Neurons Are a Primary Driver of Inflammation via Release of HMGB1
Abstract
:1. Introduction: Activation of Nociceptive Neurons Turns on Inflammation
2. Role of High Mobility Group Box 1 Protein (HMGB1) in the Inflammatory Response
3. HMGB1 Is Actively Released by Nociceptive Neurons
4. HMGB1 Induces Nociceptive Responses via Neuronal TLR4-Dependent Mechanisms
5. Neuronal HMGB1 Ablation/Neutralization Reduces Inflammation and Hyperalgesia
6. Perspective
Author Contributions
Funding
Conflicts of Interest
Abbreviations
References
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Yang, H.; Andersson, U.; Brines, M. Neurons Are a Primary Driver of Inflammation via Release of HMGB1. Cells 2021, 10, 2791. https://doi.org/10.3390/cells10102791
Yang H, Andersson U, Brines M. Neurons Are a Primary Driver of Inflammation via Release of HMGB1. Cells. 2021; 10(10):2791. https://doi.org/10.3390/cells10102791
Chicago/Turabian StyleYang, Huan, Ulf Andersson, and Michael Brines. 2021. "Neurons Are a Primary Driver of Inflammation via Release of HMGB1" Cells 10, no. 10: 2791. https://doi.org/10.3390/cells10102791