Epidemiological Approaches to Understanding the Role of Environmental and Sociodemographic Factors in Vaccine-Preventable Diseases

A special issue of Vaccines (ISSN 2076-393X). This special issue belongs to the section "Human Vaccines and Public Health".

Deadline for manuscript submissions: 31 May 2024 | Viewed by 4477

Special Issue Editors


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Guest Editor
School of Public Health and Social Work, Queensland University of Technology, Brisbane, QLD 4000, Australia
Interests: climate change and infectious disease transmission; GIS and spatiotemporal model; biostatistics; environmental epidemiology; development of early warning systems for infectious diseases
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Guest Editor
School of Public Health and Social Work, Queensland University of Technology, Brisbane, Australia
Interests: environmental health and infectious diseases; GIS and spatiotemporal modelling; Bayesian statistics; information systems

Special Issue Information

Dear Colleagues,

The international and multidisciplinary efforts to develop vaccines and other public health strategies to address the Covid-19 pandemic demonstrated our capacity to respond to health issues with global impact but also highlighted the looming threat of emerging infectious diseases. The immune response to viral, bacterial and human parasitic infections depends on complex biological mechanisms that can be determined by environmental and sociodemographic factors which are not always well-known or established. These factors can also affect the effectiveness of vaccination programs and disease prevention strategies. This special issue of Vaccines is dedicated to recognising quality research studies on the major challenge of understanding the role of environmental and sociodemographic factors on the spread of vaccine-preventable diseases and the implementation of immunisation strategies. We want to acknowledge the increasing and consistent research on methodological analyses to understand the relationship between socio-environmental factors and the prevention of these infections as well as new developments that consider an environmental health approach and epidemiological modelling. This special issue aims to provide updated and high-quality evidence to support prevention strategies with an emphasis on vaccination to address the significant and increasing challenges posed by infections that include (but are not limited to): Influenza, Japanese encephalitis, Yellow fever, Pneumococcal and Meningococcal disease, Rotavirus, Tetanus (non-neonatal), Dengue, Ebola, Hepatitis (A/B), Mumps, Typhoid, Varicella, Rubella, Measles, Malaria, Leishmaniasis and Schistosomiasis, as well as emerging infections such as COVID-19 and Monkeypox.

Prof. Dr. Wenbiao Hu
Dr. Javier Cortes-Ramirez
Guest Editors

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Keywords

  • vaccine-preventable diseases
  • prevention strategies
  • sociodemographic and environmental risk factors
  • emerging infections
  • epidemiological modelling
  • immunization strategies

Published Papers (3 papers)

