The Oral Microbiome in Periodontal Health and Disease

A special issue of Applied Sciences (ISSN 2076-3417). This special issue belongs to the section "Applied Biosciences and Bioengineering".

Deadline for manuscript submissions: 20 June 2024 | Viewed by 943

Special Issue Editor

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Guest Editor
1. Department of Periodontology, Faculty of Dental Medicine, University of Rijeka, Rijeka, Croatia
2. Department of Dental Medicine, Faculty of Dental Medicine and Health Osijek, J.J. Strossmayer University of Osijek, 31 000 Osijek, Croatia
Interests: periodontology; oral microbiome; dental biofilm; periodontal health; periodontal therapy

Special Issue Information

Dear Colleagues,

The oral microbiome is a community consisting of about 500 commensal, symbiotic and pathogenic bacterial species. A change in the balance of the oral microbiota leads to the development of oral diseases such as dental caries, and periodontal and peri-implant diseases and conditions. It is also associated with the development of systemic diseases, bacterial endocarditis, pneumonia and stroke.

Numerous research studies have focused on dental biofilm—from microbiology (in vitro and in vivo studies) to clinical practice (RCTs or other clinical trials)—but there remain various aspects of dental biofilm that have not been well investigated and explained.

This Special Issue will be focused on the oral microbiome in periodontal health and disease.

Prof. Dr. Davor Kuiš
Guest Editor

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  • dental biofilm
  • oral microbiome
  • periodontal health
  • periodontitis

Published Papers (1 paper)

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12 pages, 2964 KiB  
Effect of Chlorhexidine Digluconate on Oral Bacteria Adhesion to Surfaces of Orthodontic Appliance Alloys
by Doria Gergeta, Matea Badnjevic, Ljerka Karleusa, Zeljka Maglica, Stjepan Spalj and Ivana Gobin
Appl. Sci. 2024, 14(5), 2145; - 4 Mar 2024
Viewed by 618
This study aimed to analyse the effect of chlorhexidine digluconate (CHX DG) mouthwash on the adhesion of oral bacteria to orthodontic appliances. The interactions of four bacteria (S. mutans, A. actinomycetemcomitans, S. oralis, and V. parvula) with two [...] Read more.
This study aimed to analyse the effect of chlorhexidine digluconate (CHX DG) mouthwash on the adhesion of oral bacteria to orthodontic appliances. The interactions of four bacteria (S. mutans, A. actinomycetemcomitans, S. oralis, and V. parvula) with two alloys (stainless steel [SS] and nickel-titanium [NiTi]) and three CHX DG solutions (commercial products Curasept and Perio Plus, and pure CHX DG, all with 0.12% active substance) were tested. The adhesive effect on the orthodontic wires was evaluated after 24 h for S. oralis and after 72 h for the other bacteria. The minimum bactericidal concentration of the solution for each bacterial strain was determined using the dilution method to test the antibacterial action. Salivary-pretreated orthodontic archwires were exposed to minimal bactericidal concentrations of solution and bacteria. Commercial antiseptic products, especially Perio Plus, showed a better inhibition of bacterial adhesion to both alloys than pure CHX DG solution (p < 0.05). A. actinomycetemcomitans was most inhibited in the adhesion of all bacteria by the CHX DG products. A greater inhibition of streptococci adherence was observed on SS, while that of A. actinomycetemcomitans was observed on NiTi. V. parvula inhibition was product-dependent. Although there were differences between the strains and the tested agents, it can be concluded that Perio Plus most effectively inhibited the adhesion of all tested bacteria to the SS and NiTi alloys. A. actinomycetemcomitans was most sensitive to all tested agents, while S. mutans showed the highest resistance. The effectiveness of the tested agents was better on NiTi alloys. Full article
(This article belongs to the Special Issue The Oral Microbiome in Periodontal Health and Disease)
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