Wastewater-Based Epidemiology Biomarkers: Analysis, Occurrence and Fate in Wastewater

A special issue of Toxics (ISSN 2305-6304). This special issue belongs to the section "Environmental Chemistry".

Deadline for manuscript submissions: closed (20 November 2021) | Viewed by 4146

Special Issue Editors


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Guest Editor
1) Laboratory of Analytical Chemistry, Department of Chemistry, National and Kapodistrian University of Athens, Panepistimiopolis Zografou, 15771 Athens, Greece;
2) Queensland Alliance for Environmental Health Sciences (QAEHS), The University of Queensland, 20 Cornwall Street, Woolloongabba, QLD 4102, Australia
Interests: wastewater-based epidemiology; analytical chemistry; environmental chemistry; (high-resolution) mass spectrometry; emerging contaminants; human exposure; risk assessment

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Guest Editor
Laboratory of Analytical Chemistry, Department of Chemistry, University of Athens, Panepistimiopolis Zografou, 157 71 Athens, Greece
Interests: emerging contaminants; (bio)transformation products; fate; ecotoxicology; analytical methods
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Special Issue Information

Dear Colleagues,

Wastewater-based epidemiology (WBE) has developed into an innovative approach able to provide epidemiological and socio-economic information about lifestyle habits, substance use, exposure to toxicants present in the environment and food, as well as public health and wellbeing. WBE is based on the chemical analysis of specific human urinary excretion products (biomarkers) in untreated wastewater as indicators of consumption, providing crucial data on the activity of the population served by the specific wastewater treatment plant. Initially, WBE was applied to evaluate spatial and temporal illicit drug use trends across Europe, and then it was further expanded worldwide. WBE was also used to obtain evidence on other biomarkers such as tobacco, caffeine, pesticides, plasticizers, pharmaceuticals, and endogenous compounds. This well-established approach offers the possibility to collect near-real-time, cost-effective, and continuous data in contrast to other methodologies such as conventional population surveys and human biomonitoring studies. It can provide crucial information about public health that can be of interest for policy-making and national and international organizations and committees. In the future, WBE could serve as an “early warning system” to help the authorities to prevent the spread of epidemics and make effective interventions on use of illicit substances.

Dr. Nikolaos I. Rousis
Prof. Dr. Nikolaos S. Thomaidis
Guest Editor

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Keywords

  • (illicit) drugs
  • new psychoactive substances
  • exposure biomarkers
  • population biomarkers
  • transformation products
  • sampling
  • stability experiments
  • monitoring
  • high-resolution mass spectrometry
  • site- and event-specific studies

Published Papers (1 paper)

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Research

18 pages, 2063 KiB  
Article
Assessment of Environmental Pollution and Human Exposure to Pesticides by Wastewater Analysis in a Seven-Year Study in Athens, Greece
by Nikolaos I. Rousis, Maria Denardou, Nikiforos Alygizakis, Aikaterini Galani, Anna A. Bletsou, Dimitrios E. Damalas, Niki C. Maragou, Kevin V. Thomas and Nikolaos S. Thomaidis
Toxics 2021, 9(10), 260; https://doi.org/10.3390/toxics9100260 - 11 Oct 2021
Cited by 14 | Viewed by 3534
Abstract
Pesticides have been used in large amounts around the world for decades and are responsible for environmental pollution and various adverse effects on human health. Analysis of untreated wastewater can deliver useful information on pesticides’ use in a particular area and allow the [...] Read more.
Pesticides have been used in large amounts around the world for decades and are responsible for environmental pollution and various adverse effects on human health. Analysis of untreated wastewater can deliver useful information on pesticides’ use in a particular area and allow the assessment of human exposure to certain substances. A wide-scope screening method, based on liquid chromatography coupled to quadrupole-time-of-flight mass spectrometry, was applied, using both target and suspect screening methodologies. Daily composite influent wastewater samples were collected for seven or eight consecutive days in Athens between 2014 and 2020 and analyzed for 756 pesticides, their environmental transformation products and their human metabolites. Forty pesticides were quantified at mean concentrations up to 4.9 µg/L (tralkoxydim). The most abundant class was fungicides followed by herbicides, insect repellents, insecticides and plant growth regulators. In addition, pesticide transformation products and/or metabolites were detected with high frequency, indicating that research should be focused on them. Human exposure was evaluated using the wastewater-based epidemiology (WBE) approach and 3-ethyl-carbamoyl benzoic acid and cis-1,2,3,6-tetrahydrophthalimide were proposed as potential WBE biomarkers. Wastewater analysis revealed the presence of unapproved pesticides and indicated that there is an urgent need to include more transformation products in target databases. Full article
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