Challenges for Therapeutic Drug Monitoring of Antimicrobials
A special issue of Antibiotics (ISSN 2079-6382).
Deadline for manuscript submissions: 15 June 2024 | Viewed by 1774
Special Issue Editors
Interests: infections in the elderly; surgical infections; sepsis; therapeutic drug monitoring; C. difficile infection; viral hepatitis
Interests: immunology; antimicrobials; HIV; antimicrobial stewardship; public health
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues，
TDM is frequently used in internal medicine, oncology and neurology. Although it has affected anti-infective agents since its inception, only in the last two decades has there been a greater use of TDM in the infectious diseases. TDM could help clinicians to administer correctly anti-infective drugs with a low therapeutic index.
Antimicrobial resistance represents one of the most major concerns to date and could lead to a dramatic global increase in mortality. Many efforts have been undertaken by scientific societies, which have led to antimicrobial stewardship and infection control. The use of TDM can be a great help for clinicians by allowing the effectiveness of a drug to be optimized, thereby reducing the onset of antimicrobial resistance; this advantage, already in physiological conditions, is even more noticeable in pathological conditions, such as during changes in the kinetics and dynamics of drugs (sepsis, pregnancy, cirrhosis, metabolic diseases, etc.); finally, the increase in medicalization of the global population has led to an increase in drug–drug interactions, which can be minimized with TDM.
The aim of this Special Issue is to focus on any aspects of TDM: pharmacokinetics and pharmacodynamics implications, clinical applications (in bacterial, fungal or viral infections), and real-life approaches in low-resource hospitals.
Different type of articles are welcome: original works, case reports, case series, qualitative and/or quantitative reviews of the current literature.
Dr. Giuseppe Pipitone
Prof. Dr. Giuseppe Nunnari
Dr. Fabrizio Taglietti
Guest Editors
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Antibiotics is an international peer-reviewed open access monthly journal published by MDPI.
Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2900 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
Keywords
- TDM
- antimicrobial resistance
- pharmacokinetics and pharmacodynamics implications
- bacterial infections
- fungal infections
- viral infections
