Topic Editors

Department of Orthopaedic and Trauma Surgery, Università Campus Bio-Medico di Roma, Via Alvaro del Portillo, 00128 Rome, Italy
Prof. Vicenzo Denaro
Full Professor and Consultant in Trauma and Orthopaedic Surgery, Department of Trauma and Orthopaedic Surgery, University Campus Bio-Medico of Rome, Via Álvaro Del Portillo, 200, 00128 Roma, Italy

Orthopaedic Diseases and Innovative Intervention Strategies, 2nd Volume

Abstract submission deadline
1 March 2025
Manuscript submission deadline
31 May 2025
Viewed by
2618

Topic Information

Dear Colleagues,

Innovations in technology and bioengineering are crucial in modern surgery. In particular, the continuous evolution of surgical techniques and assisted navigation systems has profoundly changed approaches to orthopaedic surgery. In addition, minimally invasive surgery, computer-assisted systems, virtual reality, and augmented and mixed reality now represent valuable and effective options for surgeons. The development of bioengineering has led to new coating materials for prostheses, ensuring more long enduring implants. All of these technological innovations are improving operating times as well as patient outcomes. In addition, the development of minimally invasive surgical techniques has resulted in continuous improvements in patient outcomes, including decreasing operating times, hospitalisations, rehabilitation, and post-surgical pain. These advantages have led to an increase in the number of operations, thus reducing hospital waiting lists. The development of new techniques and instruments for minimally invasive surgery is necessary to improve the quality of orthopaedic surgery, significantly in influencing healthcare costs. Therefore, scientific and technological progress in orthopaedics is essential for ensuring the best possible patient care. This topic aims to provide the latest scientific evidence regarding the most innovative intervention strategies currently available in all fields of orthopaedic surgery.

Prof. Dr. Umile Giuseppe Longo
Prof. Vincenzo Denaro
Topic Editors

Keywords

  • innovation
  • augmented reality
  • mixed reality
  • virtual reality
  • minimally invasive surgery
  • bioengineering
  • technologies

Participating Journals

Journal Name Impact Factor CiteScore Launched Year First Decision (median) APC
Journal of Clinical Medicine
jcm
3.9 5.4 2012 17.9 Days CHF 2600 Submit
Journal of Personalized Medicine
jpm
3.4 2.6 2011 17.8 Days CHF 2600 Submit
Medicina
medicina
2.6 3.6 1920 19.6 Days CHF 1800 Submit
Osteology
osteology
- - 2021 24 Days CHF 1000 Submit
Surgeries
surgeries
- - 2020 24.9 Days CHF 1200 Submit

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Published Papers (5 papers)

