Impact of Oxidative Stress and Mitochondrial Dysfunction on the Regulation of Brain, Heart, Lung and Vascular Functions

A special issue of Antioxidants (ISSN 2076-3921). This special issue belongs to the section "Health Outcomes of Antioxidants and Oxidative Stress".

Deadline for manuscript submissions: 31 December 2024 | Viewed by 128

Special Issue Editor


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Guest Editor
Division of Clinical Pharmacology, Department of Medicine, Vanderbilt University Medical Center, Nashville, TN 37232, USA
Interests: oxidative stress; endothelial dysfunction; vascular dysfunction; systemic hypertension; pulmonary hypertension; mitochondrial dysfunction
Special Issues, Collections and Topics in MDPI journals

Special Issue Information

Dear Colleagues,

Redox and mitochondrial pathways play a critical role both in the homeostasis and the pathogenesis of cardiovascular disease, stroke, lung disease, cognitive decline and dementia; these diseases represent enormous healthcare and economic burden for society. Understanding the ethology of these conditions is critical to increase the healthspan of individuals and reduce the rates of morbidity and mortality. Multiple risk factors contribute to these pathological conditions. The old paradigm was to focus on systemic metabolic disorders; however, recent studies indicate that cell-specific mitochondria/metabolic dysregulation in the vascular cells promote pathological conditions independently from systemic alterations. This new paradigm provides novel insight into these pathways, such as accelerated vascular aging and crosstalk between cardiac and neurological conditions.

This Special Issue aims to be a platform where cross-disciplinary efforts addressing the gap of knowledge in this field could be disseminated.

Dr. Anna Dikalova
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Antioxidants is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2900 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • oxidative stress
  • mitochondrial dysfunction
  • cardiovascular disease
  • vascular dysfunction
  • ageing

Published Papers

This special issue is now open for submission.
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