Dear Colleagues,

The incidence of invasive fungal infections has risen in recent decades, especially in immunocompromised patients. The monitoring and early and accurate diagnosis of these infections are crucial for the proper management of these diseases. The above is relevant for several reasons: the availability of precise and timely diagnoses could reduce the use of empirical antifungal therapy, thereby reducing antifungal selection pressure and the emergence of antifungal resistance. Failure to diagnose and treat these infections in a timely manner can have serious and potentially fatal consequences. Unfortunately, the prompt diagnosis of these infections can often be exceedingly challenging. Classical microbiologic and histopathologic approaches generally are neither sensitive nor specific. Moreover, invasive fungal infections are frequently not detected until the advanced stages of the disease. Given the potential impact of early diagnosis on treatment efficacy and mortality prevention, there has been a significant focus on the development of non-culture methods for diagnosing fungal infections.

We invite our colleagues in the scientific community to submit both original and review articles related to novel approaches to the identification of fungi involved in IFI or focused on the host immune responses to fungal antigens, the detection of specific macromolecular antigens utilizing immunological reagents, the amplification and detection of fungal nucleic acid sequences, and the quantification of fungal metabolite products.

Dr. Eduardo Alvarez Duarte
Dr. Esperanza Duarte-Escalante
Dr. María Guadalupe Frías-De-León
Guest Editors

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• invasive fungal infections
• monitoring
• diagnosis
• biomarkers
• fungal culture
• monitoring strategies
• clinical management

Potential Authors:

1. Eduardo García Salazar,

Tentative Title: The role of "omics" in the diagnosis of invasive fungal infections