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Journals
Vaccines
Special Issues
Oral Delivery and Related ADME Studies of Vaccines
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Oral Delivery and Related ADME Studies of Vaccines

A special issue of Vaccines (ISSN 2076-393X). This special issue belongs to the section "Vaccine Efficacy and Safety".

Deadline for manuscript submissions: closed (31 December 2023) | Viewed by 4776

Special Issue Editors

Dr. Saurav Kumar Jha

E-Mail Website
Guest Editor
Research and Development Department, Curex Pharmaceutical Private Limited, Banepa, Nepal
Interests: oral delivery of proteins and peptide; BCS IV class drugs; vaccines; pharmacokinetics study; toxicity studies
Dr. Keshav Raj Paudel

E-Mail Website
Guest Editor
Faculty of Science, University of Technology Sydney, Ultimo, NSW, Australia
Interests: atherosclerosis; vascular inflammation; cell migration; cell proliferation; rat model of vascular injury; obesity; inflammation marker; in vitro experiment; lung cancer, asthma; antioxidants; COPD; extracellular vesicles; breast cancer
Special Issues, Collections and Topics in MDPI journals

Special Issue Information

Dear Colleagues,

We would like to invite you to submit your research and review papers to a Special Issue of Vaccines entitled as "Oral delivery and related ADME studies of Vaccines". All the potential manuscripts regarding development of various technologies for the delivery of vaccines through oral routes; and evaluation of its therapeutical potential will be given priority for publication.

Dr. Saurav Kumar Jha
Dr. Keshav Raj Paudel
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Vaccines is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2700 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • oral delivery
  • bioavailabilities
  • ADME
  • therapeutic efficacy
  • therapeutic drug monitoring
  • stability studies
  • toxicity
  • carrier-mediated drug transport

Published Papers (1 paper)

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Review

20 pages, 1835 KiB  
Review
Recent Developments in Oral Delivery of Vaccines Using Nanocarriers
by Amna Zafar, Raffia Arshad, Asim Ur.Rehman, Naveed Ahmed and Hashaam Akhtar
Vaccines 2023, 11(2), 490; https://doi.org/10.3390/vaccines11020490 - 20 Feb 2023
Cited by 4 | Viewed by 4088
Abstract
As oral administration of vaccines is the preferred route due to its high patient compliance and ability to stimulate both cellular and humoral immune responses, it is also associated with several challenges that include denaturation of vaccine components in the acidic environment of [...] Read more.
As oral administration of vaccines is the preferred route due to its high patient compliance and ability to stimulate both cellular and humoral immune responses, it is also associated with several challenges that include denaturation of vaccine components in the acidic environment of the stomach, degradation from proteolytic enzymes, and poor absorption through the intestinal membrane. To achieve effective delivery of such biomolecules, there is a need to investigate novel strategies of formulation development that can overcome the barriers associated with conventional vaccine delivery systems. Nanoparticles are advanced drug delivery carriers that provide target-oriented delivery by encapsulating vaccine components within them, thus making them stable against unfavorable conditions. This review provides a detailed overview of the different types of nanocarriers and various approaches that can enhance oral vaccine delivery. Full article
(This article belongs to the Special Issue Oral Delivery and Related ADME Studies of Vaccines)
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