Special Issue "Breeding, Genetics and Safety Production of Dairy Cattle—Volume II"

A special issue of Agriculture (ISSN 2077-0472). This special issue belongs to the section "Farm Animal Production".

Deadline for manuscript submissions: 15 March 2024 | Viewed by 60

Special Issue Editors

College of Animal Science and Technology, Yangzhou University, Yangzhou 225009, China
Interests: milk fat traits; gene regulation network construction; gene expression; epigenetic; circRNA; lincRNA miRNA; mRNA
Special Issues, Collections and Topics in MDPI journals
College of Animal Science and Technology, Northwest A&F University, Yangling 712100, China
Interests: gene regulation; functional genomics; genetic polymorphisms; genetic heritability; gwas; bioinformatics; milk component; fatty acids; proteins
Special Issues, Collections and Topics in MDPI journals

Special Issue Information

Dear Colleagues,

Tens of thousands of years of wild animal domestication, natural selection, and artificial selection have led to the emergence of the livestock species we have all over the world today. With the improvement of genetic theories, conventional animal breeding techniques have developed from general phenotypic selection to the use of genetic methods to estimate breeding values. Moreover, great contributions have been made to the genetic improvement of livestock in the past few decades. Since the 1980s, the appearance of various molecular genetic markers and the development of modern biotechnology have provided new methods for improving animal genetic breeding. The integration of various omics information—such as DNA, RNA, protein, and epigenetic regulation—brings new opportunities for the mining of important economic traits of animals and the analysis of molecular genetic mechanisms. Functional genes can be mined and screened from different levels (including circRNA, lincRNA–miRNA, and mRNA) and perspectives by obtaining information on the genome, transcriptome, proteome, epigenome, and metagenome. In this way, gene networks and regulatory pathways can be studied more efficiently, thus laying a solid foundation for analysing the mechanisms of functional genes.

Over the last three decades, world milk production has increased by more than 59%, from 530 million tonnes to 843 million tonnes. Yet the genetic mechanisms behind milk fat traits remain largely undetermined. Milk is rich in fatty acids, proteins, and eight essential amino acids needed by the human body. The fatty acids in milk, namely, dodecylic acid, myristic acid, stearic acid, and palmitic acid, are the main energy substances in the human body, accounting for approximately 5, 10, 8, and 27% of the total fatty acids, respectively. Thus, decoding the genetics of milk fat traits can have a potential impact on product development, international trade, and consumption of milk components. This Special Issue will focus on applying the aforementioned advances to explore gene regulation and its molecular mechanisms in milk fat traits.

We would like to welcome investigators in relevant fields to contribute original research, reviews, and method articles. Potential subtopics of interest include, but are not limited to:

  • Research and application surrounding the genetic basis of important milk fat traits;
  • Mining and function of excellent genetic resources for milk fat traits;
  • Genetics of nutrition metabolism regulation and efficient production of milk fat;
  • Epigenetic research on genes implicated in milk fat traits;
  • High-throughput sequencing research surrounding genetics of milk fat traits;
  • Construction of gene (including circRNA, lincRNA–miRNA, and mRNA) expression regulatory network maps.

Dr. Zhi Chen
Dr. Cong Li
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Agriculture is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2600 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.


  • milk fat traits
  • gene regulation network construction
  • gene expression
  • epigenetic
  • circRNA
  • lincRNA–miRNA
  • mRNA

Published Papers

This special issue is now open for submission.
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