Symmetry/Asymmetry in Molecular Medicinal Chemistry

A special issue of Symmetry (ISSN 2073-8994). This special issue belongs to the section "Chemistry: Symmetry/Asymmetry".

Deadline for manuscript submissions: closed (31 March 2024) | Viewed by 802

Special Issue Editors


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Guest Editor
Department of Pharmaceutical Chemistry, Faculty of Pharmacy, Iuliu Hațieganu University of Medicine and Pharmacy, 41 Victor Babeș Street, 400012 Cluj Napoca, Romania
Interests: medicinal chemistry; drug design; organic synthesis; heterocyclic compounds; biological activity; SAR; ADME; lipophilicity; PCA; K-means clustering; peptide chemistry
Special Issues, Collections and Topics in MDPI journals

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Guest Editor
Department of Pharmaceutical Chemistry, Iuliu Hațieganu University of Medicine and Pharmacy, 41 Victor Babeș Street, RO-400012 Cluj-Napoca, Romania
Interests: chemically synthetized and/or modified antimicrobial molecules; antimicrobial potential testing; antimicrobial resistance; molecular docking; molecular descriptors
Special Issues, Collections and Topics in MDPI journals
Department of Pharmaceutical Chemistry, "Iuliu Hațieganu" University of Medicine and Pharmacy, 41 Victor Babeș Street, RO-400012 Cluj-Napoca, Romania
Interests: chemical development (synthesis, structural analysis) of new heterocyclic molecules with antimicrobial; anticancer; anti-inflammatory; antioxidant potential

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Guest Editor
Department of Therapeutic Chemistry, "Iuliu Hațieganu" University of Medicine and Pharmacy, 8, Victor Babeș Street, 400012 Cluj-Napoca, Romania
Interests: synthetic organic chemistry; medicinal and pharmaceutical chemistry; anti-inflammatory synthesis of medicinal compounds; organic synthesis; heterocyclic chemistry; synthetic medicinal chemistry; heterocyclic compounds synthesis

Special Issue Information

Dear Colleagues,

The world contains a vast array of natural products, many of which have also become indispensable drugs for humans. However, many of these pharmaceutically active substances exist in two possible configurations (a phenomenon known as chirality) and are only effective in one of them, akin to mirror images of each other (enantiomers), and may even be harmful in the other form.

The concept of chirality is the pillar of asymmetric synthesis, which is one of most intriguing areas in medicinal chemistry.

Since the tragedy of racemic thalidomide usage, chiral separation and enantioselective synthesis have become prominent areas of research in chemistry. Most drugs on the market today have chiral compounds in them, and the number of enantiomerically pure drugs currently on the market is on the rise. At the same time, a full chirality analysis, including determination of absolute configuration and enantiomeric excess, becomes essential in pharmaceutical industry for quality control and in every step in the development of new drugs.

This Special Issue entitled “Symmetry/Asymmetry in Molecular Medicinal Chemistry” seeks original research papers and high-quality reviews in the fields of medicinal chemistry and symmetry/asymmetry of bioactive compounds.

Dr. Ioana Ionuț
Dr. Gabriel Marc
Dr. Anca Stana
Dr. Cătălin Araniciu
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Symmetry is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2400 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Published Papers

There is no accepted submissions to this special issue at this moment.
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