Topic Editors

Department of Cranio- and Maxillofacial Surgery, Hospital of the University of Regensburg, Franz-Josef-Strauß-Allee 11, 93053 Regensburg, Germany
Dr. Miroslaw J Szczepanski
Department of Biochemistry, Medical University of Warsaw, Banacha 1 Str., 02-097 Warsaw, Poland

The Role of Extracellular Vesicles as Modulators of the Tumor Microenvironment

Abstract submission deadline
31 December 2024
Manuscript submission deadline
30 June 2025
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Topic Information

Dear Colleagues,

The tumor microenvironment (TME) is a complex and dynamic ecosystem that influences tumor progression, invasion, metastasis, and treatment response. It is composed of cancer cells, stromal cells, immune cells, and various components of the extracellular matrix and recent research indicates that these components communicate with each other via extracellular vesicles (EVs). EVs are small membrane-bound vesicles released by almost all cells, including cancer cells, and are known to carry various bioactive molecules, such as proteins, nucleic acids, and lipids. This topic is dedicated to the emerging understanding of how EVs contribute to the modulation of the TME. Hereby, we focus on a variety of EV-related aspects, including, but not limited to, EVs as modulators of intercellular communication, the role of EVs in remodeling the extracellular matrix, the immunomodulatory effects of EVs, and EVs as biomarkers and therapeutic targets. We hope that this topic will provide further insights into the complex role of EVs in modulating the TME and will accelerate the development of novel EV-based therapeutic strategies.

Dr. Nils Ludwig
Dr. Miroslaw J Szczepanski
Topic Editors


  • extracellular vesicles
  • exosomes
  • tumor microenvironment
  • intercellular communication
  • immunomodulation

Participating Journals

Journal Name Impact Factor CiteScore Launched Year First Decision (median) APC
5.5 8.3 2011 19.2 Days CHF 2700 Submit
Current Issues in Molecular Biology
3.1 2.4 1999 16.5 Days CHF 2000 Submit
Scientia Pharmaceutica
2.5 6.4 1930 21.7 Days CHF 1000 Submit
5.2 7.4 2009 18.2 Days CHF 2900 Submit
Current Oncology
2.6 2.6 1994 18.4 Days CHF 2200 Submit
6.0 9.0 2012 18.8 Days CHF 2700 Submit

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Published Papers

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