Zoonotic Diseases: Understanding the Intersection between Animal and Human Health

A special issue of Zoonotic Diseases (ISSN 2813-0227).

Deadline for manuscript submissions: 15 August 2024 | Viewed by 7313

Special Issue Editors

Section of Infectious Diseases, Department of Internal Medicine, School of Medicine, Yale University, New Haven, CT 06520, USA
Interests: immunology; malaria; tuberculosis; cell signaling; synthetic biology
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Guest Editor
Department of Pathology, College of Medicine, University of Illinois, Chicago, IL 60612, USA
Interests: host-pathogen interaction; regenerative biology; immunology; microbiology; bacterial drug resistance; metabolic pathways discovery
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Guest Editor
School of Medicine, New York University, New York, NY 10016, USA
Interests: phage therapeutics; microbiology; virology; molecular biology

Special Issue Information

Dear Colleagues, 

Zoonotic diseases have been historically associated with humans since the beginning of civilization. Zoonotic diseases have caused significant pandemics, such as bubonic plague, and the Spanish flu of 1918. In recent years, there has been a surge in new zoonotic diseases and the spread of existing outbreaks to new regions. As a result, there has been a growing concern about the impact on health and economic impact from these diseases. Pathogens, including bacteria, viruses, fungi, and parasites, can cause zoonotic diseases. Some well-known zoonotic diseases are Rabies, Plague, Lyme disease, and West Nile virus, while relatively new and not well-understood diseases include SARS, Ebola, MERS, and Swine flu. There are many challenges in the fight against zoonotic diseases, including the emergence of new zoonotic diseases, lack of diagnostics methods, lack of awareness and knowledge, lack of coordination and collaboration among nations, changing environment and ecological conditions, and ease of travel.

 In conclusion, zoonotic diseases pose a serious threat to both human health and the stability of the economy. The ongoing management of zoonotic diseases necessitates a commitment to collaboration, sharing information, raising public awareness, and developing coordinated response plans. With continued effort and collaboration, it is possible to minimize the impact of zoonotic diseases and protect human, animal, and environmental health.

This Special Issue accepts submissions of original research articles, reviews, mini-reviews, and commentaries covering all aspects of zoonotic disease.

Dr. Gunjan Arora
Dr. Aditya Sharma
Dr. Neha Dhasmana
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Zoonotic Diseases is an international peer-reviewed open access quarterly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 1000 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • zoonotic diseases
  • zoonotic and public health
  • emerging diseases
  • vector-borne disease
  • infectious diseases
  • microbiology
  • virology
  • parasitology
  • transmission
  • management of zoonosis diseases
  • epidemic
  • global health diseases

Published Papers (4 papers)

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Editorial

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3 pages, 238 KiB  
Editorial
Bridging the Gap: Exploring the Connection between Animal and Human Health
by Aditya Kumar Sharma, Neha Dhasmana and Gunjan Arora
Zoonotic Dis. 2023, 3(2), 176-178; https://doi.org/10.3390/zoonoticdis3020014 - 28 May 2023
Cited by 2 | Viewed by 1736
Abstract
Zoonotic diseases, also referred to as zoonoses, are diseases that are transmitted from animals to humans [...] Full article

Research

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17 pages, 1457 KiB  
Article
Exploring Pathogenic and Zoonotic Bacteria from Wild Rodents, Dogs, and Humans of the Ngorongoro District in Tanzania Using Metagenomics Next-Generation Sequencing
by Amina Ramadhani Issae, Abdul Selemani Katakweba, Rose Peter Kicheleri, Augustino Alfred Chengula, Marco van Zwetselaar and Christopher Jacob Kasanga
Zoonotic Dis. 2023, 3(3), 226-242; https://doi.org/10.3390/zoonoticdis3030019 - 01 Sep 2023
Viewed by 1627
Abstract
Globally, zoonoses have serious consequences due to their socioeconomic impacts. Ngorongoro District is home to a diverse range of wildlife and domestic animals, including rodents and dogs, which often coexist in close proximity with humans. The aim of the study was to identify [...] Read more.
Globally, zoonoses have serious consequences due to their socioeconomic impacts. Ngorongoro District is home to a diverse range of wildlife and domestic animals, including rodents and dogs, which often coexist in close proximity with humans. The aim of the study was to identify the zoonotic bacteria present in wild rodents, domestic dogs, and humans using metagenomics next-generation sequencing technology. A cross-sectional study was conducted in 2022. This study used both Illumina and Oxford Nanopore sequencing technologies to identify bacteria in 530 blood samples collected from humans (n = 200), wild rodents (n = 230), and dogs (n = 100). Several zoonotic airborne/contagious bacteria, including Mycobacterium spp., Mycoplasma spp., Bordetella spp., and Legionella spp., were detected in wild rodents, domestic dogs, and humans. Arthropod-borne zoonotic bacteria such as Bartonella spp., Borrelia spp., and Rickettsia spp. were detected in all three hosts, while Orientia spp. was found in wild rodents and domestic dogs. Yersinia pestis, Streptobacillus spp. and Anaplasma spp. were found only in wild rodents. Other zoonotic bacteria found shared among wild rodents, domestic dogs, and humans are Leptospira spp., Brucella spp., and Salmonella spp. Generally, wild rodents had the highest prevalence of zoonotic bacterial species when compared to domestic dogs and humans. The detection of zoonotic bacteria in rodents, dogs, and humans supports the hypothesis that infections can spread between animals and humans sharing the same environment. Full article
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Review

