Risk Assessment and Control of Mycotoxins

A special issue of Toxins (ISSN 2072-6651). This special issue belongs to the section "Mycotoxins".

Deadline for manuscript submissions: closed (30 September 2022) | Viewed by 3024

Special Issue Editor


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Guest Editor
Department of Veterinary Medicine and Animal Productions, University of Naples “Federico II”, Via Federico Delpino n.1, 80137 Naples, Italy
Interests: aflatoxin B1; kidney; ROS; oxidative stress; feed additive; poultry; ochratoxin A; mycotoxin-binders
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Special Issue Information

Dear Colleagues,

Mycotoxins are still an important topic of research and discussion in the scientific community today. In order to understand the negative implications of mycotoxicoses on human and animal health, which cause serious economic losses due to their presence worldwide, we believe it is necessary to investigate the main biochemical mechanisms of action with which mycotoxins act. The correlation between oxidative stress and mycotoxin-induced toxicity, such as ochratoxin and aflatoxin, is known. Therefore, the attention of the scientific community is directed towards the identification of natural antioxidant compounds with free radical scavenging capacities to combat mycotoxin-induced toxicity.

For this Special Issue, we look forward to receiving researchers’ contributions in the form of original research, case studies, or review papers, giving new aspects and results to the understanding of the effects of natural antioxidant compounds on various mycotoxins in feed, and their implications for disease development in farm and laboratory animals under both experimental and realistic conditions.

Dr. Roberto Ciarcia
Guest Editor

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Keywords

  • lipid peroxidation
  • DNA damage
  • oxidative stress
  • cellular and molecular mechanisms
  • toxic effects
  • animal health

Published Papers (1 paper)

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Review

15 pages, 511 KiB  
Review
Ochratoxin A and Kidney Oxidative Stress: The Role of Nutraceuticals in Veterinary Medicine—A Review
by Consiglia Longobardi, Gianmarco Ferrara, Emanuela Andretta, Serena Montagnaro, Sara Damiano and Roberto Ciarcia
Toxins 2022, 14(6), 398; https://doi.org/10.3390/toxins14060398 - 9 Jun 2022
Cited by 14 | Viewed by 2620
Abstract
The problem of residues of toxic contaminants in food products has assumed considerable importance in terms of food safety. Naturally occurring contaminants, such as mycotoxins, are monitored routinely in the agricultural and food industries. Unfortunately, the consequences of the presence of mycotoxins in [...] Read more.
The problem of residues of toxic contaminants in food products has assumed considerable importance in terms of food safety. Naturally occurring contaminants, such as mycotoxins, are monitored routinely in the agricultural and food industries. Unfortunately, the consequences of the presence of mycotoxins in foodstuffs are evident in livestock farms, where both subacute and chronic effects on animal health are observed and could have non-negligible effects on human health. Ochratoxin A (OTA) is a common mycotoxin that contaminates food and feeds. Due to its thermal stability, the eradication of OTA from the food chain is very difficult. Consequently, humans and animals are frequently exposed to OTA in daily life. In this review article, we will devote time to highlighting the redox-based nephrotoxicity that occurs during OTA intoxication. In the past few decades, the literature has improved on the main molecules and enzymes involved in the redox signaling pathway as well as on some new antioxidant compounds as therapeutic strategies to counteract oxidative stress. The knowledge shown in this work will address the use of nutraceutical substances as dietary supplements, which would in turn improve the prophylactic and pharmacological treatment of redox-associated kidney diseases during OTA exposure, and will attempt to promote animal feed supplementation. Full article
(This article belongs to the Special Issue Risk Assessment and Control of Mycotoxins)
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