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10 pages, 222 KiB  
Article
Perioperative Blood Transfusion and Delirium after Total Knee or Hip Arthroplasty: Retrospective Analysis
by Saeyeon Kim, Tak-Kyu Oh and In-Ae Song
J. Pers. Med. 2024, 14(6), 576; https://doi.org/10.3390/jpm14060576 (registering DOI) - 28 May 2024
Viewed by 235
Abstract
We investigated the type of blood component transfusion associated with increased postoperative delirium. Adult patients who underwent total knee arthroplasty (TKA) or total hip arthroplasty (THA) between 2017 and 2022 were included. Delirium was evaluated and treated within two days after surgery. A [...] Read more.
We investigated the type of blood component transfusion associated with increased postoperative delirium. Adult patients who underwent total knee arthroplasty (TKA) or total hip arthroplasty (THA) between 2017 and 2022 were included. Delirium was evaluated and treated within two days after surgery. A total of 6737 patients (4112 TKA/2625 THA) were retrospectively studied; 2.48% of patients in the TKA (n = 102) and THA (n = 65) groups had postoperative delirium. The blood transfusion (BT) and non-BT groups had similar percentages of patients who experienced postoperative delirium (3.34 vs. 2.35%, p = 0.080). In the multivariable logistic regression model, BT was not associated with postoperative delirium—adjusted odds ratio (aOR): 1.03, confidence interval (CI): 0.62, 1.71; p = 0.917. Moreover, transfusion of packed red blood cells (p = 0.651), platelets (p = 0.998), and cryoprecipitate (p = 0.999) were not associated with delirium. However, transfusion of fresh frozen plasma was associated with a 5.96-fold higher incidence of delirium—aOR: 5.96, 95% CI: 2.72, 13.04; p < 0.001. In conclusion, perioperative BT was not associated with postoperative delirium in patients who underwent TKA or THA. However, FFP transfusion was associated with an increased incidence of postoperative delirium. Full article
8 pages, 2053 KiB  
Case Report
McCleery Syndrome Caused by Pectoralis Minor Hypertrophy Treated with Multimodal Physical Therapy—A Case Report
by Neven Starčević, Tadija Petrović, Tomislav Pavlović, Danijela Klarić and Dragan Primorac
J. Clin. Med. 2024, 13(10), 2894; https://doi.org/10.3390/jcm13102894 - 14 May 2024
Viewed by 324
Abstract
We present a case of a healthy young male professional water polo player who presented with swelling and pain in the upper arm and elbow after vigorous exercise. Diagnostic workup included an MRI and dynamic duplex ultrasound, which revealed compression of the axillary [...] Read more.
We present a case of a healthy young male professional water polo player who presented with swelling and pain in the upper arm and elbow after vigorous exercise. Diagnostic workup included an MRI and dynamic duplex ultrasound, which revealed compression of the axillary vein by a hypertrophic pectoralis minor muscle without thrombosis, constituting McCleery syndrome. This is a rare entity within the multiple thoracic outlet syndrome aetiologies. Taking a detailed history and physical examination complemented with diagnostic imaging are vital to the diagnosis. Afterward, the patient was treated with multimodal physical therapy and fully recovered and even exceeded his previous training and play level. Full article
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12 pages, 2178 KiB  
Systematic Review
How Effective Is Phage Therapy for Prosthetic Joint Infections? A Preliminary Systematic Review and Proportional Meta-Analysis of Early Outcomes
by Jason Young, Nicita Mehta, Sang Won Lee and Edward Kenneth Rodriguez
Medicina 2024, 60(5), 790; https://doi.org/10.3390/medicina60050790 - 9 May 2024
Viewed by 653
Abstract
Background and Objectives: Despite the promise of phage therapy (PT), its efficacy in prosthetic joint infection (PJI) management is unknown. Much of the current literature is largely limited to case reports and series. Materials and Methods: In order to help inform power calculations [...] Read more.
Background and Objectives: Despite the promise of phage therapy (PT), its efficacy in prosthetic joint infection (PJI) management is unknown. Much of the current literature is largely limited to case reports and series. Materials and Methods: In order to help inform power calculations for future clinical trials and comparative analyses, we performed a systematic review and proportional meta-analysis of early PT outcomes to provide a preliminary assessment of early phage therapy treatment outcomes for cases of PJI. Results: In a search of available literature across MEDLINE (Ovid, Wolters Kluwer, Alphen aan den Rijn, The Netherlands), Embase (Elsevier, Amsterdam, The Netherlands), the Web of Science Core Collection (Clarivate, London, UK), and Cochrane Central (Wiley, Hoboken, NJ, USA) up to 23 September 2023, we identified 37 patients with PJIs receiving adjunctive PT. Patients most frequently reported Staphylococcal species infection (95%) and intraarticular phage delivery (73%). Phage cocktail (65%) and antibiotic co-administration (97%) were common. A random-effects proportional meta-analysis suggested infection remission in 78% of patients (95% CI: 39%, 95%) (I2 = 55%, p = 0.08) and 83% with a minimum 12-month follow-up (95% CI: 53%, 95%) (I2 = 26%, p = 0.26). Conclusions: Our study provides a preliminary estimate of PT’s efficacy in PJIs and informs future comparative studies. Full article
