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Brief Report
Peer-Review Record

Serum Iron Level and 10-Year Survival after Melanoma

Biomedicines 2022, 10(12), 3018; https://doi.org/10.3390/biomedicines10123018
by Karolina Rowińska 1,*, Piotr Baszuk 1, Emilia Rogoża-Janiszewska 1, Jakub Deptuła 1, Wojciech Marciniak 1, Róża Derkacz 1, Marcin Lener 1, Cezary Cybulski 1, Magdalena Kiedrowicz 2, Magdalena Boer 2, Mariola Marchlewicz 2, Tadeusz Dębniak 1 and Jan Lubiński 1
Reviewer 1:
Reviewer 2:
Biomedicines 2022, 10(12), 3018; https://doi.org/10.3390/biomedicines10123018
Submission received: 20 October 2022 / Revised: 14 November 2022 / Accepted: 22 November 2022 / Published: 23 November 2022
(This article belongs to the Special Issue Role of Trace Elements in Chemoprevention and Cancer Therapy 2.0)

Round 1

Reviewer 1 Report

The manuscript presents interesting data

on survival of melanoma patients and

content of Fe in serum. There are minor points ro address.

Fig.1. Please prepare better quality Figure.
Best is to use Prism Graph Pad software.

2. Please, include in Discussion review of

opposite data, discuss differences between  

groups, explain potential reasons of

different results.

3. Add some limitations of the study.

Author Response

We have responded to all the reviewer's comments in the attached PDF. Thank you for preparing the review for our publication.

Author Response File: Author Response.pdf

Reviewer 2 Report

The authors describe the association of serum iron with prognosis of melanoma. High risk group shows poor prognosis in melanoma patients. These data are informative for management of melanoma. I have the following suggestions.

1.      Ferroptosis of melanoma was described in other paper (ex. PMID: 35309911). You should discuss about ferroptosis in melanoma.

2.      There are too many examples of past papers in the discussion part. Association of melanoma with iron should be more discussed.

Author Response

We have responded to all the reviewer's comments in the attached PDF. Thank you for preparing the review for our publication.

Author Response File: Author Response.pdf

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