Neuroinflammation and Oxidative Stress Regulation in Neurovascular Diseases: Current and Future Perspective
A special issue of Antioxidants (ISSN 2076-3921).
Deadline for manuscript submissions: closed (15 June 2022) | Viewed by 482
Special Issue Editors
2. Department of Pharmacology and Personalised Medicine, School for Mental Health and Neurosciences (MeHNs), Maastricht University, Maastricht, The Netherlands
Interests: neurovascular diseases; brain ischemia; reactive oxygen species; network pharmacology; neuroinflammation; oxidative stress
Interests: neurovascular diseases; brain ischemia; tramatic brain injury; neuroinflammation; oxidative stress
Special Issue Information
Dear Colleagues,
Oxidative stress and neuroinflammation are common features of neurovascular and neurodegenerative diseases including stroke, vascular dementia, and Alzheimer’s disease, among others. In fact, increased oxidative stress levels due to the massive production of reactive oxygen/nitrogen species (ROS/RNS) directly lead to dysregulation of ROS/RNS-related signaling pathways, significantly contributing to the onset and progression of several neurovascular disorders. Moreover, oxidative stress-dependent tissue injury subsequently promotes the progression of a neuroinflammatory state characterized by the release of different pro-inflammatory mediators. In fact, both pathomechanisms are interconnected since specific inflammatory mediators use ROS production as signaling effectors. Thus, while dysregulated, these processes can contribute to neuronal cell loss and severe tissue damage in neurovascular diseases.
We invite you to submit your latest research findings either as an original or review article to our proposed Special Issue, “Neuroinflammation and Oxidative Stress regulation in Neurovascular diseases: Current and Future Perspectives”. We aim to gather the most recent research innovation regarding the role of oxidative stress and neuroinflammation in neurovascular disease. We encourage submissions including (i) different research models, i.e., in vitro, iPSC-derived cells, organoids, animal models, (ii) focusing on all nervous tissues and cell types, i.e., retina, brain, spinal cord, neurons, microglia, astrocytes, and (iii) using all types of molecular and cellular approaches, contributing to unravel pathophysiology and molecular mechanisms related to neurovascular disorders.
We look forward to your contribution.
Dr. Ana Casas Guijarro
Dr. Javier Egea
Guest Editors
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Antioxidants is an international peer-reviewed open access monthly journal published by MDPI.
Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2900 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
Keywords
- Neuroinflammation
- Oxidative stress
- Neurovascular diseases
- Stroke
- Vascular dementia