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9 pages, 205 KiB  
Article
Comparison of Closed and Open Surgical Technique for Second to Fifth Metacarpal Shaft Fractures: A Multicenter, Retrospective Study in a Dutch City Population
by Marcel Libertus Johannes Quax, Maarten Kielman, Sven Albert Meylaerts and Alexander Pieter Antony Greeven
Surgeries 2024, 5(2), 264-272; https://doi.org/10.3390/surgeries5020024 - 18 Apr 2024
Viewed by 455
Abstract
The aim of this study was to assess surgical treatment in metacarpal shaft fractures of the second to fifth ray to determine the functional outcomes and complications in open reduction and internal fixation (ORIF) versus closed reduction and internal fixation (CRIF). This was [...] Read more.
The aim of this study was to assess surgical treatment in metacarpal shaft fractures of the second to fifth ray to determine the functional outcomes and complications in open reduction and internal fixation (ORIF) versus closed reduction and internal fixation (CRIF). This was a retrospective study that included patients with metacarpal shaft fractures of the second to fifth rays who were treated surgically between 1 January 2007 and 31 December 2019. Functional outcomes were scored using the QuickDASH and Eq5D score. A total of 231 treated patients were included. Single fractures were seen in 180 patients, and multiple fractures in 51 patients. ORIF was applied in 141 patients and CRIF in 90 patients. The functional outcomes were not significantly different between the groups. Complications were found in 41 (29%) of the ORIF patients and 15 (17%) of the CRIF patients. The functional outcomes after single or multiple metacarpal shaft fractures were similar in the ORIF and CRIF patients. ORIF showed significantly more complications, such as functional impairment and infections and a higher reoperation rate. In conclusion, CRIF is as safe as ORIF for the surgical treatment of metacarpal shaft fractures in terms of its functional outcome and slightly preferable due to its lower complication rate. Full article
10 pages, 514 KiB  
Review
Dual-Mobility Cups in Patients Undergoing Primary Total Hip Arthroplasty with Prior Lumbar Spine Fusion: A Systematic Review
by Tariq Ziad Issa, Adam Pearl, Emelia Moore, Hannan Ahmad Maqsood and Khaled J. Saleh
Surgeries 2024, 5(2), 125-134; https://doi.org/10.3390/surgeries5020014 - 25 Mar 2024
Viewed by 525
Abstract
Spine and hip abnormalities frequently occur together in most of the orthopedic population; therefore, both of these abnormalities impact the outcomes of the modalities that are being used. Few studies have reported reduced dislocation and revision rates with the use of dual-mobility cups [...] Read more.
Spine and hip abnormalities frequently occur together in most of the orthopedic population; therefore, both of these abnormalities impact the outcomes of the modalities that are being used. Few studies have reported reduced dislocation and revision rates with the use of dual-mobility cups (DMCs) in high-risk lumbar spine fusion (LSF) patients undergoing primary total hip arthroplasty (THA). This study aims to clarify the relationship between pre-existing lumbar spinal fusion and the outcomes of THA with dual-mobility constructs. We systematically reviewed the current literature through several online databases following PRISMA protocol and the Cochrane Handbook for Systematic Reviews of Interventions. We used the methodological index for non-randomized studies (MINORS) to evaluate the methodological quality of the included trials. Four studies examined the feasibility and effectiveness of dual-mobility cups in patients undergoing primary THA with prior LSF. Two studies were conducted in the United States, while the other two originated in Finland and France, respectively. The included studies enrolled 284 patients. Most of these patients had instrumented fusions. Seventy-eight percent of patients received one- or two-level fusions. The average age across the studies was 68.22 and the mean body mass index was 28. No cases of postoperative DMC implant dislocations were identified. The incidence of postoperative complications was 6% (10/173), including deep venous thrombosis, periprosthetic loosening, infection, and fracture, greater trochanteric fracture, and superficial wound infections. Most included studies had some methodological limitations, with an average MINORS score of 10.5 ± 5.8. The use of dual-mobility cups in these high-risk patients undergoing total hip arthroplasty may lead to reduced dislocation rates and postoperative complications. Further long-term follow-up studies are warranted to support these findings. Full article
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