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Research

16 pages, 853 KiB  
Article
Pervasive Parental Hesitancy and Resistance towards Measles Rubella Vaccination in Jordan
by Muna Barakat, Maram Abdaljaleel, Nada Atawneh, Rawan Alkhazaleh, Dana Aburumman, Eman Hamed and Malik Sallam
Vaccines 2023, 11(11), 1672; https://doi.org/10.3390/vaccines11111672 - 31 Oct 2023
Cited by 2 | Viewed by 1410
Abstract
Measles remains a highly contagious and potentially severe infectious disease, necessitating high vaccine coverage. However, misinformation and measles vaccine hesitancy/resistance have posed significant challenges to achieving this goal. The COVID-19 pandemic further exacerbated these challenges, leading to a measles outbreak in Jordan in [...] Read more.
Measles remains a highly contagious and potentially severe infectious disease, necessitating high vaccine coverage. However, misinformation and measles vaccine hesitancy/resistance have posed significant challenges to achieving this goal. The COVID-19 pandemic further exacerbated these challenges, leading to a measles outbreak in Jordan in 2023. This study aimed to investigate the acceptance of the measles rubella (MR) vaccine among parents in Jordan and to identify its associated determinants. This cross-sectional questionnaire-based study was conducted using a previously Arabic-validated version of the Parental Attitudes towards Childhood Vaccines (PACV) survey instrument. Data collection took place in October 2023, and the final study sample comprised a total of 391 parents, with mothers representing 69.8% of the participants (n = 273). The majority of participating parents expressed either resistance (n = 169, 43.2%) or hesitancy (n = 168, 43.0%) towards MR vaccination, while only 54 participants (13.8%) expressed MR vaccine acceptance. Multivariate analysis revealed that trust in vaccine safety/efficacy, behavior, and having fewer offspring were significantly associated with MR vaccine acceptance. The current study revealed a concerning level of MR vaccine hesitancy/resistance among parents in Jordan, which could signal a public health alarm in the country. Urgent and targeted interventions are strongly recommended to address this issue, including mass campaigns aimed at building trust in the MR vaccine’s safety/efficacy. Additionally, there is an urgent need for effective public health initiatives to ensure sufficient measles vaccine coverage to prevent future outbreaks of this serious disease. Full article
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27 pages, 630 KiB  
Article
Predictors for Uptake of Vaccines Offered during the Second Year of Life: Second Dose of Measles-Containing Vaccine and Meningococcal Serogroup A-Containing Vaccine, Ghana, 2020
by Pierre Muhoza, Monica P. Shah, Hongjiang Gao, Kwame Amponsa-Achiano, Pamela Quaye, William Opare, Charlotte Okae, Philip-Neri Aboyinga, Kwadwo L. Opare, Melissa T. Wardle and Aaron S. Wallace
Vaccines 2023, 11(10), 1515; https://doi.org/10.3390/vaccines11101515 - 23 Sep 2023
Viewed by 1056
Abstract
Background: Understanding the drivers of coverage for vaccines offered in the second year of life (2YL) is a critical focus area for Ghana’s life course approach to vaccination. This study characterizes the predictors of vaccine receipt for 2YL vaccines—meningococcal serogroup A conjugate vaccine [...] Read more.
Background: Understanding the drivers of coverage for vaccines offered in the second year of life (2YL) is a critical focus area for Ghana’s life course approach to vaccination. This study characterizes the predictors of vaccine receipt for 2YL vaccines—meningococcal serogroup A conjugate vaccine (MACV) and the second dose of measles-containing vaccine (MCV2)—in Ghana. Methods: 1522 children aged 18–35 months were randomly sampled through household surveys in the Greater Accra Region (GAR), Northern Region (NR), and Volta Region (VR). The association between predictors and vaccination status was modeled using logistic regression with backwards elimination procedures. Predictors included child, caregiver, and household characteristics. Results: Coverage was high for infant vaccines (>85%) but lower for 2YL vaccines (ranging from 60.2% for MACV in GAR to 82.8% for MCV2 in VR). Predictors of vaccination status varied by region. Generally, older, first-born children, those living in rural settlements and those who received their recommended infant vaccines by their first birthday were the most likely to have received 2YL vaccines. Uptake was higher among those with older mothers and children whose caregivers were aware of the vaccination schedule. Conclusions: Improving infant immunization uptake through increased community awareness and targeted strategies, such as parental reminders about vaccination visits, may improve 2YL vaccination coverage. Full article
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15 pages, 1445 KiB  
Article
Combined Impact of Omicron Vaccination and Environmental Risk Exposure: A Thailand Case Study
by Weerawat Ounsaneha, Orapin Laosee, Thunwadee Tachapattaworakul Suksaroj and Cheerawit Rattanapan
Vaccines 2023, 11(2), 297; https://doi.org/10.3390/vaccines11020297 - 29 Jan 2023
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Abstract
This research aimed to determine the levels of COVID-19 booster dose vaccinations in Thai populations in areas with environmental risk exposure during the Omicron outbreak. Five of twenty provinces in Thailand were selected by assessing environmental risk exposure for study settings. A total [...] Read more.
This research aimed to determine the levels of COVID-19 booster dose vaccinations in Thai populations in areas with environmental risk exposure during the Omicron outbreak. Five of twenty provinces in Thailand were selected by assessing environmental risk exposure for study settings. A total of 1038 people were interviewed by a structured questionnaire. The predicting factors of COVID-19 booster dose vaccinations were analyzed by univariate and multivariate analysis. The results showed that 69.4% (95% CI 66.5–72.1) of the population was vaccinated with COVID-19 booster doses. Multiple logistics regression revealed that the female gender (AOR 1.49, 95% CI 1.11–2.00), all age groups from 38 to 60 years old, all education levels of at least secondary school, high income (AOR 1.16, 95% CI 1.15–2.24), populations having experience with COVID-19 infection (AOR 2.27, 95% CI 2.05–3.76), knowledge of vaccine (AOR 1.78, 95% CI 1.11–2.83), and trusting attitude (AOR 1.76, 95% CI 1.32–2.36) were factors among those more likely to take COVID-19 booster dose vaccinations in high-environmental-risk-exposure areas. Therefore, an effective booster dose campaign with education programs to increase attitudes toward booster vaccinations should be implemented for the resilience of COVID-19 prevention and control. Full article
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