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17 pages, 667 KiB  
Review
Bacterial Zoonotic Diseases and Male Reproduction
by Lateef Olabisi Okeleji, Lydia Oluwatoyin Ajayi, Aduragbemi Noah Odeyemi, Victor Amos, Bosede Grace Akanbi, Moyinoluwa Comfort Onaolapo, Bolade Sylvester Olateju, Wale Johnson Adeyemi and Ayodeji Folorunsho Ajayi
Zoonotic Dis. 2024, 4(1), 97-113; https://doi.org/10.3390/zoonoticdis4010010 - 19 Mar 2024
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Abstract
Bacterial zoonotic diseases hold significant public health importance due to their substantial contribution to human morbidity and mortality. These infections have been implicated in reducing the fertility rate among couples of reproductive age. Despite the increasing prevalence of infertility and sub-fertility in men, [...] Read more.
Bacterial zoonotic diseases hold significant public health importance due to their substantial contribution to human morbidity and mortality. These infections have been implicated in reducing the fertility rate among couples of reproductive age. Despite the increasing prevalence of infertility and sub-fertility in men, there has been limited investigation into the possible effects of bacterial zoonotic infections on the male reproductive system. The purpose of this review is to describe common bacterial zoonotic diseases and their effects on human reproduction in order to unveil the hidden roles these infections could play in male factor infertility. While there is a dearth of information on this subject from human studies, available evidence from experimental animals suggests that bacterial zoonotic diseases impair male reproductive functions and structures primarily through the activation of the inflammatory response and distortion of the antioxidant system, resulting in the generation of oxidative species. In light of the limited research on bacterial zoonotic diseases and their role in male reproduction, efforts must be directed towards the subject to unravel the underlying pathological mechanisms and reduce the incidence among the human populace, either through preventive or curative measures. Full article
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15 pages, 2312 KiB  
Systematic Review
Zoonotic Diseases in Sub-Saharan Africa: A Systematic Review and Meta-Analysis
by Jérôme Ateudjieu, Joseph Nelson Siewe Fodjo, Calson Ambomatei, Ketina Hirma Tchio-Nighie and Anne-Cecile Zoung Kanyi Bissek
Zoonotic Dis. 2023, 3(4), 251-265; https://doi.org/10.3390/zoonoticdis3040021 - 04 Oct 2023
Viewed by 2309
Abstract
Frequent animal–human interactions in sub-Saharan Africa (SSA) pose an increased risk for the transmission of zoonotic diseases. While there are sporadic reports of zoonotic diseases outbreaks in SSA, a synthetic overview is necessary to better understand how the sub-region is impacted by these [...] Read more.
Frequent animal–human interactions in sub-Saharan Africa (SSA) pose an increased risk for the transmission of zoonotic diseases. While there are sporadic reports of zoonotic diseases outbreaks in SSA, a synthetic overview is necessary to better understand how the sub-region is impacted by these pathologies. We conducted a systematic review of zoonotic diseases studies conducted in SSA between 2000 and 2022. Quantitative reports including case reports/series from countries spanning West, Central, East, and Southern SSA and that provided empirical data on the occurrence of zoonotic diseases in humans with documented evidence of animal origin were eligible for inclusion. The 55 eligible articles provided 82 reports of zoonotic diseases for a total of 28,934 human cases (pooled attack rate: 54.4 per 1000) and 1182 deaths (pooled fatality rate: 345.4 per 1000). Only 31 (37.8%) of the studies were conducted during ongoing outbreaks. We identified the zoonotic diseases in SSA with the highest attack rates (rickettsiosis, toxoplasmosis, Q-fever) and CFR (Marburg, Ebola, leptospirosis), which should be prioritized for surveillance and response preparedness. Addressing the threat of zoonotic diseases in SSA requires the strengthening of health systems and implementation of a one health approach. Importantly, research should be encouraged during ongoing epidemics to fortify immediate response strategies and work toward preventing future outbreaks. Full article
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