962; https://doi.org/10.3390/app13105962 - 12 May 2023
Viewed by 1841
Abstract
Dual-energy X-ray absorptiometry is used to determine bone density in several pathologies, namely osteoporosis and fracture risk in post-menopausal women. The aim of this study was to identify, appraise and synthesize all available evidence about the correlation between Dual Energy X-ray Absorptiometry (DEXA) [...] Read more.
Dual-energy X-ray absorptiometry is used to determine bone density in several pathologies, namely osteoporosis and fracture risk in post-menopausal women. The aim of this study was to identify, appraise and synthesize all available evidence about the correlation between Dual Energy X-ray Absorptiometry (DEXA) and Cone Beam Computed Tomography (CBCT) techniques through a systematic review. A systematic literature search was conducted in the following databases: PubMed via MEDLINE, Cochrane Library, EMBASE and Web of Science Core Collection, along with several sources of grey literature. The Cochrane Risk of Bias Tools were used to perform the qualitative assessment of the selected studies. A total of 913 articles were initially scrutinized and 11 were included for qualitative analysis, of which 3 were included in a meta-analysis. Most of the included studies revealed a low risk of bias (7 out of 11). A strong correlation (min r = 0.46 max r = 0.62) between DEXA and CBCT values were found. Thus, opportunistic CBCT scans may be used to assess the bone mineral density and fracture risk, improving the ability to track disease progression and providing better care. Full article
(This article belongs to the Special Issue Advanced Dental Biomaterials: Technologies and Applications)
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11 pages, 1407 KiB  
Article
Three-Dimensional Pulp Volume Analysis in Lip and Palate Cleft Population
by Inês Francisco, Raquel Travassos, Filipa Marques, Madalena Prata Ribeiro, Mariana Rodrigues, Patrícia Quaresma, Francisco Caramelo, Carlos Miguel Marto, Anabela Baptista Paula, Catarina Nunes and Francisco Vale
Appl. Sci. 2023, 13(6), 3728; https://doi.org/10.3390/app13063728 - 15 Mar 2023
Viewed by 1084
Abstract
Aim: Cleft lip and palate (CLP) patients have a greater predisposition to tooth malformation, which could affect pulp volume. The aim of this study is to evaluate the dental pulp volume of central incisors in 3D images between individuals with and without CLP. [...] Read more.
Aim: Cleft lip and palate (CLP) patients have a greater predisposition to tooth malformation, which could affect pulp volume. The aim of this study is to evaluate the dental pulp volume of central incisors in 3D images between individuals with and without CLP. Materials and Methods: This retrospective case-control study is single-centered and was recruited between January 2016 and October 2022. Ninety-four patients who were followed in the Institute of Orthodontics were evaluated and divided into two groups: a control group of patients without CLP and a test group of patients with CLP. The 3D data were imported by 3D image semi-automatic segmenting software named ITK-SNAP to calculate tooth pulp volume. Results: The dental pulp volume for both groups, control and CLP, did not show statistically significant differences. In the cleft group, when comparing the pulp volume between the cleft side and the non-cleft side, the cleft side showed a smaller volume. Regarding age and sex, no statistically significant differences were observed. Conclusions: Although there are no differences in mean pulp volume between patients with and without CLP, there is a pulp volume reduction in the teeth on the cleft side when compared to the unaffected contralateral side. Full article
(This article belongs to the Special Issue Advanced Dental Biomaterials: Technologies and Applications)
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11 pages, 1215 KiB  
Article
Comparative Evaluation of Microhardness, Water Sorption and Solubility of Biodentin and Nano-Zirconia-Modified Biodentin and FTIR Analysis
by Rumesa Batul, Saleem D. Makandar, Mohamad Arif Bin Awang Nawi, Syed Nahid Basheer, Nassreen H. Albar, Ali A. Assiry, Alexander Maniangat Luke and Mohmed Isaqali Karobari
Appl. Sci. 2023, 13(3), 1758; https://doi.org/10.3390/app13031758 - 30 Jan 2023
Cited by 3 | Viewed by 1466
Abstract
Aim: This study compares the microhardness, water sorption and solubility of nano-zirconia-reinforced biodentin groups to commercially available biodentine. Materials and Methods: Samples were prepared by adding different percentages of nano zirconia to biodentin. Four groups were categorized as follows: group 1 used Biodentin [...] Read more.
Aim: This study compares the microhardness, water sorption and solubility of nano-zirconia-reinforced biodentin groups to commercially available biodentine. Materials and Methods: Samples were prepared by adding different percentages of nano zirconia to biodentin. Four groups were categorized as follows: group 1 used Biodentin as the control group, group 2 used 10% nano zirconia and 90% Biodentine, group 3 used 20% nano zirconia and 80% Biodentine, and group 4 used 30% nano zirconia and 70% Biodentine. A Vickers microhardness tester was used to measure the microhardness of the groups according to ISO 4049/2000. The water sorption and solubility of the divided groups were assessed using disk-shaped molds. The second weight was measured on an electronic weight machine after two weeks, and values were recorded. FTIR analysis was performed. Vickers microhardness, water sorption and solubility were analyzed using a one-way ANOVA, and for multiple comparisons, a post hoc Tukey’s HSD test with a significance level of p < 0.05 was performed. Group 3 had the highest mean microhardness measurement among all groups. The microhardness values for all groups in descending order are as follows: group 3, group 2, group 1 and group 4 (p = 0.008). Group 2 showed the lowest mean of water sorption compared among all groups. Group 2 has the lowest mean of water sorption, followed by group 3, group 1 and group 4 (p = 0.002). Group 4 showed the highest water sorption among all groups. Group 4 exhibited the highest solubility mean among all groups. Group 1 had the lowest mean of solubility, followed by group 2, group 3 and group 4 (p = 0.000). The FTIR spectra of different types of biodentin showed the absorbance peaks of the precipitates of each modified biodentin. The absorbance peaks fell between 474.63 cm−1 and 3438.33 cm−1. Conclusion: Biodentin is a competitive biomimetic material, but it lacks hardness and has more solubility. Thus, adding nano zirconia improved microhardness and reduced water sorption. The solubility of 20% nano zirconia added to biodentin was almost close to biodentin but with no significance. The 20% nano-zirconia-modified biodentin showed overall better properties compared to biodentin. The 20% nano-zirconia-modified biodentin can be used in deep cavities as a single restorative material instead of multi-layered restorations to increase longevity without microleakage and failure of restoration. Full article
(This article belongs to the Special Issue Advanced Dental Biomaterials: Technologies and Applications)
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