Hydrogels and Microgels: Fundamentals, Fabrication and Applications

A special issue of Applied Sciences (ISSN 2076-3417). This special issue belongs to the section "Chemical and Molecular Sciences".

Deadline for manuscript submissions: 31 May 2024 | Viewed by 1393

Special Issue Editors

School of Electronic Science and Engineering, University of Electronic Science and Technology of China, Chengdu 610054, China
Interests: hydrogel actuator; hydrogel sensor; flexible morphing skin; wearable device; flexible electromagnetic device; flexible robot
Ningbo Institute of Industrial Technology, Chinese Academy of Sciences, Ningbo 315201, China
Interests: bio-inspired; smart polymeric materials chemistry; polymeric hydrogels; fluorescent materials

Special Issue Information

Dear Colleagues,

Hydrogels and microgels are some of the most important members of flexible materials. With the continuous innovation of preparation methods and principles, hydrogels and microgels have application prospects in many high-tech fields. This Special Issue focuses on the fundamentals, preparation methods and potential applications of smart hydrogels or smart microgels, including but not limited to hydrogel sensors, flexible electromagnetic devices, hydrogel actuators, flexible structural design, wearable devices, variant structures, flexible morphing skin, etc. This Special Issue has a multidisciplinary feature and focuses on the smart properties of hydrogel materials, including but not limited to the synthesis of smart hydrogels or microgels, 4D printing molding, intelligent devices and structural design. Innovative research in relation to the basic principles and preparation methods is especially welcome.

Dr. Hetao Chu
Prof. Dr. Wei Lu
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Applied Sciences is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2400 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • flexible sensor
  • hydrogel actuator
  • flexible morphing skin
  • flexible electromagnetic device
  • flexible structure
  • wearable device
  • flexible robot
  • electronic skin
  • variant structure

Published Papers (2 papers)

Order results
Result details
Select all
Export citation of selected articles as:

Research

16 pages, 5299 KiB  
Article
Fluorescent Composite Cotton Fabric Modified with Crosslinked Chitosan for Theranostic Applications
Appl. Sci. 2023, 13(23), 12660; https://doi.org/10.3390/app132312660 - 25 Nov 2023
Viewed by 480
Abstract
Developing multifunctional textile material for wound dressing is challenging due to the variety of wounds and their differing healing stages. Therefore, theranostics replaces the traditional approach to provide patient comfort and accelerated healing. In this study, we developed and compared three different materials. [...] Read more.
Developing multifunctional textile material for wound dressing is challenging due to the variety of wounds and their differing healing stages. Therefore, theranostics replaces the traditional approach to provide patient comfort and accelerated healing. In this study, we developed and compared three different materials. For this purpose, for the first time, chitosan was modified with 4-nitro-1,8-naphthalic anhydride in N,N-dimethylformamide (DMF) suspension, and subsequent nucleophilic substitution of the nitro group with N,N-dimethylamino group, whereby chitosan with a yellow color and fluorescence was obtained. Cotton fabric was impregnated successively with a citric acid solution and solution from chitosan and chitosan modified with 1,8-naphthalimide fluorophore (CN material). The same experimental protocol was applied for the second material, but indomethacin was added to the chitosan solution (CNI material). The third material was prepared similarly to the second but was immersed in an alginate solution as a last step (CNIA material). The obtained materials have been characterized by optical and scanning electron microscopy and thermal analysis (TG-DTA-DTG). Indomethacin release from composite materials and hydrogel swelling and erosion in phosphate buffer pH 7.4 at 37 °C was examined using gravimetric analysis, UV-vis absorption, and fluorescence spectroscopy. The antimicrobial activity of the cotton samples has been evaluated against B. cereus and P. aeruginosa as model bacterial strains. The analysis showed that CN material inhibited about 98.8% of the growth of P. aeruginosa and about 95.5% of the growth of B. cereus. Other composite materials combine antimicrobial properties with a sustained release of biologically active substances that can observed visually. Full article
(This article belongs to the Special Issue Hydrogels and Microgels: Fundamentals, Fabrication and Applications)
Show Figures

Figure 1

13 pages, 5452 KiB  
Article
A Study on the Stoichiometry of Casein/Chitosan Gel Complexes as a Delivery System for Quercetin
Appl. Sci. 2023, 13(19), 10868; https://doi.org/10.3390/app131910868 - 30 Sep 2023
Viewed by 717
Abstract
As a well-known plant flavanol, quercetin possesses a diverse range of biological properties. These include its ability to act as an antioxidant, reduce inflammation, and exhibit anticancer effects. Consequently, it finds extensive application in numerous models related to wound healing. However, the poor [...] Read more.
As a well-known plant flavanol, quercetin possesses a diverse range of biological properties. These include its ability to act as an antioxidant, reduce inflammation, and exhibit anticancer effects. Consequently, it finds extensive application in numerous models related to wound healing. However, the poor physicochemical characteristics of the molecule (which include low solubility, stability, and permeability) eventually reduce its bioavailability at the targeted sites. A variety of nano formulations with great therapeutic potential have been created in order to get around these obstacles on the way to successful therapy. The current investigation aims to examine the properties of nano- and micro-sized casein/chitosan gel polyelectrolyte complexes (PECs) with respect to their potential for quercetin loading and release. Four different types of hydrogel particles at pH 6 and different casein/chitosan charge ratios were synthesized; namely, 1:1, 2:1, 4:1, and 6:1 in excesses of casein. The attractive electrostatic interactions between the oppositely charged polyelectrolytes were proved by FT-IR spectroscopy. The process yield increased from 37.5% to 72.5% in excesses of casein. The gel particle’s size varied between 377 nm and 5.72 µm depending on the casein/chitosan stoichiometry. The morphology of the obtained gel polyelectrolyte complexes was found to be spherical, based on scanning electron microscopy and atomic force microscopy analysis. The quercetin loading efficiency was above 95% for all investigated hydrogel complexes. Investigation of the physical state of the loaded polyphenol by the differential scanning calorimetry and X-ray powdered diffraction technique suggested the occurrence of partial recrystallization phenomena. The quercetin release test was performed in phosphate buffer (pH 5.5) at 32 °C and permanent stirring at 50 rpm. A zero-order model was used to describe in the best way the release kinetics. The reported casein/chitosan complexes loaded with quercetin may find application in wound healing as a concomitant treatment. Full article
(This article belongs to the Special Issue Hydrogels and Microgels: Fundamentals, Fabrication and Applications)
Show Figures

Figure 1

Back to TopTop