Oxidative Stress and Redox Signaling in Neuro-Oncology
A special issue of Antioxidants (ISSN 2076-3921). This special issue belongs to the section "Health Outcomes of Antioxidants and Oxidative Stress".
Deadline for manuscript submissions: 30 May 2024 | Viewed by 148
Special Issue Editor
Interests: cancer; neuro-oncology; neurodegenerative diseases; pharmacology; inflammation; apoptosis
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
Cancers of the central nervous system (CNS), such as glioblastoma, are leading causes of death worldwide. Although CNS-related cancer development has been linked to hereditary and environmental factors, research has conclusively shown that oxidative stress and oxidative damage play pivotal roles contributing to the onset and spread of brain tumors. Damage stimulation and over-activation of oncogenes lead to the increased formation of reactive oxygen species (ROS). As a result, oxidative stress establishment can trigger the activation of several harmful factors, including growth factors, inflammatory cytokines, chemokines, and cell cycle regulatory molecules, that largely influence tumor growth and the risk of metastasis. In this regard, antioxidant approaches could possess therapeutic promise for cancer treatment since they are able to modulate various signaling pathways, often offering a more selective and better tolerated pharmacological approach than chemotherapy.
Therefore, this Special Issue aims to cover the current state of the art of preclinical studies and clinical studies that evaluate oxidative stress in the neuro-oncological field, including original research articles, literature reviews, and systematic reviews.
Dr. Irene Paterniti
Guest Editor
Manuscript Submission Information
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Keywords
- oxidative stress
- reactive oxygen species (ROS)
- neuro-oncology
